TIDMNSCI

RNS Number : 4343U

NetScientific PLC

07 April 2016

7 April 2016

NetScientific plc

("NetScientific" or the "Group")

NetScientific Full Year Results year ended 31 December 2015

London, UK - 7 April 2016 - NetScientific plc (AIM: NSCI), the transatlantic healthcare technology group, announces its audited Full Year results for the year ended 31 December 2015.

Operational highlights:

-- Appointment of new CEO, François R. Martelet, M.D., who brings more than 20 years of biopharma experience and a proven track record of shaping and developing businesses to deliver shareholder returns

-- Lead portfolio companies, Vortex (95% ownership) and Wanda (71.3% ownership), advancing well with high calibre CEOs appointed to drive strategy and expedite commercialisation. Good progress made across other priority portfolio companies, ProAxsis (56.5% ownership) and Glycotest (87.5% ownership), where high calibre CEOs have also been appointed.

   --      Portfolio rationalisation completed with the divestment  of non-core assets 
   --      Portfolio now solely healthcare with the focus on accelerating growth in priority companies 

Financial highlights:

-- Capital raising of GBP18.2m (gross) successfully completed to principally fund the acceleration of Vortex and Wanda

-- Loss after tax of GBP12.7m (2014: loss GBP7.1m) reflecting close to commercialisation stage expenditure of lead and priority portfolio companies

   --      Available cash resources of GBP23.2m (at 31 December 2014: GBP16.8m) 

Post period end highlights:

   --      Wanda entered into two new commercial agreements with: 

o Health Resource Solutions, a leading US high-tech home nursing and therapy services group, for the use of its CHF/COPD product; and

o Dignity Health, the fifth largest health provider in the US, for its new Oncology platform

-- PDS Biotechnology signed a Cooperative Research and Development Agreement with the US National Cancer Institute to co-develop novel cancer immunotherapies through Phase II clinical trials

   --      Professor Stephen Smith joined the Board as Non-Executive Director 
   --      Appointment of Ian Postlethwaite as Chief Financial Officer 

Sir Richard Sykes, Chairman of NetScientific, said: "NetScientific's management team and portfolio focus has been completely transformed. Under François' leadership and with a focussed, close to commercialisation portfolio asset base, we now have an extremely strong healthcare technology group well positioned, not least through its majority shareholdings, to deliver significant value to shareholders."

- Ends -

For more information, please contact:

 
 NetScientific                            Tel: +44 (0)20 3514 1800 
  François R. Martelet, 
  M.D., CEO 
  Mark Nanovich, Interim 
  CFO 
 Investec (NOMAD and                      Tel: +44 (0)20 7597 4000 
  broker) 
  Gary Clarence / Daniel 
  Adams 
 
   Consilium Strategic                    Tel: +44 (0)20 3709 5700 
   Communications                netscientific@consilium-comms.com 
   Mary-Jane Elliott / 
   Chris Gardner / Jessica 
   Hodgson / Chris Welsh 
   / Laura Thornton 
 

About NetScientific

NetScientific is a transatlantic healthcare technology group with an investment strategy focused on sourcing, funding and commercialising technologies that significantly improve the health and well-being of people. For more information, please visit the website at www.netscientific.net.

Joint Statement from the Chairman & CEO

NetScientific is a transatlantic healthcare technology group with an investment strategy focused on sourcing, funding and commercialising technologies that significantly improve the health and well-being of people. In 2015 the Group underwent a successful transformation with the rationalisation of its portfolio and restructure of the management team, resulting in a streamlined group focused on holding majority positions and delivery and maximising shareholder value from its investments in digital health, diagnostics and therapeutics.

François R. Martelet, M.D. was appointed as CEO and Board Director in June 2015. He brings more than 20 years of biopharma experience and a proven track record of shaping and developing businesses to deliver returns. François has a broad experience in both large and small pharma and technology companies, deep knowledge of commercialisation, value creation and proven managerial capability. In April 2016, the Company announced that Ian Postlethwaite has accepted the role as Chief Financial Officer. Ian joins the Company from Allergy Therapeutics plc where he has held the position of Finance Director since 2002.

Over the year, the Group made significant progress with its portfolio companies, and specifically with its lead investments, Vortex, which is developing a novel liquid biopsy technology that could revolutionise cancer diagnosis, monitoring and treatment and Wanda, a digital health company with technology that uses machine learning to derive a personalized risk score for congestive heart failure patients. Beyond Vortex and Wanda, other priority portfolio companies have attracted high calibre, experienced CEOs to drive the next phase of growth to commercialisation. In November 2015 the Group successfully completed an GBP18.2m (gross) capital raising supported by new and existing shareholders to accelerate the development of its lead portfolio companies.

Finance

For the year, the Group made a loss of GBP12.7 million (2014: loss GBP7.1 million) which is split between continuing and discontinued operations as follows:

   -       Continuing operations                       GBP11.2 million (2014: GBP6.2 million) 
   -       Discontinued operations                   GBP1.5 million (2014: GBP0.9 million) 

The loss principally reflects the business model where the portfolio companies are largely subsidiaries developing their technologies and are therefore currently loss making.

