TIDMNSCI

RNS Number : 8788K

NetScientific PLC

27 April 2020

27 April 2020

NetScientific plc

("NetScientific" or the "Group")

NetScientific Full Year Preliminary Results for the year ended 31 December 2019

London, UK - 27 April 2020 - NetScientific plc (AIM: NSCI), the transatlantic healthcare IP commercialisation Group, announces its full year preliminary results for the year ended 31 December 2019.

Financial highlights (including post-period end highlights)

-- Loss after tax of GBP4.9 million (2018: loss GBP9.4 million) reflects the portfolio business model

o Core portfolio companies develop and commercialise their proprietary technologies

o All portfolio companies are currently loss making

-- Cash used in operations reduced to GBP4.1 million (2018: GBP8.3 million) due to sale of Vortex and Wanda and lower head office costs

-- Cash and cash equivalents at HQ and portfolio companies of GBP3.5 million (2018: GBP2.9 million)

-- There were several Board changes during the year and post-period, including the Chairman and CEO.

Portfolio highlights (including post-period end highlights)

ProAxsis Ltd ("ProAxsis")

   --      Continued strong progress with revenue growth up 234% to GBP735k; cashflow breakeven 

o ProAxsis NEATstik ELISA kit sales up by 226%

o Contract with a large researcher conducting Phase 2 clinical trials in the last quarter of 2019

-- NEATstik(R) featured in a high-profile bronchiectasis study published in the European Respiratory Journal in 2019

   --      Short term loan and interest repaid to NetScientific plc 

-- Post-period, ProAxsis has revised its plans to take into account COVID-19 related delays and the opportunities being pursued.

Glycotest, Inc. ("Glycotest")

-- Completed $10.0 million series A funding round with Shanghai Fosun Pharmaceutical Co. Ltd, a leading Chinese healthcare group

o First and second tranches of $3.0 million each received on 14 February 2019 and 21 November 2019

-- Liver diagnostic test technology access granted to Fosun to enable Chinese regulatory filings and eventual commercialisation

   --      Completed proprietary assay analytical validation for HCC Panel at NMS Labs 

-- Initiated clinical validation trial for the HCC panel with 66 cases and 202 controls enrolled at year end

   --      Post-period, Glycotest has revised its plans to take into account COVID-19 related delays 

PDS Biotechnology Corporation ("PDS")

-- Completed merger with Edge Therapeutics on 18 March 2019, creating a NASDAQ listed immune-oncology biotechnology company developing novel products treating early-and late-stage cancer

   --      Collaboration with Merck in Phase 2 studies for PDS0101 

-- As part of a broader $12m raise, Net Scientific subscribed $650,000 for a further 500,000 shares of PDS common stock, total holding of 1,042,833 PDS common stock represents approximately 7.18% of the undiluted share capital.

-- Post-period, PDS announced an expanded infectious disease pandemic development program, including exploring novel vaccines for COVID-19 and universal influenza, in addition to its previously announced tuberculosis development collaboration with Farmacore Biotechnology

-- Post-period, PDS announced COVID-19 related delays to its Phase 2 PDS0101 clinical trial programme.

Vortex Biosciences, Inc. ("Vortex")

-- Sold on 22 March 2019 to Deeptech Disruptive Growth Investments Ltd ("Deeptech"), a special purpose vehicle "SPV" of EMV Capital Ltd, for total consideration of GBP113,999.

Wanda, Inc. ("Wanda")

   --      Sold on 22 March 2019 to Deeptech, for total consideration of GBP37,001. 

Commenting on the Group's 2019 full year results, Ian Postlethwaite, CEO/CFO of NetScientific, said:

" The Company's strategy remains to seek to maximise shareholder value from its core and other portfolio companies, which continue to perform and are making progress. During 2019, the Company carried out a review of all areas and significantly reduced the central function costs and headcount back to the essentials, thereby extending the Company's cash runway and using as much of the remaining cash as possible to maximise the value of the portfolio companies."

For more information, please contact:

 
  NetScientific                         Tel: +44 (0)20 3514 1800 
   Ian Postlethwaite , CEO/CFO 
  WHIreland (NOMAD, Financial Adviser   Tel: +44 (0)20 7220 1666 
   and Broker) 
   Chris Fielding / Darshan Patel 
  MO PR ADVISORY (Press Contact)        Tel: +44 (0)78 7644 4977 
   Mo Noonan 
 

About NetScientific

NetScientific PLC is a transatlantic healthcare IP commercialisation Group focused on technologies and companies that have the potential to treat chronic disease and significantly improve the health and well-being of people.

   For more information, please visit the website at   www.NetScientific.net 

CHAIRMAN'S AND CHIEF EXECUTIVE OFFICER'S STATEMENT

NetScientific PLC ("NetScientific", the "Group" or the "Company") is a transatlantic healthcare IP commercialisation group focused on technologies and companies that have the potential to treat chronic disease and significantly improve the health and well-being of people.

As announced in November 2018, the Group conducted a strategic review to maximise value for Shareholders, which included the potential sale of the Group or of a portfolio company. In early 2019, the Company had not received any offers for any of its portfolio companies nor was it in receipt of any approaches regarding a sale of the Company. The Board assessed all of its strategic options, including a potential cancellation from trading on AIM in order to reduce the Company's costs and to prolong the cash runway allowing for the maximum opportunity to realise cash from shareholdings in its investee companies. However, the general meeting to approve the cancellation was indefinitely adjourned.

Following this decision, in line with the circular sent to Shareholders on 15 February 2019, the Company's strategy has remained to seek to maximise shareholder value from its portfolio companies. During 2019, the Company carried out a review of all areas and significantly reduced the central function costs and headcount to the essentials, thereby extending the Company's cash runway and using as much of the remaining cash as possible to maximise the value of the portfolio companies.

In February and November 2019, Glycotest Inc. issued in total 11,822,605 shares to Fosun Pharmaceutical Co. Ltd ("Fosun Pharma"), a leading healthcare group based in China as part of a $10 million Series A financing deal , diluting the Group's interest in Glycotest by 21.85% to 65.65%, a deemed disposal of a stake in a subsidiary. Since receiving the funding, Glycotest has increased expenditure on clinical trial preparations, administration and research and development on the path to commercialisation.

