UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

 

SCHEDULE 14D-9

SOLICITATION/RECOMMENDATION STATEMENT

UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934

 

 

SYNAGEVA BIOPHARMA CORP.

(Name of Subject Company)

 

 

SYNAGEVA BIOPHARMA CORP.

(Name of Person(s) Filing Statement)

 

 

Common Stock, par value $0.001 per share

(Title of Class of Securities)

87159A103

(CUSIP Number of Common Stock)

Sanj K. Patel

President & Chief Executive Officer

Synageva BioPharma Corp.

33 Hayden Avenue

Lexington, Massachusetts 02421

(781) 357-9900

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications on

Behalf of the Person(s) Filing Statement)

 

 

With copies to:

 

Paul M. Kinsella Matthew G. Hurd
Ropes & Gray LLP Krishna Veeraraghavan
Prudential Tower Sullivan & Cromwell LLP
800 Boylston Street 125 Broad Street
Boston, Massachusetts 02199 New York, NY 10004
(617) 951-7000 (212)558-4000

 

 

 

¨   Check the box if the filing relates solely to preliminary communications made before the commencement of a tender offer.

 

 

 


Item 1. Subject Company Information.

 

(a) Name and Address.

The name of the subject company is Synageva BioPharma Corp., a Delaware corporation (the “Company”). The address of the Company’s principal executive offices is 33 Hayden Avenue, Lexington, Massachusetts 02421, and the telephone number of its principal executive offices is (781) 357-9900.

 

(b) Securities.

The title of the class of equity securities to which this Solicitation/Recommendation Statement on Schedule 14D-9 (this “Schedule 14D-9”) relates is the Company’s common stock, par value $0.001 per share (the “Shares” and each, a “Share”). As of May 15, 2015, there were 37,225,329 Shares issued and outstanding.

 

Item 2. Identity and Background of Filing Person.

 

(a) Name and Address.

The name, business address and business telephone number of the Company, which is the person filing this Schedule 14D-9 and the subject company, are set forth in Item 1(a) above.

 

(b) Tender Offer.

This Schedule 14D-9 relates to the exchange offer by Pulsar Merger Sub Inc., a Delaware corporation (“Offeror”) and a direct wholly owned subsidiary of Alexion Pharmaceuticals, Inc., a Delaware corporation (“Alexion”), to acquire all of the outstanding Shares in exchange for each Share validly tendered and not properly withdrawn, consideration in the form of:

 

    $115.00 in cash (the “Cash Consideration”); and

 

    0.6581 shares of Alexion common stock, plus cash in lieu of fractional shares (the “Stock Consideration”);

in each case, without interest, but subject to any required withholding of taxes (such consideration as it may be amended from time to time pursuant to the terms of the Transaction Agreement (as defined below), the “Transaction Consideration”), and upon the terms and subject to the conditions set forth in the Prospectus/Offer to Exchange, dated May 22, 2015 (the “Prospectus/Offer to Exchange”), and in the related Letter of Transmittal (the “Letter of Transmittal” which, together with the Prospectus/Offer to Exchange, and together with any amendments or supplements thereto, constitutes the “Offer”). The Offer is described in a Tender Offer Statement on Schedule TO (as amended or supplemented from time to time, the “Schedule TO”) filed by Alexion and Offeror with the Securities and Exchange Commission (the “SEC”) on May 22, 2015 and in the Prospectus/Offer to Exchange, which is part of a Registration Statement on Form S-4 filed by Alexion with the SEC on May 22, 2015. The Prospectus/Offer to Exchange and the Letter of Transmittal have been filed as Exhibits (a)(1)(A) and (a)(1)(B) hereto, respectively.

The Offer is being made pursuant to the Agreement and Plan of Reorganization, dated as of May 5, 2015, by and among Alexion, Offeror, Galaxy Merger Sub LLC, a Delaware limited liability company and direct wholly owned subsidiary of Alexion (“Merger Sub”) and the Company (the “Transaction Agreement”). The Transaction Agreement has been filed herewith as Exhibit (e)(1) and is incorporated herein by reference. The Transaction Agreement is summarized under the caption “Transaction Agreement” of the Prospectus/Offer to Exchange.

The Transaction Agreement provides that, among other things, subject to the satisfaction or waiver of certain conditions, following completion of the Offer, and in accordance with the General Corporation Law of the State of Delaware (“DGCL”), Offeror will be merged with and into the Company (the “First Merger”), with the Company continuing as the surviving corporation (the “First Surviving Corporation”) as a wholly owned

 

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subsidiary of Alexion. Because the First Merger will be governed by Section 251(h) of the DGCL, no stockholder vote will be required to consummate the First Merger. At the effective time of the First Merger (the “Effective Time”), each outstanding Share (other than (i) Shares owned by Alexion, Offeror or the Company or any direct or indirect wholly owned subsidiary of Alexion or the Company, including all Shares held by the Company as treasury stock, or (ii) Shares that are held by any stockholder who is entitled to demand and properly demands appraisal pursuant to, and who complies in all respects with the provisions of, Section 262 of the DGCL with respect to such Shares) will be converted into the right to receive the Transaction Consideration from Offeror (the “Merger Consideration”).

Alternatively, if any of the conditions to the Offer are not yet satisfied as of any scheduled expiration date of the Offer occurring after July 12, 2015, Alexion may elect to cause the termination of the Offer and seek to instead effect the First Merger through a “long-form” merger governed by Section 251(c) of the DGCL, and accordingly a vote of the Company’s stockholders will be required to consummate the First Merger. If the Offer is terminated and the parties instead propose to effect the transactions through a long-form merger, the Company will convene a meeting of the Company stockholders to seek their approval of the Transaction Agreement.

Regardless of whether the First Merger is completed with or without a stockholder vote, immediately following the First Merger, the First Surviving Corporation will merge with and into Merger Sub, with Merger Sub surviving such second merger (the “Second Merger”, together with the First Merger, the “Mergers”, and Merger Sub thereafter, the “Surviving Company”). As a result of the Second Merger, the Surviving Company will be converted from a corporation into a limited liability company. It is intended that the Offer and the Mergers, taken to together, to qualify as a “reorganization” within the meaning of Section 368(a) of the Internal Revenue Code of 1986, as amended (the “Code”). Please read the discussion under the caption “Material U.S. Federal Income Tax Consequences” in the Prospectus/Offer to Exchange.

Alexion formed Offeror and Merger Sub in connection with the Transaction Agreement, the Offer and the Mergers. The Schedule TO states that the principal executive offices of each of Alexion, Offeror and Merger Sub are located at 352 Knotter Drive, Cheshire, Connecticut 06410.

The Offer and withdrawal rights will expire at 12:00 midnight, New York City time, at the end of June 19, 2015, subject to extension in certain circumstances as required or permitted by the Transaction Agreement, the SEC or applicable law.

The foregoing summary of the Offer is qualified in its entirety by the more detailed description and explanation contained in the Prospectus/Offer to Exchange.

Information relating to the Offer, including this Schedule 14D-9 and related documents, can be found on the SEC’s website, www.sec.gov, or on the Company’s website at www.synageva.com. Alexion and Offeror have filed the Schedule TO and the Prospectus/Offer to Exchange on the SEC’s website.

 

Item 3. Past Contacts, Transactions, Negotiations and Agreements.

Conflicts of Interest

Except as set forth in this Schedule 14D-9 or in the excerpts from the Company’s 2015 Definitive Proxy Statement, dated April 28, 2015 (the “2015 Proxy Statement”), filed as Exhibit (e)(2) to this Schedule 14D-9 (and incorporated by reference into this Item 3), as of the date of this Schedule 14D-9, to the knowledge of the Company, there are no material agreements, arrangements or understandings or actual or potential conflicts of interest between the Company or its affiliates and (i) its executive officers, directors or affiliates, or (ii) Alexion, Offeror or their respective executive officers, directors or affiliates. For further information with respect to these matters, see the 2015 Proxy Statement under the headings: “Beneficial Ownership of Common Stock”; “Executive Compensation”; “Summary Compensation Table”; “2014 Grants of Plan-Based Awards”;

 

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“Outstanding Equity Awards at 2014 Fiscal Year-End”; “Option Exercises and Stock Vested For Fiscal 2014”; “Retirement Benefits”; “Potential Payments Upon Termination or Change of Control”; “Securities Authorized for Issuance Under Equity Compensation Plans”; “Director Compensation For Fiscal 2014”; and “Certain Relationships and Related Party Transactions.”

 

(a) Arrangements with Current Executive Officers, Directors and Affiliates of the Company.

The following is a discussion of all material agreements, arrangements, understandings and any actual or potential conflicts of interest between the Company and its executive officers, directors and affiliates that relate to the Offer and the Mergers.

Interests of Certain Persons

Certain members of management and the Company’s board of directors (the “Company Board”) may be deemed to have certain interests in the Offer and Mergers that are different from or in addition to the interests of the Company’s stockholders generally. The Company Board was aware of these interests and considered that such interests may be different from or in addition to the interests of the Company’s stockholders generally, among other matters, in determining to approve the Offer and the Mergers.

For further information with respect to the arrangements between the Company and its named executive officers, see the information included in Item 8 under the heading “Additional Information — Golden Parachute Compensation,” which is incorporated by reference herein.

Consideration for Common Stock, Stock Options and Restricted Stock Units In Connection with the Offer and Mergers

Consideration for Common Stock

If the directors and executive officers of the Company who own Shares tender their Shares for purchase pursuant to the Offer, they will receive the same consideration for their Shares on the same terms and conditions as the other stockholders of the Company. As agreed by Alexion under the terms of the Transaction Agreement, if the Mergers are consummated, any Shares held of record or beneficially owned by a director or executive officer that are not tendered into the Offer will be converted into the right to receive the Transaction Consideration at the Effective Time.

The approximate value of the cash payments and the number of shares of Alexion common stock that each director and executive officer of the Company would receive in exchange for his or her Shares in the Offer if they were to tender their Shares is set forth in the table below. Each holder of a Share who would otherwise be entitled to receive a fraction of a share of Alexion common stock under the Transaction Agreement in respect of a Share will be paid an amount in cash (without interest) equal to (x) such fractional part of a share of Alexion common stock multiplied by (y) the average of the closing prices per share of Alexion common stock on the Nasdaq Global Select Market, as reported in the New York City edition of The Wall Street Journal (or, if not reported thereby, as reported in another authoritative source) for the ten full trading days ending on the third business day prior to the date on which the Mergers close (the “Parent Trading Price”), rounded down to the nearest one-hundredth of a cent. This information is based on the number of Shares held by the Company’s directors and executive officers as of May 21, 2015, a price per share of Alexion common stock of $161.50 (which is the average closing price of a share of common stock of Alexion on the Nasdaq Global Select Market over the first five business days following May 6, 2015, the date on which the execution of the Transaction Agreement was first publicly announced) and an assumed Parent Trading Price of $161.50, for the calculation of

 

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cash in lieu of fractional shares. The amounts set forth in the table below are as calculated before any taxes that may be due on such amounts are paid.

 

Name of Executive
Officer or Director
   Number
of Shares
Owned
     Cash
Consideration
for Shares
Owned ($)(2)
     Number of
Shares of
Alexion
Common Stock
Received for
Shares Owned
     Total Value of
Shares Owned
($)(3)
 

Felix J. Baker (1)

     11,804,394         1,357,505,422         7,768,471         2,612,129,025   

Robert Bazemore

     —           —           —           —     

Stephen R. Biggar

     102         11,750         67         22,571   

Carsten Boess

     —           —           —           —     

Stephen R. Davis

     —           —           —           —     

Thomas R. Malley

     46,901         5,393,704         30,865         10,378,463   

Sanj K. Patel

     1,031         118,646         678         228,144   

Barry Quart

     —           —           —           —     

Anthony G. Quinn

     5,637         648,370         3,709         1,247,381   

Thomas J. Tisch

     751,995         86,479,572         494,887         166,404,812   

Glen Williams

     468         53,980         307         103,561   

Peter Wirth

     —           —           —           —     

 

(1) Includes 11,648,182 Shares owned by investment funds advised by Baker Bros. Advisors LP, 12,250 Shares received upon the exercise of stock options issued to Dr. Baker and Julian Baker in each of their capacities as directors of the predecessor to the Company and for which, pursuant to the policies of Baker Bros. Advisors LP, they do not have the right to their pecuniary interest of such Shares, and 143,462 Shares owned by FBB Associates. Dr. Baker has shared voting and investment power over such Shares and disclaims beneficial ownership of such Shares except to the extent of his pecuniary interests therein.
(2) Includes cash for fractional shares of Alexion common stock, calculated based on an assumed Parent Trading Price of $161.50 (which is the average closing price of a share of common stock of Alexion on the Nasdaq Global Select Market over the first five business days following May 6, 2015, the date on which the execution of the Transaction Agreement was first publicly announced).
(3) Includes the cash consideration to be received for Shares owned and the aggregate value of the Alexion stock to be exchanged for Shares owned based on a price per share of Alexion common stock of $161.50 (which is the average closing price of a share of common stock of Alexion on the Nasdaq Global Select Market over the first five business days following May 6, 2015, the date on which the execution of the Transaction Agreement was first publicly announced).

Consideration for Stock Options

As agreed by Alexion under the terms of the Transaction Agreement, if the Mergers are consummated, the vesting of all options to acquire Shares (each, a “Stock Option”) outstanding immediately prior to Effective Time, whether held by directors, executive officers or other employees, will accelerate, such that the Stock Options will become fully vested and cancelled, and the holders thereof will be entitled to receive (without interest) an amount in cash and shares of Alexion common stock equal to (i) the Cash Consideration and the Stock Consideration each multiplied by a number of Shares based on the intrinsic spread value of such Stock Option, based on a $230.00 stock price divided by (ii) $230.00, with the cash portion of such amount rounded down to the nearest cent and with the portion of such amount payable in shares of Alexion common stock rounded down to the nearest one thousandth of a share. Each holder of a Stock Option who would otherwise be entitled to receive a fraction of a share of Alexion common stock under the Transaction Agreement in respect of a Stock Option (after aggregating all of the consideration due with respect to all Shares underlying such Stock Option) will be paid an amount in cash (without interest) equal to (x) such fractional part of a share of Alexion common stock multiplied by (y) Parent Trading Price, rounded down to the nearest cent. Any such consideration

 

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will be paid less applicable taxes, which will be deducted first from the cash portion of the consideration payable in respect of the Stock Options. Any Stock Option with a per-Share exercise price that equals or exceeds $230.00 will be cancelled without any consideration therefor.

The approximate value of the cash payments and the number of shares of Alexion common stock that each director and executive officer of the Company will receive in exchange for his or her Stock Options (assuming that each such director and executive officer does not otherwise exercise any outstanding and vested Stock Options prior to the Effective Time) is set forth in the table below. This information is based on the number of Stock Options held by the Company’s directors and executive officers as of May 21, 2015 and a price per share of Alexion common stock of $161.50 (which is the average closing price of a share of common stock of Alexion on the Nasdaq Global Select Market over the first five business days following May 6, 2015, the date on which the execution of the Transaction Agreement was first publicly announced) and an assumed Parent Trading Price of $161.50, for the calculation of cash in lieu of fractional shares. The amounts set forth in the table below are as calculated before any taxes that may be due on such amounts are paid.

 

Name of Executive
Officer or Director
  Number
of Shares
Subject
to Vested
Stock
Option
    Cash
Consideration
for Vested
Stock
Options ($)(1)
    Number
of Shares
of Alexion
Common
Stock
Received
for Vested
Stock
Options
    Number of
Shares
Subject to
Unvested
Stock
Options
    Cash
Consideration
for Unvested
Stock
Options ($)(1)
    Number of
Shares of
Alexion
Common Stock
Received for
Vested Stock
Options
    Total
Value of Stock
Options ($) (2)
 

Felix J. Baker

    52,622        5,107,991        29,231        628        46,990        269        9,919,281   

Robert Bazemore

    —          —          —          50,000        4,172,250        23,876        8,028,297   

Stephen R. Biggar

    36,872        3,487,722        19,959        628        46,990        269        6,801,539   

Carsten Boess

    37,950        3,821,891        21,871        80,209        6,835,240        39,115        20,506,586   

Stephen R. Davis

    52,872        5,179,247        29,639        628        46,990        269        10,056,393   

Thomas R. Malley

    44,298        4,338,119        24,825        628        46,990        269        8,437,884   

Sanj K. Patel

    298,049        29,602,837        169,405        256,515        22,172,050        126,882        99,625,898   

Barry Quart

    29,248        2,772,324        15,865        628        46,990        269        5,424,959   

Anthony G. Quinn

    107,832        11,330,632        64,841        89,839        7,699,049        44,059        36,617,156   

Thomas J. Tisch

    28,538        2,566,026        14,684        1,462        125,912        721        5,179,860   

Glen Williams

    1        95        1        80,001        6,564,500        37,566        12,631,687   

Peter Wirth

    28,538        2,566,026        14,684        1,462        125,912        721        5,179,860   

 

(1) Includes cash for fractional shares of Alexion common stock, calculated based on an assumed Parent Trading Price of $161.50 (which is the average closing price of a share of common stock of Alexion on the Nasdaq Global Select Market over the first five business days following May 6, 2015, the date on which the execution of the Transaction Agreement was first publicly announced).
(2) Includes the cash consideration to be received for Stock Options and the aggregate value of the Alexion common stock to be received for Stock Options based on a price per share of Alexion common stock of $161.50 (which is the average closing price of a share of common stock of Alexion on the Nasdaq Global Select Market over the first five business days following May 6, 2015, the date on which the execution of the Transaction Agreement was first publicly announced).

Consideration for Restricted Stock Units

As agreed by Alexion under the terms of the Transaction Agreement, if the Mergers are consummated under the terms of the Transaction Agreement, the vesting of all restricted stock units (“RSUs”) outstanding immediately prior to the Effective Time other than the “Rolled 2015 RSUs Award” (as defined below), whether held by directors, executive officers or other employees will be accelerated, such that all such RSUs will become fully vested and be cancelled, and the holders thereof will be entitled to receive (without interest) an amount in cash and a number of shares of Alexion common stock equal to the Transaction Consideration in respect of each

 

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Share subject to such RSUs outstanding immediately prior to the Effective Time. Any such consideration will be paid less applicable taxes, which will be deducted first from the cash portion of the consideration payable in respect of the RSUs.

With respect to one half of each RSU award that is granted after the signing of the Transaction Agreement (such portion of the award, the “Rolled 2015 RSUs Award”) that is outstanding immediately prior to the Effective Time, such Rolled 2015 RSUs Award will be converted into a restricted stock unit award in respect of Alexion common stock, with the number of shares of Alexion common stock underlying such converted award determined by multiplying (x) the number of Shares subject to such Rolled 2015 RSUs Award by (y) the sum of (1) the Stock Consideration and (2) the quotient of the Cash Consideration, divided by the Parent Trading Price, with each converted award to continue to be subject to the same terms and conditions as were applicable to the related Rolled 2015 RSU Award immediately prior to the Effective Time (including accelerated vesting upon a termination without “cause” or resignation for “good reason” within two years following the Effective Time). The other half of each RSU award that is granted after the signing of the Transaction Agreement will be treated as provided in the immediately preceding paragraph.

As of the date of this Schedule 14D-9, no RSU awards have been granted after the signing of the Transaction Agreement. However, as agreed by Alexion under the terms of the Transaction Agreement, during the period between the signing of the Transaction Agreement and the Effective Date, the Company may grant RSU awards covering an aggregate number of Shares not to exceed 395,652 Shares (which was determined by dividing $91,000,000 by $230,000). As agreed by Alexion and the Company, the allocation of such awards is to be reasonably consistent with the Company’s past practice with respect to its normal annual grant cycle, and the Company must provide to Alexion, a reasonable time in advance of the date that the Company proposes to grant such awards in respect of its normal annual grant cycle, a schedule of the awards that are proposed to be made for each level of employee. Except as otherwise provided in this section, such RSU awards will vest, subject to the applicable employee’s continued service, (x) 25% on the first anniversary of the applicable grant date and (y) 12.5% per six months thereafter (such that the award will be 100% vested on the fourth anniversary of the grant date). The Company’s executive officers are expected to receive grants under this pool, but no grants have been made as of the date of this Schedule 14D-9. Once made, any such grants will be treated as provided in the two immediately preceding paragraphs.

As of May 21, 2015, Mr. Bazemore was the only executive officer who held any RSUs. None of the Company’s other executive officers or non-employee directors held any RSUs as of such date. Based on the 30,000 RSUs held by Mr. Bazemore as of May 21, 2015, and assuming that the Effective Time occurs on May 21, 2015, he will receive $3,450,000 in cash consideration and 19,743 shares of Alexion common stock, resulting in an aggregate value of $6,638,534 (based on a price per share of Alexion common stock of $161.50, which is the average closing price of a share of common stock of Alexion on the Nasdaq Global Select Market over the first five business days following May 6, 2015, the date on which the execution of the Transaction Agreement was first publicly announced, and an assumed Parent Trading Price of $161.50 for the calculation of cash in lieu of fractional shares). The amounts in the preceding sentence are calculated before any taxes that may be due on such amounts are paid.

 

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Summary of Equity-Related Payments Resulting from the Offer and the Mergers

The following table sets forth the approximate amount of payments and the number of shares of Alexion common stock that each director and executive officer of the Company is entitled to receive in connection with the consummation of the Offer and Mergers as a result of the Company equity interests held by each director and executive officer as of May 21, 2015. The table does not include any payments the executive officers may be entitled to if the employment of executive officers is terminated in connection with the Offer. Such payments are detailed below in the section entitled “Employment Agreements and Severance Payments.”

 

Name of Executive Officer or Director    Value of
Shares Owned
($)
     Value of Stock
Options ($)
     Value of RSUs
($)(2)
    

Total

Value of Equity
($)

 

Felix J. Baker (1)

     2,612,129,025         9,919,281         —           2,622,048,306   

Robert Bazemore

     —           8,028,297         6,638,534         14,666,831   

Stephen R.Biggar

     22,571         6,801,539         —           6,824,110   

Carsten Boess

     —           20,506,586         —           20,506,586   

Stephen R. Davis

     —           10,056,393         —           10,056,393   

Thomas R. Malley

     10,378,463         8,437,884         —           18,816,347   

Sanj K. Patel

     228,144         99,625,898         —           99,625,898   

Barry Quart

     —           5,424,959         —           5,424,959   

Anthony G. Quinn

     1,247,381         36,617,156         —           37,864,536   

Thomas J. Tisch

     166,404,812         5,179,860         —           171,584,672   

Glen Williams

     103,561         12,631,678         —           12,735,239   

Peter Wirth

     —           5,179,860         —           5,179,860   

 

(1) Includes 11,648,182 Shares owned by investment funds advised by Baker Bros. Advisors LP, 12,250 Shares received upon the exercise of stock options issued to Dr. Baker and Julian Baker in each of their capacities as directors of the predecessor to the Company and for which, pursuant to the policies of Baker Bros. Advisors LP, they do not have the right to their pecuniary interest of such Shares, and 143,462 Shares owned by FBB Associates. Dr. Baker has shared voting and investment power over such Shares and disclaims beneficial ownership of such Shares except to the extent of his pecuniary interests therein.
(2) As discussed under “—Consideration for Restricted Stock Units” above, the Company’s executive officers are expected to receive grants of RSUs between the signing of the Transaction Agreement and the Effective Date. However, as of the date of this Schedule 14D-9, no such grants have been made. Accordingly, they are not reflected in this table.

Treatment of the Company’s 2014 Employee Stock Purchase Plan

Each outstanding offering period under the Company’s 2014 Employee Stock Purchase Plan (the “ESPP”) that is in progress as of the date of the execution of the Transaction Agreement will terminate, and all accumulated contributions to purchase Company common stock under the ESPP will be used to purchase Company common stock, on the earlier of (x) the scheduled purchase date for such offering period, and (y) the date that is seven business days prior to the acceptance time of the Offer or, if the Offer has been terminated, the Effective Time. Only current participants in the ESPP may continue to participate in the ESPP and no participant may increase payroll deductions from those in effect at the time the Transaction Agreement was executed. The Company will suspend the commencement of any future offering periods under the ESPP unless and until the Transaction Agreement is terminated, and the ESPP will terminate prior to the time Offeror accepts Shares for payment in the Offer (with any participant payroll deductions not applied to the purchase of Company common stock under the ESPP returned to the applicable participant). The Company currently expects that the final offering period under the ESPP will be the currently-outstanding offering period, which is expected to end on June 30, 2015.

As of May 5, 2015, assuming that the acceptance time of the Offer or, if the Offer is terminated, the Effective Time has not occurred prior to June 30, 2015 and assuming that the executive officers do not withdraw from the

 

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current offering period and a purchase price of $78.87 (which is equal to 85% of the fair market value of a Share at the beginning of the applicable offering period), approximately 54 Shares would be purchased by Mr. Williams and 41 Shares would be purchased by Dr. Quinn at the end of the current offering period on June 30, 2015. None of the Company’s other executive officers or non-employee directors currently participate in the ESPP.

Employment Agreements and Severance Payments

The Company previously entered into employment agreements with each of Mr. Patel, Mr. Boess, Mr. Bazemore, Dr. Quinn and Mr. Williams.

Under the employment agreement with Mr. Patel, if the Company terminates Mr. Patel’s employment without “cause” or he resigns for “good reason” during the 12 months following a change of control, which includes the transactions contemplated by the Transaction Agreement, Mr. Patel will be entitled to the following severance: (i) a lump sum equal to 24 months of his base salary plus two times his target annual cash bonus; (ii) a pro-rata share of his target annual cash bonus for the year in which the termination occurs; and (iii) a one-time bonus of twenty-five thousand dollars ($25,000).

If the Company terminates the employment of Mr. Bazemore, Mr. Boess, Dr. Quinn or Mr. Williams without “cause” during the 12 months following a change of control, which includes the transactions contemplated by the Transaction Agreement, the executive will receive (i) cash severance payable in a lump sum equal to 12 months of his base salary; (ii) a lump sum payment equal to the target annual cash bonus for the year in which the termination occurs; and (iii) a one-time bonus of sixteen thousand five hundred dollars ($16,500).

The employment agreements also provide for non-competition and non-solicitation covenants for 18 months following a termination of employment for Mr. Patel and for 24 months following a termination of employment for the other executive officers. The executives are subject to a Section 280G “net better cutback” and are not entitled to a Section 280G gross-up. The executive officers’ stock option award agreements provide that any “golden parachute” payments subject to the excise tax imposed by Section 4999 of the Code, as amended, will be reduced to the maximum amount that does not trigger the “golden parachute” excise tax unless the executive officer would be better off (on an after-tax basis) receiving all payments and benefits due and paying all applicable excise and income taxes. Accordingly, certain payments and/or benefits contingent on the Mergers that may be made to any such executive officer may be reduced.

Definitions of Cause. Under the employment agreements, “cause” means: (i) gross negligence or willful misconduct in the performance of the executive’s duties to the Company, where such gross negligence or willful misconduct has resulted in material damage to the Company or any of its affiliates or successors; (ii) commission of any act of fraud, embezzlement or professional dishonesty with respect to the Company or any of its affiliates; (iii) commission of a felony or crime involving moral turpitude; (iv) material breach of any provision of the executive’s employment agreement or any other written agreement between such executive and the Company; or (v) failure to comply with lawful directives of the Company Board, in the case of Mr. Patel, or of the CEO, in the case of the other executives, which has caused damage to the Company or any of its affiliates or successors.

Definition of Good Reason. Under Mr. Patel’s employment agreement, Mr. Patel would be entitled to terminate his employment for “good reason” if any of the following events occur without his written consent: (i) the assignment to him of duties materially inconsistent with his title, position, status, reporting relationships, authority, duties or responsibilities; (ii) any action by the Company which results in a diminution in his title, position, status, reporting relationships, authority, duties or responsibilities, other than insubstantial or inadvertent actions not taken in bad faith which are remedied by the Company promptly after receipt of notice thereof given by Mr. Patel; (iii) a requirement that he relocate his primary reporting location to a location more than 50 miles from the location of the Company’s offices in Lexington, Massachusetts; (iv) any failure by the Company to comply with certain provisions of his employment agreement, other than insubstantial or inadvertent failures not in bad faith which are remedied by the Company promptly after receipt of notice thereof given by Mr. Patel; (v) a material diminution in the budget over which he has responsibility; or (vi) a breach by the Company of any written agreement between the Company and Mr. Patel.

 

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Indemnification of Executive Officers and Directors

The Transaction Agreement provides that all rights to indemnification and exculpation from liabilities for acts or omissions occurring at or prior to the Effective Time and rights to advancement of expenses relating thereto in favor of each present and former director or officer of the Company, when acting in their capacity as such (collectively, the “Company Indemnified Parties”), existing on the date of the Transaction Agreement or as at such time provided in the Company’s certificate of incorporation or bylaws or any indemnification agreements between the Company and such Company Indemnified Party, will survive and continue in full force and effect for a period of six years after the Effective Time.

The Transaction Agreement also provides that from and after the Effective Time, the First Surviving Corporation and the Surviving Company will indemnify and hold harmless, to the fullest extent permitted by applicable law, each Company Indemnified Party against any costs or expenses (including reasonable attorneys’ fees), judgments, fines, losses, claims, damages or liabilities incurred in connection with any claim, action, suit, proceeding or investigation, whether civil, criminal, administrative or investigative, arising out of or related to such individual’s service as a director or officer of the Company prior to or at the Effective Time. The First Surviving Corporation and the Surviving Company will also advance funds in respect of each Company Indemnified Party as incurred and to the fullest extent permitted by applicable law; provided that such Company Indemnified Party undertakes to repay such advances if it is finally determined that such person was not entitled to indemnification.

Prior to the Effective Time, the Company will obtain and fully pay the premium for directors and officers liability insurance and fiduciary liability insurance with a claims reporting or discovery period of at least six years after the Effective Time, with terms and conditions at least as favorable as the Company’s existing policies. If the Company fails to obtain such “tail” policy, then for six years after the Effective Time, the Surviving Company must either maintain in effect the insurance and indemnification policy of the Company in effect as of the date of the Transaction Agreement or obtain an alternative insurance and indemnification policy, in each case with terms and conditions at least as favorable as the Company’s existing policies, provided that the Surviving Company will not be required to pay annual premiums in excess of 300% of the premiums paid by the Company as of the date of the Transaction Agreement.

The foregoing summary of the indemnification of executive officers and directors and directors’ and officers’ insurance does not purport to be complete and is qualified in its entirety by reference to the Transaction Agreement, which has been filed as Exhibit (e)(1) hereto and is incorporated herein by reference.

Executive Officer and Director Arrangements Following the Mergers

As of the date of this Schedule 14D-9, none of the Company’s current executive officers have entered into any agreement with Alexion, the Company or their respective affiliates regarding employment with Alexion, the Company or their respective affiliates after the First Effective Time, although it is possible that Alexion, the Company or their respective affiliates may enter into employment or other arrangements with the Company’s executive officers in the future.

In connection with the Mergers, Alexion will appoint Felix J. Baker to Alexion’s board of directors. Dr. Baker will receive compensation on the same basis as other non-employee directors of Alexion.

Effect of the Transaction Agreement on Employee Benefits

The Transaction Agreement provides that for the period from the Effective Time until the second anniversary of the Effective Time, Alexion will provide, or will cause the Surviving Company to provide, to each employee of the Company or its subsidiaries who continues to be employed by Alexion, the Surviving Company or any of their respective subsidiaries following the Effective Time (“Company Employees”) with (i) annual target cash compensation (in the form of base salary and annual target bonus opportunity) which is no less than

 

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that provided to such Company Employee immediately prior to the Effective Time, (ii) employee benefits that are no less favorable in the aggregate than employee benefits provided to similarly situated employees of Alexion and its subsidiaries, (iii) in respect of each of fiscal year 2015 and fiscal year 2016, an equity-based incentive compensation opportunity that is no less favorable than that provided to similarly situated employees of Alexion and its subsidiaries and (iv) severance benefits under a broad-based severance policy or plan that are no less favorable than the severance benefits under a broad-based severance policy or plan provided to similarly situated employees of Alexion and its subsidiaries; it being understood that the Company Employees may commence participation in Alexion’s compensation and benefit plans on different dates following the Effective Time with respect to different compensation and benefit plans.

Alexion will, or will cause the Surviving Company to, cause any employee benefit plans sponsored or maintained by Alexion, the Surviving Company or their subsidiaries in which the Company Employees are eligible to participate following the date upon which the Mergers are consummated (collectively, the “Post-Closing Plans”) to recognize the service of each Company Employee with the Company and its subsidiaries and their respective predecessors prior to the Effective Time for purposes of eligibility, vesting and benefit accrual (including, but not limited to, vacation and other paid time off credit) under such Post-Closing Plans, to the same extent such service was recognized immediately prior to the Effective Time under a comparable Company benefit plan in which such Company Employee was eligible to participate immediately prior to the Effective Time; provided that such recognition of service will not (i) apply for purposes of any defined benefit retirement plan or plan that provides retiree welfare benefits, (ii) operate to duplicate any benefits of a Company Employee with respect to the same period of service, (iii) apply for purposes of any plan, program or arrangement (x) under which similarly situated employees of Alexion and its subsidiaries do not receive credit for prior service or (y) that is grandfathered or frozen, either with respect to level of benefits or participation. With respect to any Post-Closing Plan that provides medical, dental, pharmaceutical or vision insurance benefits, for the plan year in which such Company Employee is first eligible to participate, Alexion will use commercially reasonable efforts to cause any pre-existing condition limitations or eligibility waiting periods or actively-at-work requirements under such plan to be waived with respect to such Company Employee to the extent such limitation would have been waived or satisfied under the comparable Company benefit plan in which such Company Employee participated immediately prior to the Effective Time, and credit each Company Employee for an amount equal to any medical, dental, pharmaceutical or vision expenses incurred by such Company Employee in the year that includes the date on which the Mergers close (or, if later, the year in which such Company Employee is first eligible to participate in such Post-Closing Plan, if applicable) for purposes of any applicable deductible, coinsurance and annual out-of-pocket expense requirements under any such Post-Closing Plan to the extent such expenses would have been credited under the comparable Company benefit plan in which such Company Employee participated immediately prior to the Effective Time.

If the Effective Time occurs during calendar year 2015, each participant in a Company annual cash incentive compensation plan who was a participant as of immediately prior to May 5, 2015 and who remains employed with Alexion or its subsidiaries (including the Surviving Company) through December 31, 2015 and receives at least a “meets expectations” or equivalent performance rating under the applicable incentive plan, will receive, at the time that bonuses are normally paid pursuant to the applicable incentive plan, an annual cash incentive payment in respect of the 2015 fiscal year under the incentive plan, equal to the higher of (i) the cash bonus payable at the target level of performance (at 100% funding) under the applicable incentive plan (the “Target 2015 Bonus”) and (ii) the actual level of performance achieved with respect to the 2015 fiscal year, as determined in accordance with the terms of the applicable incentive plan; provided that if a participant’s employment is terminated without cause on or following the Effective Time and on or prior to December 31, 2015, such participant will receive a pro-rated portion of his or her Target 2015 Bonus, with such proration determined as required under the terms of a given Company benefit plan or otherwise in accordance with Alexion’s severance plan.

 

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The Company will terminate its 401(k) plan(s) as of the day immediately preceding the Effective Time if Alexion provides timely written notice requesting such termination in accordance with the Transaction Agreement.

Section 16 Matters

Pursuant to the Transaction Agreement, Alexion and the Company will take all steps as may be required to cause any dispositions of all Shares (including derivative securities with respect to Shares) or acquisitions of shares of Alexion common stock (including derivative securities with respect to Alexion common stock) resulting from the Mergers and Offer by each individual who is subject to the reporting requirements of Section 16(a) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) with respect to the Company or will become subject to such reporting requirements with respect to Alexion, to be exempt under Rule 16b-3 promulgated under the Exchange Act.

Rule 14d-10(d) Matters

Pursuant to the Transaction Agreement, the compensation committee of the Company Board, at a meeting to be held prior to the time Offeror accepts the Shares for payment, will duly adopt resolutions approving as an “employment compensation, severance or other employee benefit arrangement” within the meaning of Rule 14d-10(d)(1) under the Exchange Act (i) each employment compensation, severance and other employee benefit plans of the Company presented to the compensation committee, (ii) the treatment of the Company stock awards in accordance with the terms set forth in the Transaction Agreement, and (iii) the applicable terms of the Transaction Agreement. In addition, the compensation committee of the Company Board will take all other actions necessary to satisfy the requirements of the non-exclusive safe harbor under Rule 14d-10(d)(2) under the Exchange Act with respect to the foregoing arrangements.

 

(b) Arrangements with Offeror and Alexion.

Transaction Agreement

The summary of the Transaction Agreement contained in the section of the Prospectus/Offer to Exchange entitled “The Transaction Agreement” filed as Exhibit (a)(1)(A) hereto and the description of the conditions of the Offer contained in the section of the Prospectus/Offer to Exchange entitled “The Transaction Agreement—Conditions to the Transaction—Conditions to the Offer” are incorporated herein by reference. Such summary and description are qualified in their entirety by reference to the Transaction Agreement, which is filed as Exhibit (e)(1) hereto and is incorporated herein by reference.

The Transaction Agreement governs the contractual rights between the Company, Alexion, Offeror and Merger Sub in relation to the Offer and the Mergers. The Transaction Agreement has been filed as an exhibit to this Schedule 14D-9 to provide you with information regarding the terms of the Transaction Agreement and is not intended to modify or supplement any factual disclosures about the Company or Alexion in the Company’s or Alexion’s public reports filed with the SEC. In particular, the Transaction Agreement and this summary of terms are not intended to be, and should not be relied upon as, disclosures regarding any facts or circumstances relating to the Company or Alexion. The representations and warranties have been negotiated with the principal purpose of establishing the circumstances in which Offeror may have the right not to consummate the Offer, or a party may have the right to terminate the Transaction Agreement, if the representations and warranties of the other party prove to be untrue due to a change in circumstance or otherwise, and allocate risk between the parties, rather than establish matters as facts. The representations and warranties may also be subject to a contractual standard of materiality different from those generally applicable to stockholders.

Voting and Support Agreements

Simultaneously with the execution and delivery of the Transaction Agreement, Thomas J. Tisch, a director of the Company, and investment funds advised by an adviser affiliated with Felix J. Baker, a director of the

 

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Company, entered into voting and support agreements (the “Voting and Support Agreements”) with Alexion and Offeror, pursuant to which, among other things and subject to the terms and conditions therein, such stockholders agreed to vote all Shares beneficially owned by such stockholders, representing approximately 33.36% of the outstanding Shares of the Company, in favor of the adoption of the Transaction Agreement and the approval of the transactions contemplated by the Transaction Agreement, including the First Merger, and any other matter necessary to consummate such transactions, and not to vote in favor of, or tender their Shares into, any competing offer or takeover proposal. Each Voting and Support Agreement terminates automatically, among other things, upon the termination of the Transaction Agreement.

Confidentiality Agreement

On March 9, 2015, the Company and Alexion entered into a confidentiality agreement, pursuant to which the Alexion agreed to keep confidential certain information furnished to Alexion concerning the Company’s business in connection with the evaluation of a possible transaction between Alexion and the Company and to use such information solely for the purpose of evaluating, negotiating and, if applicable, consummating the transaction. On April 22, 2015, the Company and Alexion entered into a confidentiality agreement, pursuant to which the Company agreed to keep confidential certain information furnished to the Company concerning Alexion’s business in connection with the evaluation of a possible transaction between Alexion and the Company and to use such information solely for the purpose of evaluating, negotiating and, if applicable, consummating the transaction. On April 27, 2015, the Company and Alexion entered into an intellectual property common interest agreement in which the Company and Alexion reaffirmed a mutual common legal interest with respect to a possible transaction and the Company and Alexion agreed to keep confidential certain privileged information furnished to Alexion, in connection with the evaluation or pursuit of a possible transaction between Alexion and the Company.

 

Item 4. The Solicitation or Recommendation.

 

(a) Recommendation of the Company Board.

After consideration, including review of the terms and conditions of the Offer in consultation with the Company’s management, as well as the Company’s financial and legal advisors, the Company Board, by unanimous vote at a meeting on May 5, 2015, (a) determined that the Offer and the Mergers are fair to, and in the best interests of, the Company and its stockholders, (b) approved, declared advisable and adopted the Transaction Agreement and (c) resolved to recommend that the Company’s stockholders accept the Offer and tender their Shares in the Offer.

Accordingly, for the reasons described in more detail below, the Company Board unanimously recommends that the Company’s stockholders accept the Offer and tender their Shares to Offeror pursuant to the Offer.

 

(b) Background and Reasons for the Company Board’s Recommendation.

Background of the Offer

The Company Board, with the assistance of the Company’s senior management, has regularly reviewed the Company’s research and development activities relating to its product candidates, the potential for commercializing its product candidates, and the strategic alternatives available to the Company to maximize stockholder value. As part of this review, the Company Board has periodically considered whether the continued execution of the Compnay’s business strategy as a standalone company, or a possible license or sale of assets to, or a business combination with, a third party would provide the best avenue to enhance stockholder value. In January 2015, the Company raised approximately $308.7 million in a public offering of Shares to help fund the Company’s expected cash needs as an independent entity. Investment funds advised by an adviser affiliated with Dr. Baker purchased 1,000,000 Shares in the January 2015 public offering.

 

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Alexion has advised the Company that the Board of Directors of Alexion (the “Alexion Board”), with the assistance of Alexion’s senior management, has regularly reviewed opportunities for expanding Alexion’s metabolic rare disease franchise and pipeline, including by acquisition of development stage companies. Alexion has advised the Company that for the reasons described in the section of the Prospectus/Offer to Exchange entitled “—Alexion’s Reasons for the Transactions”, during these reviews Alexion had identified the Company as a potential acquisition opportunity. Alexion has advised the Company that on February 16, 2015, the Alexion Board met telephonically, together with members of Alexion’s senior management and representatives of Lazard, Alexion’s financial advisor, and Wachtell, Lipton, Rosen & Katz, Alexion’s external mergers and acquisitions counsel (“Wachtell Lipton”), to discuss the possibility of making an acquisition proposal for the Company. Alexion has advised the Company that, as a result of this meeting, the Alexion Board authorized Alexion’s senior management to communicate to the Company Alexion’s interest in acquiring the Company for $175 per share (“Alexion’s $175 Proposal”). Alexion has advised the Company that, in addition to this meeting, the Alexion Board met, telephonically or in person, together with members of Alexion’s senior management and representatives of its financial and legal advisors, in advance of each subsequent proposal made to the Company and in advance of final approval of the Transaction Agreement on May 5, 2015, to discuss the status of the transaction, receive presentations from management and the external advisors, and to provide guidance to Alexion’s senior management, including Dr. Leonard Bell and Mr. David Hallal, and during the negotiation of the Transaction Agreement, to Alexion’s legal and financial advisors. At the time, Dr. Bell was Alexion’s Chief Executive Officer and was and continues to serve as Chairman of the Alexion Board. Mr. Hallal, who at the time was Alexion’s Chief Operating Officer and Chief Executive Officer-elect, became Alexion’s Chief Executive Officer on April 1, 2015.

On February 18, 2015, Dr. Bell telephoned Dr. Felix Baker, Chairman of the Company Board, to communicate Alexion’s $175 Proposal, which represented a premium of approximately 77.0% to the Company’s closing price on February 17, 2015, a premium of approximately 61.7% to the Company’s volume-weighted average closing price for the 30 days ended February 17, 2015 and a premium of approximately 44.7% to the Company’s all-time high closing price. Later on February 18, 2015, Dr. Bell telephoned Mr. Sanj K. Patel, the Company’s President and Chief Executive Officer, to discuss Alexion’s $175 Proposal. Dr. Baker and Mr. Patel thereafter contacted the Company’s external legal and financial advisors regarding Alexion’s $175 Proposal. Following the February 18, 2015 calls with Dr. Baker and Mr. Patel, Dr. Bell sent Dr. Baker a letter dated that same day confirming Alexion’s $175 Proposal, which Dr. Baker distributed to the members of the Company Board. In the letter, Alexion invited a member of the Company Board to serve on the Alexion Board following completion of the transaction between the parties.

On February 21, 2015, the Company Board held a meeting to discuss Alexion’s $175 Proposal. Representatives of Sullivan & Cromwell LLP, the Company’s external mergers and acquisitions counsel (“Sullivan & Cromwell”), representatives of Ropes & Gray LLP, the Company’s external corporate counsel (“Ropes & Gray”), and representatives of Goldman, Sachs & Co., the Company’s financial advisor (“Goldman Sachs”) attended the meeting. In engaging Ropes & Gray as one of its external legal advisors, senior management and the Company Board were aware of Ropes & Gray’s representation of Alexion in various unrelated matters. In addition, the Company Board and senior management were aware that Goldman Sachs had previously provided financial services or underwriting services to Alexion, and Goldman Sachs advised the Company Board that during the two year period ended February 18, 2015, the Investment Banking Division of Goldman Sachs had not received any compensation for financial services or underwriting services provided to Alexion. Representatives of Sullivan & Cromwell and Ropes & Gray reviewed with the Company Board their fiduciary duties. The members of the Company Board discussed Alexion’s $175 Proposal among themselves and with representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray, and outlined the information and advice that they wished to receive from the Company’s senior management and the Company’s external advisors.

On March 2, 2015, the Company Board held another meeting to discuss Alexion’s $175 Proposal. Representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray attended the meeting. The Company’s senior management reviewed certain financial projections concerning the Company’s product candidates and described various aspects of the Company’s research, development and commercialization plans.

 

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Representatives of Goldman Sachs reviewed certain indicative financial analyses for the Company and provided an analysis of Alexion’s $175 Proposal in relation to these analyses. A representative of Sullivan & Cromwell described the directors’ fiduciary duties under various scenarios. In addition, the members of the Company Board, while not making a decision on whether to do so, also discussed whether the Company should solicit the interest of other potentially interested counterparties for a potential transaction with the Company. The directors discussed the risks attendant to such potential solicitations and to engaging in a transaction with Alexion or another party at this time, including the potential disruption at a critical juncture to the Company’s business and the regulatory and launch process for its lead product candidate and the diversion of senior management time and attention. Following discussions, it was the consensus of the Company Board that Dr. Baker should communicate to Dr. Bell that the proposed price contained in Alexion’s $175 Proposal did not appear compelling in light of what they believed the Company’s standalone value to be, and that, accordingly, the Company was not interested in discussing a potential transaction with Alexion on the terms outlined in Alexion’s $175 Proposal.

On March 5, 2015, Dr. Baker telephoned Dr. Bell to inform him that the Company was not interested in discussing a potential transaction with Alexion on the terms outlined in Alexion’s $175 Proposal. Dr. Bell informed Dr. Baker that Alexion could potentially improve the terms of Alexion’s $175 Proposal if it were provided with certain nonpublic information about the Company and its product candidates that would assist Alexion in assessing its valuation of the Company.

On March 5, 2015, representatives of Sullivan & Cromwell provided to representatives of Wachtell Lipton a draft confidentiality agreement incorporating a two-year standstill provision pursuant to which Alexion would be prohibited from taking certain actions with respect to the Company for such period. From that date through March 9, 2015, representatives of Sullivan & Cromwell and Wachtell Lipton negotiated the terms of the confidentiality agreement, which was entered into by the Company and Alexion on March 9, 2015.

On March 10, 2015, Mr. Patel and other members of the Company’s senior management met with Dr. Bell and Mr. Hallal. At this meeting the Company provided to Alexion information concerning the Company’s product candidates.

On March 17, 2015, Dr. Bell telephoned Dr. Baker to communicate Alexion’s interest in acquiring the Company for $195 per share in an unspecified mix of cash and Alexion common stock (“Alexion’s $195 Proposal”), which represented a premium of approximately 97.2% to the Company’s closing price on February 17, 2015 which was the day prior to the date Alexion provided Alexion’s $175 Proposal, a premium of approximately 80.2% to the Company’s volume-weighted average closing price for the 30 days prior to the date Alexion provided Alexion’s $175 Proposal and a premium of approximately 61.3% to the Company’s all-time high closing price. Dr. Bell subsequently sent Dr. Baker a letter confirming Alexion’s $195 Proposal, which Dr. Baker distributed to the members of the Company Board.

On March 18, 2015, the Company Board held a meeting to discuss Alexion’s $195 Proposal. Representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray attended the meeting. The members of the Company Board discussed Alexion’s $195 Proposal among themselves and with representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. The Company Board also discussed the risks of engaging in a potential transaction of this type at this time, including the fact that the Company was in a critical juncture in the regulatory and launch process with respect to its lead product candidate and that senior management would be required to divert their attention from that process in order to engage in pursuing a transaction with Alexion. The Company Board also discussed the Company’s standalone prospects and discussed that they were confident in the ability of senior management to continue to operate the Company as an independent company. Following the discussion, it was the consensus of the Company Board that Dr. Baker should communicate to Dr. Bell that the proposed price contained in Alexion’s $195 Proposal did not appear compelling in light of what they believed the Company’s standalone value to be and that, accordingly, the Company was not interested in discussing a potential transaction with Alexion on the terms outlined in Alexion’s $195 Proposal. After the conclusion of the meeting Dr. Baker so informed Dr. Bell. Dr. Bell undertook to discuss the matter again with the Alexion Board.

 

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On March 24, 2015, Dr. Bell telephoned Dr. Baker to communicate Alexion’s interest in acquiring the Company for $212 per share in an unspecified mix of cash and Alexion common stock (“Alexion’s $212 Proposal”), which represented a premium of approximately 114.4% to the Company’s closing price on February 17, 2015, which was the day prior to the date Alexion provided Alexion’s $175 Proposal, a premium of approximately 95.9% to the Company’s volume-weighted average closing price for the 30 days prior to the date Alexion provided Alexion’s $175 Proposal and a premium of approximately 75.3% to the Company’s all-time high closing price. During the conversation, Dr. Bell stated that in order for Alexion to improve its proposal further, Alexion would need to receive and be satisfied with additional information concerning the Company. Dr. Bell subsequently sent Dr. Baker a letter confirming Alexion’s $212 Proposal, which Dr. Baker distributed to the members of the Company Board.

On March 25, 2015, the Company Board held a meeting to discuss Alexion’s $212 Proposal. Representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray attended the meeting. The members of the Company Board discussed Alexion’s $212 Proposal among themselves and with representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. Following the discussion, it was the consensus of the Company Board that Dr. Baker should communicate to Dr. Bell that the proposed price contained in Alexion’s $212 Proposal did not appear compelling in light of what they believed the Company’s standalone value to be and that, accordingly, the Company was not interested in engaging in a potential transaction with Alexion on the terms outlined in Alexion’s $212 Proposal. While the Company Board considered the risks of permitting Alexion to have access to additional information concerning the Company and the diversion of senior management’s time and attention in providing such information, it determined to authorize the Company’s senior management to provide certain limited information concerning the Company to Alexion so that Alexion could determine whether it could improve its offer. On March 26, 2015, Dr. Baker so informed Dr. Bell.

On March 30, 2015, the Company made available to Alexion an online datasite containing certain information concerning the Company and its product candidates. From March 30 through May 1, 2015, Alexion and its representatives engaged in due diligence review of the Company.

Also on March 30, 2015, Mr. Patel and other members of the Company’s senior management met with Mr. Hallal and other members of Alexion’s senior management. At this meeting, the Company provided to Alexion certain information concerning the Company and its product candidates. In telephone conversations on March 31, 2015 and April 1, 2015, Dr. Bell provided feedback from the diligence review and Dr. Baker requested that Alexion provide any revisions to Alexion’s $212 Proposal early in the week of April 6, 2015.

On April 2, 2015, the Company Board held a meeting to discuss the status of discussions between the Company and Alexion. Representatives of Ropes & Gray attended the meeting. The members of the Company Board discussed the status of discussions among themselves, and discussed the advisability of causing the Company’s senior management to continue its engagement with Alexion during a critical juncture in the Company’s regulatory and launch process for the Company’s lead product candidate.

In a telephone conversation on April 8, 2015, Dr. Bell requested additional time to formulate Alexion’s communication to the Company Board, and Dr. Baker requested that Alexion provide its communication by the end of that week.

On April 9, 2015, the Company Board held a meeting to discuss the status of communications between the Company and Alexion. Representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray attended the meeting. Dr. Baker and Mr. Patel updated the Company Board on the status of the discussions and thereafter members of the Company Board discussed the potential transaction with Alexion among themselves and with representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray.

On April 12, 2015, Dr. Bell telephoned Dr. Baker to reiterate Alexion’s interest in acquiring the Company for $212 per share, to be paid 60% in cash and 40% in the form of Alexion common stock (“Alexion’s

 

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Reconfirmed $212 Proposal”). Dr. Bell subsequently sent Dr. Baker a letter containing Alexion’s Reconfirmed $212 Proposal, which Dr. Baker distributed to the members of the Company Board. In the letter, Alexion invited Dr. Baker to serve on the Alexion Board following completion of the transaction between the parties.

On April 13, 2015, the Company Board held a meeting to discuss Alexion’s Reconfirmed $212 Proposal. Representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray attended the meeting. The members of the Company Board discussed Alexion’s Reconfirmed $212 Proposal among themselves and with representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. Following this discussion, it was the consensus of the Company Board that Dr. Baker should communicate to Dr. Bell that the proposed price contained in Alexion’s Reconfirmed $212 Proposal did not appear compelling in light of what they believed the Company’s standalone value to be and that, accordingly, the Company was not interested in engaging in a potential transaction with Alexion on the terms outlined in Alexion’s Reconfirmed $212 Proposal. Later that day, Dr. Baker so informed Dr. Bell.

On April 16, 2015, Dr. Bell telephoned Dr. Baker to communicate Alexion’s interest in acquiring the Company for $230 per share, with the transaction consideration to be comprised of 50% cash and 50% Alexion common stock (“Alexion’s $230 Proposal”), which represented a premium of approximately 132.6% to the Company’s closing price on February 17, 2015, which was the day prior to the date Alexion provided Alexion’s $175 Proposal, a premium of approximately 112.5% to the Company’s volume-weighted average closing price for the 30 days prior to the date Alexion provided Alexion’s $175 Proposal and a premium of approximately 90.2% to the Company’s all-time high closing price. Dr. Bell stated that this would be Alexion’s final offer and that Alexion would not bid higher. Dr. Bell stated that in order to proceed with Alexion’s $230 Proposal, Alexion would need to receive and be satisfied with additional information concerning the Company. Dr. Bell subsequently sent Dr. Baker a letter confirming that Alexion’s $230 Proposal was Alexion’s best and final offer, which Dr. Baker distributed to the members of the Company Board.

On April 17, 2015, the Company Board held a meeting to discuss Alexion’s $230 Proposal. The meeting was also attended by representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. The members of the Company Board discussed Alexion’s $230 Proposal among themselves and with representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. While not coming to a conclusion on whether to do so, the members of the Company Board discussed, in light of the discussions with Alexion, whether the Company should solicit the interest of other potentially interested counterparties in a potential transaction with the Company and the risks attendant to doing so, including the increased potential for leaks of information and the associated risks, the lack of senior management bandwidth during a critical juncture in the Company’s regulatory and launch process with respect to its lead product candidate, and the incremental diversion of employee time and attention associated with interacting with multiple potential counterparties. Representatives of Goldman Sachs discussed with the Company Board the paucity of potentially interested and capable counterparties based on the criteria of whether such parties had both the capacity to compete with the terms proposed by Alexion and the demonstrated interest in the Company’s area of interest. Following this discussion, it was the consensus of the Company Board that Dr. Baker should communicate to Dr. Bell that the Company was willing to explore a transaction with Alexion on the terms contained in Alexion’s $230 Proposal, that the Company believed that its large stockholders would support such a transaction, that the Company was willing to provide to Alexion certain additional information concerning the Company but also that the Company and its advisors would require access to certain information regarding Alexion in order to determine whether the significant stock component contained in Alexion’s $230 Proposal was acceptable. On April 18, 2015, Dr. Baker so informed Dr. Bell.

On April 19, 2015, representatives of Wachtell Lipton provided to representatives of Sullivan & Cromwell a draft transaction agreement providing for a two-step process in which Alexion would conduct an exchange offer to be followed by a short-form merger, together with a draft support agreement to be entered into by certain stockholders specified by Alexion.

 

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From April 20 through May 1, 2015, the parties, primarily through their external legal counsel (Sullivan & Cromwell for the Company and Wachtell Lipton for Alexion) negotiated the transaction documentation and the significant transaction terms. The issues resolved between the parties during this period included issues relating to certainty of consummation of the transaction and the definition of “Material Adverse Effect” to be used in the transaction agreement; the Company board’s flexibility to change its recommendation of the transaction; and the ability of the Company Board to terminate the transaction agreement in order to accept a superior proposal from a third party. The parties also agreed on a structure for the transaction whereby the exchange offer to be followed by a short-form merger (if the offer conditions were satisfied) was to be pursued, with an option for Alexion to elect to terminate the exchange offer if any of the offer conditions had not been met after July 12, 2015 and proceed alternatively by having the Company call a meeting of its stockholders to vote to approve the transaction agreement.

During the week of April 20, 2015, representatives of Wachtell Lipton furnished to representatives of Sullivan & Cromwell a draft confidentiality agreement incorporating a two-year standstill provision pursuant to which the Company would be prohibited from taking certain actions with respect to Alexion for such period. Representatives of Sullivan & Cromwell and Wachtell Lipton negotiated this confidentiality agreement, which was entered into by the Company and Alexion as of April 22, 2015. On that date, Alexion made available to the Company certain information concerning Alexion.

On April 24, 2015, Mr. Hallal and other representatives of Alexion met in person with senior management and other representatives of the Company during which Alexion provided to the Company certain information concerning Alexion’s business, financial position, products and product candidates.

On April 26, 2015, the Company Board held a meeting to discuss the status of the negotiations and of the parties’ respective due diligence investigations. The meeting was also attended by representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. The members of the Company Board discussed the potential transaction with Alexion among themselves and with representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. In connection with this discussion, the Company Board considered whether the Company should solicit interest from other potential counterparties regarding a potential transaction with the Company. Members of the Company Board and representatives of Goldman Sachs discussed the paucity of potentially interested counterparties based on the criteria of whether that such parties had both the capacity to compete with the terms proposed by Alexion and the demonstrated interest in the Company’s area of interest. Following this discussion, and based on the economic terms of Alexion’s $230 Proposal, the risks associated with contacting other potentially interested parties, including the increased potential for leaks of information and the associated risks, the appropriate allocation of senior management bandwidth during a critical juncture in the Company’s regulatory and launch process for the Company’s lead product candidate, the incremental diversion of employee time and attention associated with interacting with multiple potential counterparties, the Company Board’s and Goldman Sachs’s views concerning the likelihood that contacting additional parties would generate proposals with values exceeding Alexion’s $230 Proposal and the Company Board’s intention to ensure that any transaction agreement with Alexion would permit the Company Board to terminate the transaction agreement in order to accept a superior proposal from a third party, the Company Board determined not to direct the Company management to contact other potentially interested parties. Members of the Company Board also discussed the importance of determining expeditiously whether a mutually agreeable agreement with respect to a transaction could be reached with Alexion, and instructed Dr. Baker to inform Dr. Bell that the Company wanted to reach this determination by May 4, 2015. On April 26, 2015, Dr. Baker so informed Dr. Bell.

On April 29, 2015, the Company Board held a meeting to discuss the status of the negotiations and the provisions of the draft transaction agreement. The meeting was also attended by representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. Among other things, the Company Board emphasized to its negotiating representatives the importance of maintaining flexibility for the Company Board to change its recommendation of the transaction under appropriate circumstances.

 

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On May 2, 2015, Dr. Bell and Dr. Baker spoke by telephone, and Dr. Bell stated, among other things, that Alexion expected its due diligence investigation to require several more days, and potentially up to one additional week. Dr. Baker stated that he believed the Company Board would not be willing to delay signing and announcement of the transaction for any additional period, but that if Alexion were willing to move forward without delay, the Company would be willing to consider including in the transaction agreement certain post-signing provisions concerning certain regulatory and other matters relating to the Company’s product candidates. Later on May 2, 2015, the Company Board held a meeting to discuss the status of the negotiations. The meeting was also attended by representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. The Company Board discussed the status of the negotiations, and directed Dr. Baker to terminate discussions with Alexion unless Alexion committed to moving forward on a more expeditious timeline. Following this meeting, Dr. Bell and Dr. Baker spoke by telephone, and agreed to terminate discussions between the parties.

On May 4, 2015, Dr. Bell telephoned Dr. Baker and stated that he had discussed matters with the Alexion Board, including the Company’s willingness to consider certain post-signing provisions with regard to certain regulatory and lead product matters, and that Alexion would be willing to move forward to negotiate and finalize documentation for the potential transaction in time for a public announcement on May 6, 2015. At Dr. Baker’s request, Dr. Bell confirmed to Dr. Baker that it was a requirement for Alexion that Dr. Baker agree to be appointed to the Alexion Board following consummation of the transaction between the parties.

On May 4, 2015, the Company Board held a meeting to discuss the communication from Dr. Bell. Following discussion among the members of the Company Board, the Company Board directed Dr. Baker and the Company’s management and advisors to resume discussions with Alexion.

Late on May 4, 2015, representatives of Wachtell Lipton provided representatives of Sullivan & Cromwell with a revised draft of the transaction agreement. Representatives of Sullivan & Cromwell and Wachtell Lipton negotiated the transaction agreement over the night of May 4, 2015 and the morning of May 5, 2015. On the morning of May 5, 2015, Dr. Bell and Dr. Baker spoke by telephone to discuss the few remaining open negotiation points.

In the late afternoon on May 5, 2015, the Company Board held a meeting to discuss the status of the negotiations. The meeting was also attended by representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. In this meeting, the Company management updated the Company Board concerning the Company’s due diligence investigation concerning Alexion, and representatives of Goldman Sachs provided the Company Board with a financial review of Alexion.

In the evening of May 5, 2015, representatives of Sullivan & Cromwell and Wachtell Lipton continued to negotiate the transaction agreement.

Later in the evening on May 5, 2015, the Company Board again held a meeting. The meeting was also attended by representatives of Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. Representatives of Sullivan & Cromwell reviewed the terms of the proposed transaction agreement with the members of the Company Board and a representative of Sullivan & Cromwell described the directors’ fiduciary duties. Representatives of Goldman Sachs presented Goldman Sachs’s financial analysis of the proposed transaction consideration and rendered to the Company Board its oral opinion, subsequently confirmed in writing, that as of May 5, 2015, and based upon and subject to the assumptions made, procedures followed, matters considered and limitations on the scope of the review undertaken by Goldman Sachs as set forth in such written opinion, the consideration to be paid to the holders of Shares pursuant to the Merger Agreement was fair from a financial point of view to such holders, as discussed below in “— Opinion of the Company’s Financial Advisor.” Such opinion is attached to this Schedule 14D-9 as Annex A.

Following consideration of the transaction agreement and the transactions contemplated by the transaction agreement, the Board unanimously (i) approved and declared advisable the Transaction Agreement, the Offer, the Mergers and the other transactions contemplated by the Transaction Agreement; (ii) determined that the terms of

 

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the Transaction Agreement, the Offer, the Mergers and the other transactions contemplated by the Transaction Agreement were fair to and in the best interests of the Company and to the Company stockholders; (iii) authorized and approved the Transaction Agreement, the Offer, the Mergers the other transactions contemplated by the Transaction Agreement; and (iv) recommended that the Company stockholders accept the offer, tender their shares of the Company common stock into the Offer and, if a vote of the Company stockholders is required by applicable law to consummate the First Merger, adopt the Transaction Agreement at a meeting of the Company stockholders duly called and held for such purpose. During the meeting of the Company Board, the compensation committee of the Company Board reviewed the terms of, and approved, certain of the Company employment compensation, severance and other employee benefit arrangements with respect to the employees of the Company.

After the closing of trading on the NASDAQ Stock Market on May 5, 2015, the Company, Alexion, Offeror, and Merger Sub executed the Transaction Agreement, Alexion and certain stockholders of the Company executed the voting and support agreements, and on May 6, 2015, the Company and Alexion issued a joint press release announcing the execution of the Transaction Agreement, the voting and support agreements and the forthcoming commencement of the exchange offer. The press release is filed as Exhibit (e)(5)(A) to this Schedule 14D-9, and is hereby incorporated herein by reference.

On May 22, 2015, the Offeror commenced the offer, and the Company filed this Schedule 14D-9.

Reasons for the Recommendation of the Company Board

In evaluating the Transaction Agreement and the Offer, the Mergers and the other transactions contemplated by the Transaction Agreement, including the Voting and Support Agreements, the Company Board consulted with the senior management of the Company, as well as Goldman Sachs, Sullivan & Cromwell and Ropes & Gray. In the course of making the determination that the Transaction Agreement and the Offer, the Mergers and the other transactions contemplated by the Transaction Agreement, including the Voting and Support Agreements, are fair to and in the best interests of the Company and its stockholders and to recommend that Company’s stockholders accept the Offer and tender their Shares into the Offer, the Company Board considered numerous factors, including the following non-exhaustive list of material factors and benefits of the Offer and the Mergers, each of which the Company Board believed supported its unanimous determination and recommendation:

 

    Transaction Consideration. The Company Board considered the fact that the Transaction Consideration implied a total value per Share of $230 based on the nine day volume-weighted average closing price of Alexion common stock through May 5, 2015 and:

 

    that this total value per Share:

 

    represents a 139.9% premium to the trading price at which the Shares closed on May 5, 2015, the last trading day before date of the announcement of the Transaction Agreement;

 

    represents a 132.0% premium over the volume-weighted average closing price for the Shares for the 30-calendar day period ending immediately before the date of announcement of the Transaction Agreement;

 

    represents a 90.2% premium to the highest closing price for the Shares during the last 12 months before the date of announcement of the Transaction Agreement; and

 

    exceeded the all-time high trading price of the Shares; and

 

    the Company Board considered that in its view it had obtained Alexion’s and Offeror’s best and final offer, and that, as of the date of the Transaction Agreement, the Transaction Consideration represented the highest per-Share consideration reasonably obtainable.

 

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    Business and Financial Condition of the Company. The Company Board considered the Company’s business, financial condition, results of operations, business, competitive position, properties, assets and prospects as well as its long-range plan. The Company Board considered, among other factors that the holders of the Shares would continue to be subject to the risks and uncertainties of the Company executing on its long-range plan if it remained independent. These risks and uncertainties included risks relating to potential difficulties and delays in obtaining regulatory and marketing approval for its lead product, Kanuma™ (sebelipase alfa); potential difficulties and delays in clinical trials of product candidates; regulatory developments involving current and future products and product candidates; and other risks inherent to its long-range plan. The Company Board weighed the certainty of realizing a compelling value for Shares in the Offer and the Mergers compared to the uncertainty that trading values would approach the Transaction Consideration in the foreseeable future and the substantial risk and uncertainty associated with the Company and its business as a clinical-stage pharmaceutical company (including the risk factors set forth in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2014, subsequent quarterly reports on Form 10-Q and current reports on Form 8-K).

 

    Strategic Alternatives. The Company Board considered its belief that the value offered to holders of Shares in the Offer and the Mergers was more favorable to holders of Shares than the potential value of remaining an independent public company.

 

    Goldman Sachs’s Fairness Opinion and Related Analyses. The Company Board considered the opinion of Goldman Sachs delivered to the Company Board on May 5, 2015, which was confirmed by delivery of a written opinion dated May 5, 2015, to the effect that, as of such date and based upon and subject to the assumptions made, procedures followed, matters considered and limitations on the review undertaken by Goldman Sachs in connection with its opinion, the Transaction Consideration to be paid to the holders of the outstanding Shares pursuant to the Transaction Agreement was fair, from a financial point of view, to such holders, as more fully described below under the caption “— Opinions of the Financial Advisor to the Company Board.”

 

    Paucity of Potentially Interested Counterparties. After discussions with Goldman Sachs and management of the Company, the Company Board considered the paucity of potentially interested and capable counterparties based on the criteria of whether such parties both had the capacity to compete with the terms proposed by Alexion and the demonstrated interest in the Company’s area of interest.

 

    Negotiation Process and Procedural Fairness. The Company Board considered the fact that the terms of the Offer and Mergers were the result of robust arm’s-length negotiations conducted by the Company, with the knowledge and at the direction of the Company Board, and with the assistance of independent financial and legal advisors.

 

    Type of Consideration. The Company Board considered the forms of consideration to be paid to the Company’s stockholders as a combination of cash and shares of Alexion common stock, which with respect to the cash consideration, allows holders of Shares to realize immediate value, in cash, for their investment in the Company, while avoiding the Company’s significant business risks, and with respect to the stock consideration, provides holders of Shares with the ability to participate in the future growth of Alexion.

 

    Speed of Completion. The Company Board considered the anticipated timing of the consummation of the transactions contemplated by the Transaction Agreement, and the structure of the transaction as an exchange offer for the Shares, which subject to the satisfaction or waiver of the applicable conditions set forth in the Transaction Agreement, should allow stockholders to receive the consideration for their Shares in a relatively short time frame, followed by the First Merger in which stockholders who do not validly exercise appraisal rights will receive the same consideration as received by those stockholders who tender their Shares in the Offer. The Company Board considered that the potential for closing in a relatively short time frame could also reduce the amount of time in which the Company’s business would be subject to the potential disruption and uncertainty pending closing.

 

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    Certain Company Management Projections. The Company Board considered certain limited prospective forecasts for the Company prepared by Company management, which reflect an application of various commercial assumptions of the Company’s senior management to the latest available long-range plans of the Company. For further discussion, see “Item 8. