By Polya Lesova, MarketWatch

NEW YORK (MarketWatch) -- The U.K.'s benchmark stock index gained on Wednesday, led higher by the mining sector as investors awaited the U.S. Federal Reserve's statement on monetary policy.

The FTSE 100 index rose 0.5% to 6,461.30 in intraday trading. Most European markets were closed for the May Day holiday.

The Stoxx 600 index , a pan-European stock-market gauge, gained 0.1% to 297.02.

Mining shares led the FTSE 100 higher, even as China's official gauge of manufacturing activity fell to 50.6 in April, according to the National Bureau of Statistics. The manufacturing purchasing managers' index remained above the 50 mark that separates growth from contraction.

"The U.K. mining sector is in demand despite the Chinese manufacturing sector showing a marginal weakness in April," said Brenda Kelly, senior market strategist at IG, in emailed comments.

"With the index remaining above the pivotal 50 mark which separates expansion from contraction, the FTSE has shrugged off the unexpected slowdown," she said. "A strong quarter for Chilean mining group, Antofagasta, has helped underpin demand."

Shares of Antofagasta PLC rose 1.5% as the copper producer reported first-quarter copper output in line with expectations and reaffirmed its full-year targets.

Among other U.K.-listed miners, Randgold Resources Ltd. rallied 3.2% and Fresnillo PLC climbed 1.4%. Commodities trader Glencore International PLC rose 0.9%.

Banking shares also gained, with Standard Chartered PLC up 2% and Barclays PLC (BCS) up 1.5%.

The U.S. Federal Reserve's open market committee is due to make a monetary-policy announcement Wednesday. It's expected to keep its bond-buying program unchanged at $85 billion a month.

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