In March 2019, the Company completed a GBP0.15m cash sale to Deeptech Disruptive Growth Investments Ltd ("Deeptech"), a Special Purpose Vehicle of EMV Capital Ltd, of its interests in Vortex and Wanda, together with any outstanding loans and convertible loan notes owed to the Company by Wanda or Vortex. Immediately prior to completion, NetScientific was interested in approximately 95.0% and 70.8% of the issued shares of common stock of Vortex and Wanda, respectively, and 100% of the Preferred Shares of Wanda. The results of Vortex and Wanda included within the consolidated accounts of NetScientific amounted, to a gain of GBP0.6 million and a loss of GBP1.9 million, respectively, and the net assets of Vortex and Wanda at the same date were GBP0.3 million and GBP0.1 million, respectively net of intercompany balances. The loss for the year by the Vortex and Wanda discontinued operations was GBP1.3 million (2018: GBP5.4 million) reducing the operational funding requirement of the Group substantially going forward as look to preserve cash.

PDS has seen its fair value decline during 2018, 2019 and into early 2020 due primarily to a weak market for smaller listed companies and specifically to a stock overhang and a lack of new clinical trial information to drive the value forward. At year end PDS's share price was $2.65 per share valuing our investment at GBP1.1 million (2018: GBP2.6 million). The Board continues to believe that PDS has strong prospects and participated post year end in a $12m raise to acquire a further 500,000 shares for $650,000 taking its total holding to 1,042,000, representing approximately 7.18% of the undiluted share capital. This provides PDS with funding to initiate Phase 2 trials.

During the period there has been a significant reshaping of the Board. Francois Martelet resigned as a Director on 30 April 2019. On 14 October 2019, Dr. Ilian Iliev joined the Board as a non-executive director. Barry Wilson retired from the Board on 13 December 2019 following seven years as Non-Executive Director and John Clarkson joined the Board as Non-Executive Director. On the 15 January 2020, it was announced that Ian Postlethwaite had served six months' notice to step down as CEO, CFO and Company Secretary during April 2020. On 31 March 2020, it was announced that Sir Richard Sykes would retire from the Board following nine years as Chairman. John Clarkson, took over as the Chairman of the Board with immediate effect. It is expected that Dr. Ilian Iliev, currently a Non-Executive Director, will become a part time Executive Director and interim CEO, and Stephen Crowe, currently Financial Controller, will take over as interim CFO.

The Group is following the latest health authority and government advice in light of Covid-19. T he primary focus is the health, wellbeing and safety of all its employees and local communities. The Group has reviewed all the major budgeted assumptions and sensitivities and drawn up cash preservation plans in case revenue does not continue as planned, or it faces delays in planned payments from third parties. It has initiated further cost saving plans across the Group and delayed expenditure where possible, until there is more clarity on the financial impact of the pandemic. In some cases, the crisis restrictions will delay trials and programs, which will defer expenditure and thus extend the cash runway. Also, there may be opportunities to take advantage of the financial support measures and divert effort and resources to address Covid-19 issues and generate new revenue streams, further ensuring the Group has options and cash for at least the next twelve months.

CHAIRMAN'S AND CHIEF EXECUTIVE OFFICER'S STATEMENT continued

Portfolio Review

ProAxsis Ltd ("ProAxsis")

ProAxsis is a medical diagnostics company, based in Northern Ireland, developing a range of products for the capture, detection and measurement of active protease biomarkers of disease. The company is primarily focused on chronic respiratory diseases such as COPD and bronchiectasis but has recently demonstrated the adaptability of its technology for use in other clinical areas such as oncology.

ProAxsis has made strong operational progress during 2019 and has now reached cashflow breakeven based on higher revenue up 234% at GBP735k versus 2018. This increase in revenue is mainly due to the increase of ProAxsis NEATstik ELISA kit sales, up by 226%, and a large researcher conducting Phase 2 clinical trials in the last quarter of 2019. The outlook for the company in 2020 is positive, with several contracts already in place with global pharmaceutical companies.

The company's lead product, NEATstik(R), was featured in a high-profile bronchiectasis study published in the European Respiratory Journal in May 2019, which demonstrated encouraging data on its ability to monitor bacterial infections in real time in patients suffering from lung diseases.

In March 2020, ProAxsis repaid the GBP0.1 million loan to NetScientific plus interest from 2019.

NetScientific's shareholding in ProAxsis is 56.5% (fully diluted being 54.0%) and as at 31 December 2019, the Group had invested GBP2.1 million (2018: GBP2.1 million).

Grant funding received to develop both the underlying technology and new applications has exceeded GBP1.2 million (2018: GBP1.2 million).

Glycotest, Inc. ("Glycotest")

Glycotest is a US-based liver diagnostics start-up company seeking to commercialise new and unique blood tests for life threatening liver cancers and fibrosis-cirrhosis.

On 14 February 2019 and 21 November 2019, respectively Glycotest received the first and second tranches of $3m each of the $10 million Series A financing from Fosun Pharmaceutical Co. Ltd ("Fosun Pharma"), a leading healthcare group based in China. As part of the Series A raise Glycotest granted access to its liver diagnostic test technology to Fosun during 2019 to enable the preparation of regulatory filings and eventual commercialization in China.

The company has continued to make good progress. During 2019, Glycotest completed proprietary assay analytical validation at NMS Labs for the HCC panel, and initiated clinical validation trial for the Panel with 14 sites open to enrolling patients and with a further six sites in the process of signing patients. As at 31 December 2019, 66 cases and 202 controls were enrolled. Glycotest also initiated fibrosis and cholangiocarcinoma assay projects during 2019. These development projects continue in 2020.

Glycotest also appointed a new reagent manufacturer, Rockland Immunochemicals, in Q3 2019.

Grant funding received to develop the underlying technology, prior to Glycotest's formation, was GBP5.9 million.