The loss from continuing operations includes GBP7.3 million (2014: GBP3.1 million) of research and development costs primarily incurred in Vortex and Wanda and reflects the increased level of investment to drive the underlying technologies/products of these key portfolio companies towards commercialisation.

General and administrative costs included within continuing operations of GBP3.2 million (2014: GBP2.5 million) includes central costs incurred in managing the portfolio companies, corporate costs and sales and marketing/administrative costs incurred by the portfolio companies. The increase during the period represented the uplift in sales and marketing costs and administrative costs of the portfolio companies. Other costs of GBP1.1 million (2014: GBP0.7 million) incorporated in continuing operations included GBP0.5 million (2014: GBPnil) for redundancy costs associated with the restructure of the management team and review of operations. Headcount across the Group at end of year, excluding non-executive directors, was 47 (2014: 28).

The loss from discontinued operations comprises the operating loss incurred by the discontinued subsidiaries during the year of GBP0.8 million (2014: GBP0.9 million), share of loss from associates and joint ventures of GBP0.4 million (2014: GBP0.1 million) and the net loss of GBP0.3 million (2014: GBPnil) recorded on the disposal of these entities. The principal entities disposed of during the year were Frontier Biosciences Limited, MOF Technologies Limited, Morphodyne SA, Qlida Diagnostics Limited and RoboScientific Limited. Group non-current liabilities which existed at 31 December 2014 of GBP0.7 million and represented loans and borrowing and other creditors of discontinued operations have been transferred with these entities on their disposal.

Cash on the balance sheet as at 31 December 2015 was GBP23.2 million (31 December 2014: GBP16.9 million). Cash used in operations, excluding net proceeds of GBP17.1m from capital raising, was GBP11.0 million (2014: GBP8.8 million). The cash balance as at 31 March 2016 was GBP19.5 million

Strategy

The business strategy is based on funding and building game changing healthcare technology companies towards value inflection points and eventual exit including through a trade sale or public listing. The Group sources opportunities from global institutions, leading technology incubators and its deep healthcare network. In the early stages of the company's development the Group provides extensive management support including technical guidance, administrative support, legal, IP and commercial expertise. As companies mature through key milestones the Group will recruit experienced industry leading CEOs to drive the next phase of growth, attract additional external capital and secure favourable exits.

Portfolio Review

As at 31 December 2015, the Group had five core portfolio companies, including two lead assets, in which it has a controlling interest: Vortex Biosciences, Inc., Wanda, Inc., ProAxsis Ltd, Glycotest, Inc. and Glucosense Diagnostics Limited. It also has a material investment in PDS Biotechnology Corporation., and five seed stage Investments: EpiBone Inc., G-Tech Inc., Longevity Biotech Inc., Neumitra Inc., and CytoVale Inc.

The Group will continue to focus on the five core portfolio companies and actively manage the remaining portfolio, seeking to maximise shareholder return in the form of capital growth. However, there are no fixed targets for the length of time during which an investment may be held, as this will be dependent both on progress and availability of funding, with a view to maximising shareholder value and generating funds for re-investment in the pipeline.

Portfolio companies

Vortex Biosciences

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Vortex Biosciences is a US based cancer diagnostic company, developing a novel liquid biopsy automated instrument (VTX-1) and microfluidic cartridge for the isolation of circulating tumour cells from whole blood without the need for any pre-treatment. The label-free technology enables high purity and collection efficiency of intact circulating tumour cells in less than an hour. The technology enables researchers and clinicians to non-invasively capture, identify, analyse and enumerate tumour cells for use in downstream clinical applications, such as cancer diagnosis and monitoring, personalised medicine, drug development, and cancer research in the estimated US$22 billion liquid biopsy market (JP Morgan Liquid Biopsy Report - 27 May, 2015).

Gene Walther was appointed as CEO on 4 January 2016. Gene brings over 20 years' impressive experience as a leading diagnostics executive. Gene was the Deputy Director, Diagnostics, for the Bill & Melinda Gates Foundation, Executive Chairman of the Board of GenturaDx where he led this start-up diagnostics firm through product development leading to its acquisition by Luminex. He spent 11 years at Novartis as President and Global Head of Diagnostics and several roles at Chiron including President and Vice President across the diagnostics and global commercial development teams. In addition, several key hires were made during the first quarter of 2016 including a Chief Commercial Officer, Vice President of Manufacturing and Director of Quality.

During 2015, Vortex made significant progress on both the development of VTX-1 instrument and the integrated microfluidic cartridge. In addition, Vortex was granted a critical US patent which covers its core technology of inertial microfluidics and its application to the separation and collection of cells of interest including circulating tumour cells. The patent also covers collection of circulating tumour cells from the chip for downstream analysis such as counting, cytology and DNA sequencing. Alongside three previously issued patents, this grant strengthens Vortex's global market position as the company prepares to commercialise VTX-1. ISO certified contract manufacturing partners for both the instrument and the microfluidic cartridge have been selected and will be transitioning to scale manufacturing to support placements.

The new management team has reviewed previous commercialisation plans and now intends to ship the VTX-1 instrument to selected leading US researchers for Beta testing in the second quarter of 2016. Additionally, the VTX-1 will be introduced to the broader cancer research market at the American Association for Cancer Research in New Orleans on 17-20 April, 2016. Vortex continues to drive towards its key milestone of commercial launch into the clinical research market in 2017.

NetScientific shareholding in Vortex is 95% and as at 31 December 2015, it has invested GBP5.6 million. Grant funding received to develop Vortex's underlying technology was GBP1.6 million.

Wanda

Wanda is a San Francisco based digital health company commercialising advanced clinical decision support software. Wanda aims to significantly reduce hospitalisation risk, and improve the quality of life, for people with chronic conditions, initially focused on congestive heart failure (CHF). In the US chronic disease accounts for 80% of the total health care bill and represents a US$1.4 trillion expenditure, a significant proportion of which is avoidable through better management and appropriate clinical interventions.

Steve Curd joined as CEO in September 2015. He has more than 20 years' experience in driving growth for digital health companies, commercialising products and delivering exits. Steve has helped secure 15 M&A transactions and numerous successful exits for digital health companies. Most recently, Steve was the COO of NantHealth, a healthcare company converging biomolecular medicine and bioinformatics with technology services, where he was responsible for advancing its product portfolio, driving improvements in efficiency and improving client satisfaction. Other notable positions include CEO at CareInSync, CIO at UnitedHealth Group, COO at WebMD and CEO at VantageMed. The existing team was strengthened during the year as headcount grew from 8 to 17, including the appointment of a Chief Collaboration Officer to drive commercialisation.

During 2015, Wanda completed development of its Congestive Heart Failure (CHF) algorithms, and added analytics for Chronic Obstructive Pulmonary Disease (COPD), as well as a combined CHF/COPD predictive capability. As oncology diagnostic and therapeutic techniques have continued to advance, Wanda added the capability to coordinate decision support for oncology care teams in an effort to help relegate most cancers to the category of chronic conditions. Subsequent to a complete business review by the new management team it was decided to restructure the Triventis collaboration with iMPak Health and it is likely that Triventis will be dissolved with there being no financial obligation to NetScientific with regards to dissolution. The Triventis collaboration has provided valuable insight and learning about the market's expectations for the provision of a digital health solution for managing chronic diseases. This has enabled the team to clearly define the optimum solution for target end-users.

In early 2016 Wanda signed a contract with a leading US hi-tech home nursing and therapy services group, Health Resource Solutions ('HRS'), for the use of its CHF/COPD product. In addition, Wanda signed a collaborative agreement with the fifth largest health provider organization in the United States (Dignity Health) to launch its new oncology platform (Oncoverse). With a new experienced CEO in place, a world-class Silicon Valley team formed and commercial products on the market, Wanda now plans to seek external funding in 2016 to capitalise on the significant opportunities in the digital healthcare space.

NetScientific shareholding in Wanda is 71.3% and as at 31 December 2015, it has invested GBP5.1 million. Grant funding received to develop Wanda's underlying technology was GBP7.7 million.

ProAxsis

ProAxsis is a medical diagnostics company, based in Northern Ireland, developing a range of products for the capture, detection and measurement of active protease biomarkers of diseases. The rapid and easy-to-use tests ProAxsis has developed incorporate patented ProteaseTags(R); smart molecules which trap an active protease within a complex biological sample and enable a visual readout of its presence. The initial applications for the technology are focused on managing the chronic respiratory diseases, Cystic Fibrosis (CF) and Chronic Obstructive Pulmonary Disease (COPD), where exacerbations have a major impact on the long-term prognosis of patients. There are 70,000 patients diagnosed with CF worldwide and 35.7m patients with COPD in the US and EU alone.

Dr. David Ribeiro was recruited as CEO in October 2015. He has extensive experience in commercialising products within chronic diseases, having previously held senior management roles at Solvay Healthcare, Encysive Pharmaceuticals, Pfizer and Pharmaxis Pharmaceuticals Limited.

ProAxsis made excellent progress in 2015 with the commercial launch of its immunoassay kit for research labs, as well as securing its first customers, including a major pharma company. Separately, the company made significant progress with the development of its point-of-care test for neutrophil elastase, which is expected to be ready for commercialisation in early 2017. ProAxsis will seek to raise additional funds in 2016 to principally develop its point-of-care test (NEATstik) and fund a clinical trial for COPD.

NetScientific shareholding in ProAxsis is 56.5% and as at 31 December 2015, it has invested GBP0.1 million. Grant funding received to develop ProAxsis's underlying technology was GBP1.0 million.

Glycotest

Glycotest is a US based liver diagnostics company seeking to commercialise new and unique blood tests for life threatening liver cancers and fibrosis-cirrhosis with exclusive world-wide rights to over 50 patent-protected serum protein biomarkers. Glycotest's lead product is its HCC panel, a biomarker panel driven by a proprietary algorithm for curable early-stage hepatocellular carcinoma (HCC), the most common form of primary liver cancer. The market for HCC testing is large and growing with currently three million patients and in excess of US$800m in the US alone.

In late 2015, Larry Cohen was appointed CEO. Larry is a diagnostic industry leader who has held executive positions at large diagnostic companies such as Ortho-Clinical Diagnostics (J&J), International Technidyne Corporation (ITC), the diagnostic division of Thoratec and Beckman Instruments. He has also been CEO of venture backed start-ups such as HemoSense (acquired by Alere), SenGenix and Exalenz Bioscience (TASE).

In 2015, a 208 patient head-to-head clinical study was performed which demonstrated the excellent performance of the Glycotest HCC panel's ability to detect curable, early-stage liver cancer (HCC) versus currently used blood tests.

In the first quarter of 2016, Glycotest created a Medical Advisory Board consisting of experts in hepatology and molecular diagnostics. The aim for 2016 is to accelerate commercialisation by seeking additional external financing to develop commercial grade kits for use in a CLIA laboratory to be opened in late 2016 or early 2017.

NetScientific shareholding in Glycotest is 87.5% and as at 31 December 2015, it has invested GBP1.2 million. Grant funding received to develop Glycotest's underlying technology was GBP5.9 million.

Glucosense

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Glucosense is developing a non-invasive glucose sensor, which has a number of potential applications as a replacement for current invasive tests that are inconvenient and uncomfortable for the patient. These include a partial replacement for finger-prick testing, continuous non-invasive glucose monitoring and as a wearable hypoglycaemia-alert device. According to the International Diabetes Federation, in 2015 there were an estimated 415 million adults worldwide with diabetes, including 193 million who are undiagnosed, and a further 318 million adults are estimated to have impaired glucose tolerance.

In 2015 the company continued the development of a second generation prototype to support the next phase of clinical testing. A full time Programme Director was appointed in July 2015 to oversee this work and a number of technical expert advisors have subsequently been engaged.

NetScientific shareholding in Glucosense is 60.7% and as at 31 December 2015, it has invested GBP0.7 million.

PDS

PDS is a clinical stage immunotherapy company developing a next-generation of simpler, safer and more effective immunotherapies for cancer and infectious diseases. Versamune(R), its novel synthetic nanoparticle platform technology, activates multiple immunological mechanisms which direct the targeting of cancer and infectious disease by the immune system.

In May 2015 PDS announced positive preliminary data showing that its lead cancer immunotherapy treatment, PDS0101, has generated strong T-cell responses in pre-cervical cancer. In February 2016 PDS signed a Cooperative Research and Development Agreement with the National Cancer Institute, a division of the US National Institutes of Health. The goal is to co-develop novel cancer immunotherapies through Phase II clinical trials that will start in 2016 and 2017. PDS has recently strengthened its senior management team with the recruitment of a Chief Medical Officer and VP of Drug Development and Manufacturing.

NetScientific has invested GBP1.76m for a 14.85% shareholding in PDS.

Board changes

Post year end, the Group was pleased to announce the appointment of Professor Stephen Smith as Non-Executive Director. Stephen has held senior leadership roles in the NHS and academia. He has had a long and distinguished career as a clinician scientist, Head of Department, Dean and CEO with the Medical Research Council, University of Cambridge, Imperial College, London and Imperial College Healthcare NHS Trust. During his career, Stephen has also spun two companies out of Cambridge - Metris Therapeutics Ltd and GNI Group Ltd. GNI was established as a start up in Japan in 2001 and successfully achieved an Initial Public Offering (IPO) on the Tokyo Stock Exchange six years later.

In addition, Ian Postlethwaite has accepted the role of Chief Financial Officer of the Group. Ian has been the Finance Director of Allergy Therapeutics plc for 14 years and has been a significant contributor to the success of the company. During this time Allergy Therapeutics became listed on AIM, achieved a number of financial goals, including two fund raisings in 2015 to support the company's clinical and other development plans, and has growing revenues from products on sale in Europe.

We wish to thank past Directors for their valuable contributions to Netscientific.

Outlook

In 2015 the Group underwent a significant transformation with key management changes, including the appointment of a new blue-chip Group CEO and CFO and streamlining of assets resulting in a tightly run, highly focused healthcare portfolio. Following the successful capital raising in November 2015 we are able to accelerate key portfolio companies towards major milestones and commercialisation. The prime focus in 2016 across the Group is on execution and delivery.

We remain very encouraged by the quality of our priority portfolio companies where we have been able to recruit outstanding CEOs in their respective fields to complete the process of bringing the cutting-edge technologies to commercialisation. We believe these leaders have the track record and experience needed to drive the next phase of commercial growth and attract additional third party validation capital, which will lead to significant shareholder value creation. We will continue to focus heavily in these companies throughout 2016.

 
 Sir Richard Sykes        François R. 
                           Martelet, M.D 
 Non-Executive Director   Chief Executive Officer 
  and Chairman 
 6 April 2016             6 April 2016 
 

CONSOLIDATED INCOME STATEMENT

FOR THE YEAR ENDED 31 DECEMBER 2015

 
                                            Notes        2015            2014 
                                                          GBP             GBP 
 Continuing Operations 
-----------------------------------------  ------  ---------------  -------------- 
 
   Revenue                                                  78,577               - 
 Cost of sales                                             (6,447)               - 
-----------------------------------------  ------  ---------------  -------------- 
                                                                                 - 
   Gross profit                                             72,130 
 
 Other operating income                                     43,864          24,338 
 Research and development costs                        (7,256,285)     (3,098,067) 
 General and administrative costs                      (3,182,454)     (2,495,450) 
 Other costs                                           (1,077,110)       (717,001) 
 
   Loss from operations                               (11,399,855)     (6,286,180) 
 
