ONCT Oncternal Therapeutics Inc

Item 2.02. Results of Operations and Financial Condition.

Oncternal Therapeutics, Inc. (“Oncternal”) estimates that its cash and cash equivalents were approximately $82.2 million as of March 31, 2022. This amount is preliminary and is subject to completion of financial closing procedures. As a result, this amount may differ from the amount that will be reflected in Oncternal’s financial statements as of and for the quarter ended March 31, 2022.

The information in this Item 2.02 shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such a filing.

Item 8.01. Results of Operations and Financial Condition.

On April 13, 2022, Oncternal announced that has deprioritized further development of its ONCT-216 product candidate, including discontinuing enrollment in Oncternal’s multicenter Phase 1/2 clinical trial of ONCT-216 as a single agent and in combination with vincristine in patients with relapsed or refractory Ewing sarcoma. Oncternal plans to reallocate resources primarily to its zilovertamab global registrational Phase 3 study ZILO-301.

Oncternal believes that its existing cash and cash equivalents as of March 31, 2022 will be sufficient to fund its projected operating requirements into the third quarter of 2023.

Forward-Looking Statements

Oncternal cautions readers that statements contained in this report regarding matters that are not historical facts are forward-looking statements. These statements are based on Oncternal’s current beliefs and expectations. Such forward-looking statements include Oncternal’s estimated cash and cash equivalents as of March 31, 2022, the allocation of its capital resources, and its forecast of the period of time through which Oncternal’s financial resources will be adequate to support its planned operations. Such forward-looking statements involve risks and uncertainties that could cause actual results to differ materially from predicted or expected results. Such risks and uncertainties include, but are not limited to, potential changes in estimated cash and cash equivalents based on the completion of financial closing procedures and release of complete first quarter 2022 results, risks associated with the clinical development and process for obtaining regulatory approval of Oncternal’s product candidates, such as potential delays in the commencement, enrollment and completion of clinical trials, the anticipated use of cash may increase as a result of factors outside of Oncternal’s control, including if the Food and Drug Administration or other regulatory authorities may require Oncternal to generate additional data or conduct additional preclinical studies or clinical trials, or impose other requirements beyond those that Oncternal currently anticipates, and other risks described in Oncternal’s filings with the Securities and Exchange Commission. Oncternal cautions readers not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and Oncternal undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.

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