NetScientific's shareholding in Glycotest is 65.6% (2018: 87.5%), fully diluted being 51.5% (2018: 51.5%) and as at 31 December 2019, the Group had invested GBP3.9 million (2018: GBP3.9 million).

CHAIRMAN'S AND CHIEF EXECUTIVE OFFICER'S STATEMENT continued

PDS Biotechnology Corporation

PDS is a clinical stage immunotherapy company developing a next generation of simpler, safer and more effective immunotherapies for cancer and infectious diseases. It continued to see strong progress with its T-cell activating technology platform, Versamune(R), which combines three critical attributes for an effective immunotherapy: T-cell induction, reduced tumour suppression and priming of a potent anti-tumour response without the conventional associated toxicities.

In November 2018, PDS entered into a merger agreement with Edge Therapeutics, which completed on 14 March 2019, to form a Nasdaq-Listed Clinical-Stage Cancer Immunotherapy company. The merger created a publicly traded immune-oncology biotechnology company (now re-named PDS Biotechnology Corporation) developing novel products treating early-and late-stage cancer. This follows positive phase I and 2 clinical data on its lead product candidate, PDS0101, indicating immunotherapeutic anti-cancer activity and favourable safety profile in early stage cervical cancer. PDS plans to initiate multiple phase 2b and 3 clinical trials of PDS0101 in HPV-associated cancers.

The year-end share price has been used to re-value the Group's equity holding therein. The Company's ownership of the enlarged PDS Biotechnology Corporation, trading on Nasdaq under the ticker PDSB, on a fully diluted basis is 8.15%. At year end PDS's share price was $2.65 per share valuing our investment at GBP1.1 million (2018: GBP2.6 million). As at 22 April 2020 the share price is $0.91 per share valuing the investment at GBP0.8m.

In May 2019, PDS announced a peer-reviewed publication supporting the novel mechanisms of action of its proprietary Versamune(R) platform in cancer immunotherapy. The article "Antigen Priming with Enantiospecific Cationic Lipid Nanoparticles Induces Potent Antitumor CTL Responses through Novel Induction of a Type I IFN Response" was published online on 3 May 2019 in the Journal of Immunology, and described the way PDS' Versamune(R) platform recruits and activates killer T-cells to recognize and effectively attack cancer cells while simultaneously making cancer cells more susceptible to T-cell attack.

In October 2019, PDS announced that it would be collaborating with Merck in Phase 2 studies for PDS0101 in combination with Merck's anti-PD-1 therapy, KEYTRUDA(R) (pembrolizumab), as a first line treatment in patients with recurrent or metastatic head and neck cancer and high-risk human papillomavirus-16 (HPV16) infection. The planned clinical trial is evaluating the efficacy and safety of the combination as a first-line treatment and was initiated in the first quarter of 2020.

The Group has invested GBP2.7 million in PDS to 31 December 2019. On the balance sheet the investment in PDS is shown as equity investments classified as fair value through other comprehensive income (FVTOCI).

On 12 February 2020, it was announced that PDS had issued new shares of common stock to raise gross proceeds of approximately US$12 million ("New Issue"). NetScientific plc subscribed $650,000, for 500,000 shares of PDS common stock in the new issue. NetScientific now owns approximately 7.18% of the undiluted share capital.

On 9 April 2020 PDS appointed Dr. Ilian Iliev to its Board of Directors.

On 16 April 2020 PDS announced an expanded infectious disease pandemic development program, including novel vaccines for COVID-19 and universal influenza, in addition to its previously announced tuberculosis development collaboration with Farmacore Biotechnology. PDS also announced that initiation of its multi-center Phase 2 VERSATILE-002 trial for PDS0101 in advanced/metastatic head and neck cancer had been delayed due to the severe adverse impact on clinical trial operations from the COVID-19 pandemic.

Vortex Biosciences, Inc. ("Vortex")

Vortex Biosciences, Inc. was sold to Deeptech on 22 March 2019 for total consideration of GBP112,999, being GBP1 for the shares and GBP112,998 for the transfer of the debt.

NetScientific shareholding in Vortex was 95.0%, fully diluted being 66.1% and as of 31 December 2019, the Group had invested GBP21.4 million (2018: GBP21.4 million).

Wanda, Inc. ("Wanda")

Wanda, Inc. was sold to Deeptech on 22 March 2019 for total consideration of GBP37,001, being GBP1 for the shares and GBP37,000 for the preferred stock and debt.

NetScientific's shareholding in Wanda was 70.8%, fully diluted being 61.8% and as at 31 December 2019, the Group had invested GBP11.6 million (2018: GBP11.6 million).

CHAIRMAN'S AND CHIEF EXECUTIVE OFFICER'S STATEMENT continued

Early stage Investments Portfolio

During the year, the Group reviewed its five early stage investments (the 'Early Stage Portfolio'). Limited investment has been made to date, mostly in the form of convertible loans. The five assets are in the following companies CytoVale, Inc., Epibone, Inc., Longevity Biotech, Inc., G-Tech, Inc., and Nemitra, Inc. Only two of the five early stage investments, CytoVale and Epibone currently have any material value. Of note from the Early Stage Portfolio:

Cytovale, a clinical stage company using cell mechanics and machine learning to revolutionise diagnostics starting with sepsis, announced a preferred Series B funding round in 2019 valuing the company at $50m, decreasing slightly the value of the NetScientific investment to GBP0.4m.

Epibone, a ground-breaking research company that transforms skeletal repair by remodelling stem cells into a personalized bone graft ready for implantation, announced a Series A funding round in January 2020 raising $8 million. NetScientific's convertible loan note and accrued interest valued at GBP0.3m at year end converted into preferred shares valued at GBP0.3m on the closing of the financing. and values the Company post investment at $35 million. NetScientific is in active dialogue regarding developments.

On the balance sheet (as explained in note 3) the investment in Cytovale is shown within equity investments classified as FVTOCI whilst the other early stage investment portfolios are all shown within financial assets classified as FVTPL as warrants and convertible loan notes at a fair value of GBP0.3m which now relates to a single convertible loan note investment in Epibone.

