RNS No 5490c
DOMINO PRINTING SCIENCES PLC
25 October 1999

Schedule 10 - Notification of Major Interests in Shares

1   Name of company:
Domino Printing Sciences PLC

2   Name of shareholder having a major interest:
Barclays plc

3   Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18:
Barclays Bank plc

4   Name of registered holder(s) and, if more than one holder, the number of
shares held by each of them:
Chase Nominees Limited (16341)   58,251
Chase Nominees Limited (16344)    7,700
Chase Nominees Limited (16345)   12,900
Chase Nominees Limited (16376)    2,095
Chase Nominees Limited (16400)  175,918
Chase Nominees Limited (16480)  149,900
Chase Nominees Limited (16482)  301,309

5   Number of shares/amount of stock acquired:


6   Percentage of issued class:


7   Number of shares/amount of stock disposed:


8   Percentage of issued class:


9   Class of security:
Ordinary 5p shares

10  Date of transaction:
unknown

11  Date company informed:
Monday 25th October 1999

12  Total holding following this notification:
708,073

13  Total percentage holding of issued class following this notification:
3.016%

14  Contact name for queries:
Sue Bourne

15 Contact telephone number:
01954 781888

16  Name of company official responsible for making notification:
Richard Pryn  Company Secretary

17  Date of notification:
Monday 25th October 1999


END

HOLPBGGWUBGBGUA


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