   Finance income                                           77,692          77,435 
 Finance expense                                             (137)               - 
 
   Loss before taxation                               (11,322,300)     (6,208,745) 
 
   Income tax credit                                        93,550          29,821 
-----------------------------------------  ------  ---------------  -------------- 
 
   Loss for the year from continuing 
   operations                                         (11,288,750)     (6,178,924) 
 
 
 Discontinued Operations 
-----------------------------------------  ------  ---------------  -------------- 
 
 Loss for the year from discontinued 
  operations                                  5        (1,517,696)       (947,874) 
-----------------------------------------  ------  ---------------  -------------- 
 
 Loss for the year                                    (12,746,446)     (7,126,798) 
-----------------------------------------  ------  ---------------  -------------- 
 
 
 Loss attributable to: 
 Owners of the parent                         4       (10,841,924)     (6,425,011) 
 Non-controlling interests                             (1,904,522)       (701,787) 
-----------------------------------------  ------  ---------------  -------------- 
 
                                                      (12,746,446)     (7,126,798) 
-----------------------------------------  ------  ---------------  -------------- 
 
 Basic and diluted loss per share from 
  continuing and discontinued operations 
  attributable to owners of the parent 
  during the year: 
 Continuing operations                                     (25.4p)         (15.7p) 
 Discontinued operations                                    (3.0p)          (2.2p) 
 
 From loss for the year                                    (28.4p)         (17.9p) 
-----------------------------------------  ------  ---------------  -------------- 
 

CONSOLIDATED INCOME STATEMENT AND OTHER COMPREHENSIVE INCOME

FOR THE YEAR ENDED 31 DECEMBER 2015

 
                                                      2015            2014 
                                                       GBP             GBP 
 
   Loss for the year                               (12,746,446)     (7,126,798) 
 Items that may be subsequently reclassified 
  to profit or loss: 
 Exchange differences on translation 
  of foreign operations                                 245,443         295,989 
                                                ---------------  -------------- 
 
   Total comprehensive loss for the year           (12,501,003)     (6,830,809) 
                                                ---------------  -------------- 
 
 
 Attributable to: 
 Owners of the parent            (10,596,481)     (6,129,022) 
 Non-controlling interests        (1,904,522)       (701,787) 
                              ---------------  -------------- 
 
                                 (12,501,003)     (6,830,809) 
                              ---------------  -------------- 
 

All other comprehensive income will be reclassified to retained earnings on the ultimate sale of any relevant subsidiary company.

CONSOLIDATED STATEMENT OF FINANCIAL POSITION

AS AT 31 DECEMBER 2015

 
                                                           2015            2014 
                                               Notes        GBP             GBP 
 ASSETS 
 NON-CURRENT ASSETS 
 Intangible assets                                               513          10,244 
 Property, plant and equipment                               285,015         348,245 
 Investments in equity accounted associates                        -         228,883 
 Investments in equity accounted joint 
  ventures                                                         -               - 
 Available for sale investments                  7         1,806,608       1,806,608 
 Derivative financial assets                     8           100,159         100,159 
 Other receivables                                           753,583         545,606 
                                                      --------------  -------------- 
                                                           2,945,878       3,039,745 
                                                      --------------  -------------- 
 
 CURRENT ASSETS 

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 Trade and other receivables                                 559,775         853,022 
 Cash and cash equivalents                                23,239,047      16,867,198 
                                                      --------------  -------------- 
                                                          23,798,822      17,720,220 
                                                      --------------  -------------- 
 TOTAL ASSETS                                             26,744,700      20,759,965 
                                                      --------------  -------------- 
 
   LIABILITIES 
   CURRENT LIABILITIES 
 Trade and other payables                                (2,156,180)     (1,281,242) 
 Loans and borrowings                                       (50,137)        (43,250) 
                                                      --------------  -------------- 
                                                         (2,206,317)     (1,324,492) 
                                                      --------------  -------------- 
 NON CURRENT LIABILITIES 
 Trade and other payables                                          -        (52,537) 
 Loans and borrowings                                              -       (687,369) 
                                                                   -       (739,906) 
                                                      --------------  -------------- 
 TOTAL LIABILITIES                                       (2,206,317)     (2,064,398) 
                                                      --------------  -------------- 
 
   NET ASSETS                                             24,538,383      18,695,567 
                                                      --------------  -------------- 
 
 ISSUED CAPITAL AND RESERVES 
  ATTRIBUTABLE TO THE PARENT 
 Called up share capital                                   2,553,785       1,795,101 
 Share premium account                                    47,232,755      30,844,552 
 Capital reserve account                                     236,745         236,745 
 Foreign exchange reserve                                    691,563         446,120 
 Retained earnings                                      (24,371,018)    (13,529,442) 
                                                      --------------  -------------- 
 
   Equity attributable to the owners 
   of the parent                                          26,343,830      19,793,076 
 
   Non-controlling interests                             (1,805,447)     (1,097,509) 
                                                      --------------  -------------- 
 
   TOTAL EQUITY                                           24,538,383      18,695,567 
                                                      --------------  -------------- 
 

CONSOLIDATED STATEMENT OF CHANGES IN EQUITY

FOR THE YEAR ENDED 31 DECEMBER 2015

 
                                                                           Shareholders' equity 
                 ------------------------------------------------------------------------------ 
 