Finance

For the year, the Group made a loss of GBP4.9 million (2018: GBP9.4 million), split between continuing and discontinued operations as follows:

 
 -   Continuing operations     GBP3.6 million (2018: 
                                GBP4.0 million) 
 -   Discontinued operations   GBP1.3 million (2018: 
                                GBP5.4 million) 
 

The loss reflects the business model where the core portfolio companies are mainly subsidiaries. These companies are commercialising or still developing their technologies and are all currently loss making.

Cash

Cash on the balance sheet as at 31 December 2019 was GBP3.5 million (2018: GBP2.9 million). Cash used in operations in 2019, was GBP4.1 million (2018: GBP8.3 million). Group companies are not expected to require any further funding hereafter in 2020. ProAxsis required a short loan in January 2020 which has now been repaid. GBP1.2m is held in the Company, giving it and the Group enough cash to operate until the end of 2021. The cash held within subsidiary Glycotest, Inc., of GBP2.2m (2018: GBP0.1m) is not freely available for use within the wider group as it would need the consent of a 40% minority shareholder.

In February 2020, NetScientific plc subscribed for $650,000 of PDS common stock in its new issue. Upon completion of the new issue, NetScientific owns approximately 7.18% of the undiluted share capital of PDS. NetScientific had cash to fund this investment, however, on 7 April 2020 for prudent financial management, the Group entered into an 18-month secured GBP700,000 line of credit with the Beckman Group. The facility, which incurs interest of 10.0% pa on drawn amounts and 3.0% pa on undrawn amounts and had an arrangement fee of 1%, can be extended by mutual agreement for an additional six months and is secured on the whole of NetScientific's interest in PDS.

Going concern

The Directors have prepared and reviewed budget cashflows which were approved by the Board of Directors in the Board meeting of 5 December 2019, and further reviewed at the Board meeting on 18 March 2020 for the impact of Covid-19 and subsequently approved on 25 March 2020. The budgeted cash flows included a number of implemented cash saving initiatives, including:

a) significantly reducing the Company's central cost base by reductions in headcount, closing the office at 6 Bevis Marks London at the end of March 2019 and reviewing all expenditure commitments;

b) selling Vortex and Wanda for net proceeds of GBP0.15 million on 22 March 2019 and consequently reducing the operational cost base and funding requirement of the Group;

c) allocating the remaining cash to manage the remaining portfolio companies which the board believes provide the most realistic prospects of delivering shareholder returns within the anticipated lifespan of the Company; and

   d)      making a planned partial drawdown of the GBP700k line of credit towards the end of 2020. 

The Group has reviewed the major budgeted assumptions and sensitivities in light of Covid-19 and drawn up cash preservation plans in case revenue does not continue as planned, or it faces delays in planned payments from third parties. It has initiated further cost saving plans across the Group and delayed expenditure where possible, until there is more clarity on the financial impact of the pandemic. In some cases, the crisis restrictions will delay trials and programs, which will defer expenditure and thus extend the cash runway. Also, there may be opportunities to take advantage of the financial support measures and divert resources to support the Covid-19 effort and generate new revenue streams, further ensuring the Group has options and cash for at least the next twelve months.

The Going concern status of the group is dependent on meeting its forecast including generating revenues, receiving planned payments from third parties and achieving planned cost savings. In the event the Group is unable to meet its forecasts it will need to raise further finance. These events or conditions indicate that a material uncertainty exists that may cast significant doubt on the Group and the company's ability to continue as a going concern.

The financial statements do not include any adjustments that would be necessary if the group or company was unable to continue as a going concern.

CHAIRMAN'S AND CHIEF EXECUTIVE OFFICER'S STATEMENT continued

Board changes

There were four Board changes during the year (2018: 1).

Francois Martelet resigned as a Director on 30 April 2019. On 14 October 2019 Dr. Ilian Iliev joined the Board as a non-executive director. Barry Wilson retired from the Board on 13 December 2019 following seven years as Non-Executive Director, and John Clarkson joined the Board as Non-Executive Director. On 15 January 2020 it was announced that Ian Postlethwaite had served six months' notice to step down as CEO, CFO and Company Secretary. On 31 March 2020 it was announced that Sir Richard Sykes would retire from the Board following nine years as Chairman. John Clarkson, took over as the Chairman of the Board with immediate effect. It is expected that Dr. Ilian Iliev, currently a Non-Executive Director, will become a part time Executive Director and interim CEO. Finally, it is anticipated that Stephen Crowe, currently Financial Controller, will take over as interim CFO during April 2020.

Summary and Outlook

The Board believes that the portfolio companies continue to hold great potential which the Group will look to unlock. The Company's strategy remains to maximise shareholder value from the portfolio companies by:

a) reducing the Company's central functions and costs significantly such that as much of the remaining cash as possible can be allocated to the portfolio companies and their active management; and

b) assessing the funding requirements of each portfolio company against its prospects of generating a shareholder return.

 
 John Clarkson                         Ian Postlethwaite 
 Non-Executive Director and Chairman   Chief Executive Officer/Chief Financial 
                                        Officer 
 24 April 2020                         24 April 2020 
 

Consolidated Income Statement

For the year ended 31 December 2019

 
                                                     2019        2018 
 Continuing Operations                  Notes    GBP000's    GBP000's 
 
   Revenue                                            735         245 
 Cost of sales                                      (117)        (78) 
-------------------------------------  ------  ----------  ---------- 
 
   Gross profit                                       618         167 
 
 Other operating income                                76         101 
 Research and development costs                   (1,979)       (524) 
 General and administrative costs                 (2,079)     (2,821) 
 Other costs                                        (269)     (1,029) 
 
   Loss from operations                           (3,633)     (4,106) 
 
   Finance income                                      21          47 
 Finance expense                                     (22)        (12) 
 
   Loss before taxation                           (3,634)     (4,071) 
 
   Income tax credit                                   88          73 
-------------------------------------  ------  ----------  ---------- 
 
   Loss for the year from continuing 
   operations                                     (3,546)     (3,998) 
 
 
 Discontinued Operations 
-------------------------------------  ------  ----------  ---------- 
 
