By Kimberly Chin

International stocks trading in New York closed lower on Wednesday. The S&P/BNY Mellon index of American depositary receipts fell 0.6% to 166.24. The European index tumbled 0.9% to 142.28. The Asian index fell 0.1% to 230.78. The Latin American index decreased 1.6% to 207.79. And the emerging-markets index notched down 0.1% to 402.25.

Renalytix AI PLC's ADRs rose 6% on Wednesday after the company said it was in an agreement with Atrium Health, Wake Forest Baptist Health and Wake Forest School of Medicine to improve kidney health and reduce kidney disease progression.

BP PLC's ADRs fell 2.5% on Wednesday after the company, along with Eni SpA, signed a non-binding memorandum of understanding to explore combining their upstream portfolios in Angola into a new joint venture.

JD.com Inc. rose 1.2% after the Chinese e-commerce company said its profit and revenue rose for the first quarter, with an increased contribution from service revenues.

Write to Kimberly Chin at kimberly.chin@wsj.com

(END) Dow Jones Newswires

May 19, 2021 20:04 ET (00:04 GMT)

Copyright (c) 2021 Dow Jones & Company, Inc.
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