                                                                        Foreign                          Non- 
                      Share         Share   Capital        Retained    exchange                   controlling           Total 
                    capital       premium   reserve        earnings     reserve           Total     interests          equity 
                        GBP           GBP       GBP             GBP         GBP             GBP           GBP             GBP 
---------------  ----------  ------------  --------  --------------  ----------  --------------  ------------  -------------- 
 1 January 
  2014            1,795,101    30,844,552   236,745     (7,459,726)     150,131      25,566,803     (667,271)      24,899,532 
 
 Comprehensive 
  Income 
 Loss for 
  the year                -             -         -     (6,425,011)           -     (6,425,011)     (701,787)     (7,126,798) 
 Other 
  comprehensive 
  income                  -             -         -               -     295,989         295,989             -         295,989 
 Acquisition 
  of subsidiary           -             -         -               -           -               -        78,580          78,580 
 Increase 
  in subsidiary 
  shareholding            -             -         -       (489,893)           -       (489,893)       489,893               - 
 Dilution 
  in subsidiary 
  shareholdings           -             -         -         128,187           -         128,187     (128,187)               - 
 Disposal 
  of 
  subsidiaries            -             -         -               -           -               -         2,785           2,785 
 Foreign 
  exchange 
  differences             -             -         -               -           -               -     (171,552)       (171,552) 
 Share-based 
  payments                -             -         -         717,001           -         717,001             -         717,001 
---------------  ----------  ------------  --------  --------------  ----------  --------------  ------------  -------------- 
 Total 
  comprehensive 
  income                  -             -         -     (6,069,716)     295,989     (5,773,727)     (430,238)     (6,203,965) 
---------------  ----------  ------------  --------  --------------  ----------  --------------  ------------  -------------- 
 
 31 December 
  2014            1,795,101    30,844,552   236,745    (13,529,442)     446,120      19,793,076   (1,097,509)      18,695,567 
 
 Comprehensive 
  Income 
 Loss for 
  the year                -             -         -    (10,841,924)           -    (10,841,924)   (1,904,522)    (12,746,446) 
 Other 
  comprehensive 
  income                  -             -         -               -     245,443         245,443             -         245,443 
 Increase 
  in subsidiary 
  shareholding            -             -         -       (170,520)           -       (170,520)       220,240          49,720 
 Disposal 
  of 
  subsidiaries            -             -         -               -           -               -     1,087,447       1,087,447 
 Foreign 
  exchange 
  differences             -             -         -               -           -               -     (111,103)       (111,103) 
 Issue of 
  share capital     758,684    17,449,727         -               -           -      18,208,411             -      18,208,411 
 Costs of 
  share issue             -   (1,061,524)         -               -           -     (1,061,524)             -     (1,061,524) 
 Share-based 
  payments                -             -         -         170,868           -         170,868             -         170,868 
 Total 
  comprehensive 
  income            758,684    16,388,203         -    (10,841,576)     245,443       6,550,754     (707,938)       5,842,816 
---------------  ----------  ------------  --------  --------------  ----------  --------------  ------------  -------------- 
 
 31 December 
  2015            2,553,785    47,232,755   236,745    (24,371,018)     691,563      26,343,830   (1,805,447)      24,538,383 
 
 
 

CONSOLIDATED STATEMENT OF CASH FLOWS

FOR THE YEAR ENDED 31 DECEMBER 2015

 
                                                          2015              2014 
                                                           GBP               GBP 
 Cash flows from operating activities 
 Loss before income tax including discontinued 
 operations                                            (12,854,407)      (7,313,806) 
 Adjustments for: 
 Depreciation of property, plant and 
  equipment                                                 129,831           65,981 
 Amortisation of intangible assets                           55,336            1,614 
 Loss on disposal of property, plant 
  and equipment                                               3,432              768 
 Share of loss of associates and joint 
  venture                                                   399,656          119,991 
 Gain on sale of associates and joint                     (214,331)                - 
  venture 
 Loss on disposal of subsidiaries                           508,046                - 
 Impairment of intangible assets                            190,631          641,767 
 Provision against recoverability of                        176,677                - 
  loan 
 Share-based payments                                       170,868          717,001 
 Bad debt written off                                         3,557                - 
 Foreign exchange gains                                    (84,145)                - 
 Finance income                                            (77,695)         (77,465) 
 Finance costs                                               51,397           45,671 
                                                    --------------- 
                                                       (11,541,147)      (5,798,478) 
 
 Changes in working capital: 
 Increase in trade and other receivables                   (54,880)        (962,051) 
 Increase in trade and other payables                       881,717          129,757 
                                                   ----------------   -------------- 
 
   Cash used in operations                             (10,714,310)      (6,630,772) 
                                                   ----------------   -------------- 
 
 Income tax received                                         83,199           19.399 
                                                   ----------------   -------------- 
 
   Net cash used in operating activities               (10,631,191)      (6,611,373) 
                                                   ----------------   -------------- 
 
 Cash flows from investing activities 
 Investment in joint venture                               (34,981)         (35,119) 
 Investment in associate                                   (24,999)        (239,189) 