 Loss for the year from discontinued 
  operations                                      (1,326)     (5,405) 
-------------------------------------  ------  ----------  ---------- 
 
   Total loss for the year                        (4,872)     (9,403) 
-------------------------------------  ------  ----------  ---------- 
 
 
 Owners of the parent                             (4,491)     (8,328) 
 Non-controlling interests                          (381)     (1,075) 
-------------------------------------  ------  ----------  ---------- 
 
                                                  (4,872)     (9,403) 
 
 Basic and diluted loss per share 
  from continuing and discontinued 
  operations attributable to owners 
  of the parent during the year:           5 
 Continuing operations                             (4.3p)      (4.8p) 
 Discontinued operations                           (1.4p)      (6.2p) 
 From loss for the year                            (5.7p)     (11.0p) 
-------------------------------------  ------  ----------  ---------- 
 
 

Consolidated Statement OF Comprehensive Income

For the year ended 31 December 2019

 
                                               Notes         2019         2018 
                                                         GBP000's     GBP000's 
--------------------------------------------  -------  ----------  ----------- 
 
   Loss for the year                                      (4,872)      (9,403) 
 Other comprehensive income: 
 Exchange differences on translation 
  of foreign operations                                      (56)           94 
 Change in fair value of equity investments 
  classified as FVTOCI                                    (1,340)      (3,863) 
 
   Total comprehensive loss for the year                  (6,268)     (13,172) 
-----------------------------------------------------  ----------  ----------- 
 
 
 Attributable to: 
 Owners of the parent            (5,891)     (11,810) 
 Non-controlling interests         (377)      (1,362) 
----------------------------  ----------  ----------- 
 
                                 (6,268)     (13,172) 
 ---------------------------  ----------  ----------- 
 

Consolidated Statement of Financial Position

As at 31 December 2019

 
                                               Notes        2019        2018 
                                                        GBP000's    GBP000's 
--------------------------------------------  ------  ----------  ---------- 
 Assets 
 Non-current assets 
 Property, plant and equipment                               128         169 
 Right-of-use assets                             6           221           - 
 Equity investments classified as 
  FVTOCI*                                        8         1,468       2,768 
 Financial assets classified as FVTPL**          9           262         297 
 Total non-current assets                                  2,079       3,234 
--------------------------------------------  ------  ----------  ---------- 
 
 Current assets 
 Inventory                                                    30          37 
 Trade and other receivables                                 603         445 
 Cash and cash equivalents                                 3,453       2,911 
--------------------------------------------  ------  ----------  ---------- 
                                                           4,086       3,393 
 
 Assets in disposal groups classified 
  as held for sale                                             -         569 
--------------------------------------------  ------  ----------  ---------- 
 Total current assets                                      4,086       3,962 
--------------------------------------------  ------  ----------  ---------- 
 
   Total assets                                            6,165       7,196 
--------------------------------------------  ------  ----------  ---------- 
 
   Liabilities 
   Current liabilities 
 Trade and other payables                                  (623)       (668) 
 Lease liabilities                               6          (30)           - 
 Loans and borrowings                                      (163)       (140) 
--------------------------------------------  ------  ----------  ---------- 
                                                           (816)       (808) 
 
 Liabilities directly associated 
  with assets in disposal groups classified 
  as held for sale                                             -       (158) 
--------------------------------------------  ------  ----------  ---------- 
 Total current liabilities                                 (816)       (966) 
--------------------------------------------  ------  ----------  ---------- 
 
   Non-current liabilities 
 Lease liabilities                               6         (194)           - 
 Loans and borrowings                                       (50)        (60) 
 Total non-current liabilities                             (244)        (60) 
--------------------------------------------  ------  ----------  ---------- 
 
   Total liabilities                                     (1,060)     (1,026) 
--------------------------------------------  ------  ----------  ---------- 
 
   Net assets                                              5,105       6,170 
--------------------------------------------  ------  ----------  ---------- 
 
 Issued capital and reserves 
  Attributable to the parent 
 Called up share capital                                   3,928       3,928 
 Share premium account                                    58,006      58,006 
 Capital reserve account                                     237         237 
 Equity investment reserve                               (1,408)        (68) 
 Foreign exchange reserve                                  1,384       1,444 
 Retained earnings                                      (56,681)    (51,442) 
--------------------------------------------  ------  ----------  ---------- 
 
   Equity attributable to the owners 
   of the parent                                           5,466      12,105 
 
   Non-controlling interests                               (361)     (5,935) 
--------------------------------------------  ------  ----------  ---------- 
 
   Total equity                                            5,105       6,170 
--------------------------------------------  ------  ----------  ---------- 
 

