By Sara Sjolin, MarketWatch

LONDON (MarketWatch) -- Most U.K. stocks headed south on Tuesday, with mining firms and GlaxoSmithKline PLC among the leading decliners, although the benchmark index trimmed losses after softer-than-expected inflation data.

The FTSE 100 index fell 0.2% to 6,714.74.

The index traded as low as 6,693.26 earlier in the day, but started paring losses after the Office for National Statistics said U.K. inflation came in at 2.2% in October, down from 2.7% in September and lower than the 2.5% forecast by analysts. A lower rate of inflation eases pressure on the central bank to tighten monetary policy.

"The easing in the rate of inflation and underlying price pressures will provide greater scope for monetary policy to be kept looser for longer and thereby helping ensure a sustainable upturn in the economy," said Chris Williamson, chief economist at Markit.

"Lower inflation reduces the risk of the Bank of England having to hike rates earlier than it may otherwise prefer to, allowing policy to focus on stimulating growth rather than warding off rising inflationary pressures," he added.

The pound (GBPUSD) tripped after the data and traded at $1.5867, down from late Monday's $1.5991.

Among notable movers in London, shares of GlaxoSmithKline PLC (GSK) gave up 1.4% after the drug maker said its heart-disease drug Darapladib missed its target in a phase-three trial.

Mining firms were also on the decline, tracking most metals prices lower. Shares of Anglo American PLC lost 1.4%, Glencore Xstrata PLC (GLCNF) fell 0.8%, BHP Billiton PLC (BHP) dropped 0.6% and Rio Tinto PLC (RIO) gave up 0.4%.

On a more upbeat note in London, Vodafone Group PLC (VOD) gained 0.7% after the wireless-telecoms giant said it swung to profit in the first half of the fiscal year. However, revenue for its existing services business declined in the second quarter.

CRH PLC climbed 3% after the building-materials firm reiterated its expectations for the second half of the year, as it reported a 2% rise in like-for-like sales in the third quarter.

Outside the main index in London, shares of TalkTalk Telecom Group PLC rallied 7.9% after the TV and telecoms firm raised its full-year revenue-growth guidance to at least 3% from 2%.

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