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 Proceeds from sale of associate                             24,999                - 
 Purchase of derivative financial assets                  (426,000)        (100,159) 
 Proceeds from sale of derivative financial                 426,000                - 
  assets 
 Disposal of discontinued subsidiaries,                   (109,431)                - 
  net of cash disposed of 
 Purchase of property, plant and equipment                (136,460)        (337,469) 
 Proceeds from sale of property, plant 
  and equipment                                                 650            1,054 
 Purchase of intangible assets                            (163,672)                - 
 Interest received                                           37,786           66,661 
 Proceeds on change in subsidiary shareholding                  720                - 
 Cash acquired on acquisition of subsidiary                       -           52,000 
 Purchase of available for sale investments                       -      (1,806,606) 
 
   Net cash used in investing activities                  (405,388)      (2,398,827) 
                                                   ----------------   -------------- 
 
   Cash flows from financing activities 
 Proceeds from borrowings                                    50,000          190,000 
 Proceeds from share issue                               18,208,411                - 
 Share issue cost                                       (1,061,524)                - 
 
   Net cash from financing activities                    17,196,887          190,000 
                                                   ----------------   -------------- 
 
 Increase / (decrease) in cash and 
  cash equivalents                                        6,160,308      (8,820,200) 
 Cash and cash equivalents at beginning 
  of year                                                16,867,198       25,546,951 
 Exchange gains on cash and cash equivalents                211,541          140,447 
                                                   ----------------   -------------- 
 
   Cash and cash equivalents at end of 
   year                                                  23,239,047       16,867,198 
                                                   ----------------   -------------- 
 
 

NOTES TO THE FINANCIAL INFORMATION FOR THE YEAR ENDED 31 DECEMBER 2015

   1.             General Information 

The Company is a public limited company incorporated on 12 April 2012 and domiciled in England with registered number 08026888 and its shares are listed on the Alternative Investment Market (AIM) of the London Stock Exchange.

   2              Basis of preparation 

The preliminary results of the year ended 31 December 2015 have been extracted from audited accounts which have not yet been delivered to the Registrar of Companies.

The Financial Statements set out in this announcement do not constitute statutory accounts for the year ended 31 December 2015.

The report of the auditors on the statutory accounts for the year ended 31 December 2015 was unqualified and did not contain a statement under Section 498 of the Companies Act 2006. The Financial Statements for the year ended 31 December 2015 included in this announcement were authorised for issue in accordance with a resolution of the Board of Directors on 6 April 2016.

   3.             Significant accounting policies 

The Group financial information has been prepared in accordance with International Financial Reporting Standards as adopted by the European Union that are effective for accounting periods beginning on or after 1 January 2015.

While the financial information included in this preliminary announcement has been prepared in accordance with IFRS, this announcement does not in itself contain sufficient information to comply with IFRS.

   4.             LOSS PER SHARE 

The basic and diluted loss per share is calculated by dividing the loss for the financial year by the weighted average number of ordinary shares in issue during the year. Potential ordinary shares from outstanding options at 31 December 2015 of 3,081,936 are not treated as dilutive as the entity is loss making

 
                                             2015          2014 
                                              GBP           GBP 
-------------------------------------   -------------  ------------ 
 Loss attributable to equity holders 
  of the Company 
 
 Continuing operations                      9,697,459     5,636,685 
 Discontinued operations                    1,144,465       788,326 
                                        -------------  ------------ 
 Total                                   (10,841,924)   (6,425,011) 
                                        -------------  ------------ 
 
 Number of shares 
 Weighted average number of ordinary 
  shares in issue                          38,228,552    35,902,020 
 
 
   5.         DISCONTINUED OPERATIONS 

Following a review of the Group's strategy and portfolio to focus on core projects, certain subsidiaries, associates and joint ventures were disposed of during the year.

The results of the discontinued operations, which have been included in the consolidated income statement, were as follows.

 
                                               Year ended    Year ended 
                                                   2015          2014 
                                                   GBP           GBP 
-------------------------------------------   ------------  ------------ 
 
   Revenue                                          50,928        51,921 
 Cost of sales                                    (24,244)      (17,732) 
                                              ------------  ------------ 
 Gross profit                                       26,684        34,189 
 
 Other operating income                            404,001       266,867 
 
 Research and development costs                (1,149,716)     (542,949) 
 General and administrative costs                 (68,448)      (55,769) 
 Impairment of intangible assets                         -     (641,767) 
 
 Loss from operations                            (787,479)     (939,429) 
 
 Finance income                                          3            29 
 Finance expenses                                 (51,260)      (45,671) 
 Share of loss of associates and joint 
  venture                                        (399,656)     (119,991) 
 
 Loss before taxation                          (1,248,392)   (1,105,062) 
 
 Attributable tax credit                          (14,411)     (157,188) 
                                              ------------  ------------ 
 
 Loss after tax                                (1,223,981)     (947,874) 
                                              ------------  ------------ 
 
 Gain on sale of associates and joint              214,331             - 
  venture 
 Loss on divestment of subsidiaries              (508,046)             - 
 Attributable tax expense                                -             - 
                                              ------------  ------------ 
 
 Loss from sale of discontinued operations       (293,715)             - 
  after tax 
                                              ------------  ------------ 
 
 Loss for the year                             (1,517,696)     (947,874) 
                                              ------------  ------------ 
 
 

Subsidiaries disposed of during the year:

 
                                                                          Proportion 
                                                    Proportion           of ownership 
                                                         of                interest 
                                   Country           ownership      held by non-controlling 
                                      of              interest             interests 
                                incorporation      at 31 December       at 31 December 
  Name                         or registration         2014*                 2014* 
---------------------------  ------------------   ---------------  ------------------------ 
 
  MOF Technologies Limited           UK                 51%                  49% 
  RoboScientific Limited             UK                 80%                  20% 
  Nearfield Communications 
   Limited                           UK                100%                   - 
  Watermass Limited                  UK                100%                   - 
 
  Advanced BioSensors, 
   Inc.                              USA                37%                  63%% 
  Advanced Cardiotech, 
   Inc.                              USA               87.5%                12.5% 
  Cardio-Scientific, 
   Inc.                              USA               100%                   - 
  Moftek, Inc.                       USA               100%                   - 
  Qlida Diagnostics, 
   Inc.                              USA               51.2%                48.8% 
 
  Morphodyne SA                     Swiss               60%                  40% 
 
   *           Interests were unchanged at time of disposal. 

Associates disposed of during the year:

 
 
  Name 
-------------------- 
 
DName-iT NV 
Frontier BioSciences 
 Limited 
 

Joint venture disposed of during the year:

 
 
    Name 
----------------------- 
 
  Butterfly BioSciences 
   LLC 
 
   6.             INVESTMENTS IN SUBSIDIARY UNDERTAKINGS 

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The Group had the following principal subsidiaries at 31 December 2015:

 
                                                                            Proportion        Proportion 
                                                                           of ownership      of ownership 
                                                 Proportion  Proportion      interest          interest 
                                                     of          of           held by           held by 
                                                  ownership   ownership   non-controlling   non-controlling 
                                   Country        interest    interest       interests         Interests 
                                      of            at 31       at 31          at 31             at 31 
                                incorporation     December    December       December          December 
  Name                         or registration      2015        2014           2015              2014 
---------------------------  ------------------  ----------  ----------  ----------------  ---------------- 
 
  NetScientific UK Limited           UK             100%        100%            -                 - 
  ProAxsis Ltd                       UK            56.5%       56.5%          43.5%             43.5% 
  Glucosense Diagnostics 
   Limited                           UK            60.7%        100%          39.3%               - 
 
  NetScientific America, 
   Inc.                             USA             100%        100%            -                 - 
  Vortex BioSciences, 
   Inc. (i)                         USA             95%         95%             5%                5% 
  Wanda, Inc. (i)                   USA            71.3%       71.3%          28.7%             28.7% 
  Glycotest, Inc. (i)               USA            87.5%       87.5%          12.5%             12.5% 
  Triventis Health LLC 
   (ii)                             USA             55%          -             45%                - 
 
 
 

For all undertakings listed above, the country of operation is the same as its country of incorporation or registration.

(i) Options have been issued by Vortex BioSciences, Inc., Wanda, Inc. and Glycotest, Inc. which if exercised would dilute the Company's shareholding by 19%, 14% and 14% respectively.

(ii) On 27 April 2015, the Group subscribed for a 55% interest in Triventis Health LLC, a digital health sales and marketing company. The price paid for the interest was US$0.55. Triventis Health LLC was formed on 20th April 2015 and was dormant and did not trade until 27 April 2015.

   7.         AVAILABLE FOR SALE INVESTMENTS 
 
 Represent unquoted equity securities 
                                             2015          2014 
                                              GBP           GBP 
--------------------------------------   ------------  ------------ 
 
 At 1 January                               1,806,608             2 
 Additions                                          -     1,806,606 
---------------------------------------  ------------  ------------ 
 
   At 31 December                           1,806,608     1,806,608 
---------------------------------------  ------------  ------------ 
 
 
                                  Country of      % of issued      Currency 
Name                             incorporation    share capital   denomination      GBP 
------------------------------  ---------------  --------------  -------------  ----------- 
 
PDS Biotechnology Corporation         USA            14.85%           US$         1,657,030 
CytoVale, Inc.                        USA            2.15%            US$           149,576 
Other                                                                                     2 
-----------------------------------------------  --------------  -------------  ----------- 
 
                                                                                  1,806,608 
 ----------------------------------------------  --------------  -------------  ----------- 
 

The shares in the above investments are not quoted in an active market and their fair value cannot be reliably measured. As such the investments have been measured at cost less accumulated impairment.

   8.         DERIVATIVE FINANCIAL ASSETS 
 
                  2015      2014 
                   GBP       GBP 
----------      --------  -------- 
 
 Warrants        100,159   100,159 
--------------  --------  -------- 
 

The Group have warrants to acquire equity shares in PDS Biotechnology Corporation at an agreed price at any time prior to 15 December 2016. The warrants have been valued using the Black-Scholes Model and a level 3 fair value hierarchy, given the unobservable data for volatility. This valuation has not changed in the year as the market value of the equity shares in PDS Biotechnology Corporation cannot be reliably measured.

This information is provided by RNS

The company news service from the London Stock Exchange

END

FR IFMTTMBMMTRF

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