*Fair value through other comprehensive income

**Fair value through profit and loss

Consolidated Statement of Changes in Equity

As at 31 December 2019

 
                                                     Shareholders' equity 
                                                                            Foreign 
                                                                           exchange 
                                                       Equity                   and 
                     Share      Share    Capital   investment   Retained    capital                 Non-controlling      Total 
                   capital    premium    reserve      reserve   earnings    reserve         Total         interests     equity 
                  GBP000's   GBP000's   GBP000's     GBP000's   GBP000's   GBP000's      GBP000's          GBP000's   GBP000's 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 1 January 
  2018               3,452     53,839        237            -   (43,220)      1,063        15,371           (4,573)     10,798 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 Change on 
  initial 
  application 
  of IFRS 9 
  Financial 
  Instruments 
  (see note 
  1)                     -          -          -        3,795          -          -         3,795                 -      3,795 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 Balance at 
  1 January 
  2018 (as 
  restated)          3,452     53,839        237        3,795   (43,220)      1,063        19,166           (4,573)     14,593 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 Loss for the 
  period                 -          -          -            -    (8,328)          -       (8,328)           (1,075)    (9,403) 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 Other 
 comprehensive 
 income - 
 Foreign 
  exchange 
  differences            -          -          -            -          -        381           381             (287)         94 
 Change in 
  fair value 
  during the 
  year                   -          -          -      (3,863)          -          -       (3,863)                 -    (3,863) 
 Total 
  comprehensive 
  income                 -          -          -      (3,863)    (8,328)        381      (11,810)          (1,362))   (13,172) 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 Share capital 
  issued               476      4,524          -            -          -          -         5,000                 -      5,000 
 Change in 
  fair value 
  of equity 
  investments 
  classified 
  as FVTOCI              -      (357)          -            -          -          -         (357)                 -      (357) 
 Share-based 
  payments               -          -          -            -        106          -           106                 -        106 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 31 December 
  2018               3,928     58,006        237         (68)   (51,442)      1,444        12,105           (5,935)      6,170 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 Loss for the 
  period                 -          -          -            -    (4,491)          -       (4,491)             (381)    (4,872) 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 Other 
 comprehensive 
 income - 
 Foreign 
  exchange 
  differences            -          -          -            -          -       (60)          (60)                 4       (56) 
 Change in 
  fair value 
  of equity 
  investments 
  classified 
  as FVTOCI              -          -          -      (1,340)          -          -       (1,340)                 -    (1,340) 
 Total 
  comprehensive 
  income                 -          -          -      (1,340)    (4,491)       (60)       (5,891)             (377)    (6,268) 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 Decrease in 
  subsidiary 
  shareholding           -          -          -            -      2,668          -         2,668             1,677      4,345 
 Disposal of 
  subsidiaries           -          -          -            -    (3,469)                  (3,469)             4,274        805 
 Share-based 
  payments               -          -          -            -         53          -            53                 -         53 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 31 December 
  2019               3,928     58,006        237      (1,408)   (56,681)      1,384         5,466             (361)      5,105 
---------------  ---------  ---------  ---------  -----------  ---------  ---------  ------------  ----------------  --------- 
 
 

Consolidated Statement of Cash Flows

As at 31 December 2019

 
                                          Notes         2019        2018 
                                                    GBP000's    GBP000's 
---------------------------------------  -------  ----------  ---------- 
 Cash flows from operating activities 
 Loss after income tax including 
  discontinued operations                            (4,872)     (9,403) 
 Adjustments for: 
 Depreciation of property, plant 
  and equipment                                           42         262 
 Depreciation of right-of-use assets                      32           - 
 Estimated credit losses on trade                         56           - 
  receivables 
 Impairment of property, plant & 
  equipment and inventories                                -         977 
 Loss on disposal of property, plant                       4           - 
  and equipment 
 Loss on disposal of subsidiaries                        703           - 
 Fair value movement during the year 
  on convertible debt                                      -         230 
 Release of loan provision                                 -        (40) 
 Share-based payments                                     53         132 
 Foreign exchange gains                                   23        (65) 
 Finance income                                         (21)        (47) 
 Finance costs                                            22          12 
 Tax credit                                             (88)        (73) 
                                                     (4,046)     (8,015) 
 Changes in working capital 
 Decrease/(increase) in inventory                          7       (296) 
 (Increase)/decrease in trade and 
  other receivables                                    (130)       (136) 
 Increase/(decrease) in trade and 
  other payables                                        (26)          24 
------------------------------------------------  ----------  ---------- 
 Cash used in operations                             (4,195)     (8,423) 
------------------------------------------------  ----------  ---------- 
 Income tax received                                      72         142 
------------------------------------------------  ----------  ---------- 
 Net cash used in operating activities               (4,123)     (8,281) 
------------------------------------------------  ----------  ---------- 
 Cash flows from investing activities 
 Disposal of discontinued operations,                     34           - 
  net of cash disposed of 
 Purchase of property, plant and 
  equipment                                              (6)       (112) 
 Proceeds from sale of property, 
  plant and equipment                                      -           1 
 Interest received                                         7          23 
 Net cash from/(used in) investing 
  activities                                              35        (88) 
------------------------------------------------  ----------  ---------- 
 
 
 
 Cash flows from financing activities 
 Proceeds received on change in stake            4,345         - 
  in subsidiary 
 Lease payments                            6      (38)         - 
 Repayment from borrowings                           -      (10) 
 Proceeds from loans                                 -        39 
 Proceeds from share issue                           -     5,000 
 Share issue cost                                    -     (357) 
----------------------------------------      --------  -------- 
 Net cash from financing activities              4,307     4,672 
----------------------------------------      --------  -------- 
 Increase/(decrease) in cash and 
  cash equivalents                                 219   (3,697) 
 Cash and cash equivalents at beginning 
  of year                                        3,316     6,868 
 Cash in disposal groups classified 
  as held for sale                                   -     (405) 
 Exchange differences on cash and 
  cash equivalents                                (82)       145 
----------------------------------------      --------  -------- 
 
   Cash and cash equivalents at end 
   of year                                       3,453     2,911 
----------------------------------------      --------  -------- 
 

Notes to the Financial Information for the Year Ended 31 December 2018

   1.              GENERAL INFORMATION 

The Company is a public limited company incorporated on 12 April 2012 and domiciled in England with registered number 08026888 and its shares are listed on the Alternative Investment Market (AIM) of the London Stock Exchange. The address of the registered office is Anglo House, Bell Lane Office Village, Bell Lane, Amersham, Buckinghamshire HP6 6FA.

   2.             BASIS OF PREPARATION 

The preliminary results of the year ended 31 December 2019 have been extracted from audited accounts which have not yet been delivered to Companies House.

The financial information set out in this announcement does not constitute statutory accounts for the year ended 31 December 2019.

The report of the auditors on the statutory accounts for the year ended 31 December 2019 did not contain a statement under Section 498 of the Companies Act 2006 but drew attention to a material uncertainty in respect of going concern and included the following wording in that respect;

Material uncertainty related to going concern

As set out in note 3, the group is loss generating and is reliant upon fundraising and cost savings in order to obtain the resources necessary to continue. The Going concern status of the group is dependent on meeting its forecast including generating revenues, receiving planned payments from third parties and achieving planned cost savings. In the event the group is unable to meet its forecasts it will need to raise further finance. These events or conditions indicate that a material uncertainty exists that may cast significant doubt on the group and the company's ability to continue as a going concern.

These events or conditions, along with other matters as set out in Note 3, indicate that a material uncertainty exists which may cast significant doubt over the Group's ability to continue as a going concern. Our opinion is not modified in respect of this matter.

The financial statements for the year ended 31 December 2019 included in this announcement were authorised for issue in accordance with a resolution of the Board of Directors on 24 April 2020.

   3.             GOING CONCERN 

The Directors have prepared and reviewed budget cashflows which were approved by the Board of Directors in the Board meeting of 5 December 2019, and further reviewed at the Board meeting on 18 March 2020 for the impact of Covid-19 and subsequently approved on 25 March 2020. The budgeted cash flows included a number of implemented cash saving initiatives, including:

a) significantly reducing the Company's central cost base by reductions in headcount, closing the office at 6 Bevis Marks London at the end of March 2019 and reviewing all expenditure commitments;

b) selling Vortex and Wanda for net proceeds of GBP0.15 million on 22 March 2019 and consequently reducing the operational cost base and funding requirement of the Group;

c) allocating the remaining cash to manage the remaining portfolio companies which the board believes provide the most realistic prospects of delivering shareholder returns within the anticipated lifespan of the Company; and

   d)      making a planned partial drawdown of the GBP700k line of credit towards the end of 2020. 

The Group has reviewed the major budgeted assumptions and sensitivities in light of Covid-19 and drawn up cash preservation plans in case revenue does not continue as planned, or it faces delays in planned payments from third parties. It has initiated further cost saving plans across the Group and delayed expenditure where possible, until there is more clarity on the financial impact of the pandemic. In some cases, the crisis restrictions will delay trials and programs, which will defer expenditure and thus extend the cash runway. Also, there may be opportunities to take advantage of the financial support measures and divert resources to support the Covid-19 effort and generate new revenue streams, further ensuring the Group has options and cash for at least the next twelve months.

The Going concern status of the group is dependent on meeting its forecast including generating revenues, receiving planned payments from third parties and achieving planned cost savings. In the event the Group is unable to meet its forecasts it will need to raise further finance. These events or conditions indicate that a material uncertainty exists that may cast significant doubt on the Group and the company's ability to continue as a going concern.

The financial statements do not include any adjustments that would be necessary if the group or company was unable to continue as a going concern.

   4.             SIGNIFICANT ACCOUNTING POLICIES 

The Group financial statements have been prepared in accordance with International Financial Reporting Standards as adopted by the European Union as they apply to the financial statements of the Group for the year ended 31 December 2019. The principal accounting policies adopted in the preparation of the financial information are set out below. The policies have been consistently applied to all the years presented.

While the financial information included in this preliminary announcement has been prepared in accordance with IFRS, this announcement does not in itself contain sufficient information to comply with IFRS. The Group expects to publish full financial statements that comply with IFRS by 1 May 2020.

   5.             LOSS PER SHARE 

The basic and diluted loss per share is calculated by dividing the loss for the financial year by the weighted average number of ordinary shares in issue during the year. Potential ordinary shares from outstanding options at 31 December 2019 of 3,475,984 (2018: 2,782,651) are not treated as dilutive as the entity is loss making.

 
                                              2019         2018 
                                          GBP000's     GBP000's 
-------------------------------------  -----------  ----------- 
 Loss attributable to equity holders 
  of the Company 
 
 Continuing operations                       3,409        3,648 
 Discontinued operations                     1,082        4,680 
                                       -----------  ----------- 
 Total                                       4,491        8,328 
                                       -----------  ----------- 
 
 Number of shares 
 Weighted average number of ordinary 
  shares in issue                       78,561,866   75,796,048 
 
 
   6.             IFRS 16 LEASES 

Effective 1 January 2019, IFRS 16 has replaced IAS 17 Leases and IFRIC 4 Determining whether an Arrangement Contains a Lease.

IFRS 16 provides a single lessee accounting model, requiring the recognition of assets and liabilities for all leases, together with options to exclude leases where the lease term is 12 months or less, or where the underlying asset is of low value. The Group does not have significant leasing activities acting as a lessor.

Transition Method and Practical Expedients Utilised

On adoption of IFRS 16, the Group recognised right-of-use assets and lease liabilities in relation to leases of office space, which had previously been classified as operating leases.

The judgement that the Group was reasonably certain to extend for the full term of the lease beyond the contractual breaks in the third, fifth and seventh years of the lease have made a material difference to the carrying value of the asset/liability. The impact of this judgement is to increase the initial asset/liability amounts by GBP216k, GBP181k and GBP114k respectively.

The lease liabilities were measured at the present value of the remaining lease payments, discounted using the incremental borrowing rate as at 1 January 2019. The incremental borrowing rate is the rate at which a similar borrowing could be obtained from an independent creditor under comparable terms and conditions. The rate applied was 3.5%.

Transition to IFRS 16

The table below shows the impact due to the transition to IFRS 16 and the initial effect on the balance sheet as at 1 January 2019.

 
                                           2019        2018 
                                       GBP000's    GBP000's 
-----------------------------------  ----------  ---------- 
 Right-of-use asset 
 
 Addition 1 January 2019                    253           - 
 Less: 
 Amortisation during the period            (32)           - 
                                     ----------  ---------- 
 Balance at 31 December 2019                221           - 
                                     ----------  ---------- 
 
 Lease Liability 
 
 Initial recognition 1 January 2019       (253)           - 
 Add: 
 Payments                                    38           - 
 Less: 
 Interest charge during the period          (9)           - 
 Balance at end of period                 (224)           - 
                                     ----------  ---------- 
 
 Split as follows: 
 
 Current Liability                         (30)           - 
 Long Term Liability                      (194)           - 
                                          (224)           - 
                                     ----------  ---------- 
 

Instead of recognising an operating expense for its operating lease payments, the Group will instead recognise interest on its lease liabilities and amortisation on its right-of-use assets. This will increase the reported total loss for the year by the amount of its current operating lease cost, which for the year ended 31 December 2018 was GBP54k for continuing operations. Due to the short terms of the Group's leases, approximately there will only be a nominal charge to interest of approximately GBP9k with the rest of the charge being recognised as depreciation of GBP32k. There are several short-term leases where the lease commitment is under six months in length where the Group will continue to spread the lease payments on a straight-line basis over the lease term.

   7.             INVESTMENTS IN SUBSIDIARY UNDERTAKINGS 

The Group had the following subsidiaries at 31 December 2019:

 
                                                                                          Proportion        Proportion 
                                                                                        of ownership      of ownership 
                                                       Proportion       Proportion          interest          interest 
                                                               of               of           held by           held by 
                                                        ownership        ownership   non-controlling   non-controlling 
                      Primary         Country of         interest         interest         interests         Interests 
                      trading      incorporation   at 31 December   at 31 December    at 31 December    at 31 December 
Name                  address    or registration             2019             2018              2019              2018 
------------------  ---------  -----------------  ---------------  ---------------  ----------------  ---------------- 
 
NetScientific 
 UK Limited            (a)                    UK             100%             100%                 -                 - 
ProAxsis Ltd * 
 (i)                   (b)                    UK            56.5%            56.5%             43.5%             43.5% 
 
NetScientific 
 America, Inc.         (c)                   USA             100%             100%                 -                 - 
Vortex 
 BioSciences, 
 Inc. ** (i)           (d)                   USA                -              95%                 -                5% 
Wanda, Inc. ** 
 (i)                   (e)                   USA                -            70.8%                 -             29.2% 
Glycotest, Inc. 
 (i), (ii)             (f)                   USA            65.6%            87.5%             34.4%             12.5% 
 

For all undertakings listed above, the country of operation is the same as its country of incorporation or registration.

   *        Held via an intermediate holding company. 
   **      Sold to Deeptech in March 2019, a SPV of EMV Capita Ltd for total consideration of GBP150k. 

All of the ownerships shown above relate to ordinary shareholdings.

(i) Options have been issued by ProAxsis Ltd and Glycotest, Inc. which if exercised would dilute the Company's shareholding by 3% and 14% respectively.

(ii) Following issue of further shares during the year the Group's interest was reduced to 77.5% on 14 February 2019 and then to 65.6% on the 21 November 2019.

   (a)   Anglo House, Bell Lane Office Village, Bell Lane, Amersham, Buckinghamshire, HP6 6FA 

(b) Unit 1B, Concourse Building, 3, Catalyst Inc, Titanic Quarter, 6 Queens Road, Belfast, BT3 9DT, Northern Ireland

(c) 1650 Market Street, Suite 4900, Philadelphia, Pennsylvania, 19103-7300, United States of America

   (d)   5627 Stoneridge Drive, Suite 312, Pleasanton, CA 94588, United States of America 
   (e)   350 Sansome Street, Unit 800, San Francisco, CA 94104, United States of America 
   (f)    77 Water Street, Suite 817, New York, NY 10005, United States of America 

The addresses listed above are also the registered offices of the relevant entities.

   8.             EQUITY INVESTMENTS CLASSIFIED AS FVTOCI 
 
 Represent equity securities classified 
  as FVTOCI 
                                                2019        2018 
                                            GBP000's    GBP000's 
----------------------------------------  ----------  ---------- 
 
 At 1 January                                  2,768       2,863 
 Remeasurement to fair value on initial 
  application of IFRS 9                            -       3,744 
 Change in fair value during the year        (1,300)     (3,839) 
 
   At 31 December                              1,468       2,768 
----------------------------------------  ----------  ---------- 
 
 
                                                              % of issued 
Name                             Country of incorporation   share capital  Currency denomination  GBP000's 
------------------------------  -------------------------  --------------  ---------------------  -------- 
 
PDS Biotechnology Corporation                         USA          10.28%                    US$     1,089 
CytoVale, Inc.                                        USA           1.00%                    US$       379 
 
                                                                                                     1,468 
 --------------------------------------------------------  --------------  ---------------------  -------- 
 

The Company's ownership of the enlarged PDS Biotechnology Corporation, now trading on Nasdaq under the ticker PDSB, on a fully diluted basis is 8.15% (2018: 9.12%), which at the year-end listing price of $2.65 values NetScientific's holding in PDS at GBP1,097k (2018: GBP2,380k). It is the Company's intention to hold the shares and to make a decision on its position in due course. The Group's interest in PDS Biotechnology is non-controlling.

The fair value for the prior year end was derived from the listed entity Edge Therapeutics, Inc. and using its share price as a proxy to value PDS. On the 18 March 2019 PDS announced the closing of its merger with Edge Therapeutics, Inc. following the approval of Edge stockholders on 14 March 2019.

CytoVale Inc. remains not quoted on an active market at year end and fair value has been established initially using inputs from other than quoted prices that are observable; i.e. the price of recent investments by third parties during December 2019. CytoVale raised $15.0m all at the same valuation per share, the fundraise was restricted to a small group of sophisticated investors. At the time this was the only observable valuation on which to value CytoVale.

   9.             FINANCIAL ASSETS CLASSIFIED AS FVTPL 
 
  Warrants & Convertible Loans classified                      Restated 
   as FVTPL                                            2019        2018 
                                                   GBP000's    GBP000's 
----------------------------------------------  -----------  ---------- 
 
  Balance at 1 January                                  297         460 
  Change in fair value on initial application 
   of IFRS 9                                              -          51 
  Change in fair value during the year                 (35)       (214) 
----------------------------------------------  -----------  ---------- 
 
    Balance at 31 December                              262         297 
----------------------------------------------  -----------  ---------- 
 

The warrant has been valued using the Black-Scholes Model and a level 3 fair value hierarchy, given the unobservable data for volatility and its fair value. These warrants may be exercised at any time prior to May 2021.

The Epibone convertible loan note is the only financial asset to have a material value individually or collectively the rest have been fully impaired.

Convertible loans FVTPL of GBP253k in the prior year have been moved out of trade and other receivables to financial assets classified as FVTPL. The amount was not material at 1 January 2018 and there is no impact on net assets.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

END

FR MZGZDLVZGGZG

(END) Dow Jones Newswires

April 27, 2020 02:00 ET (06:00 GMT)

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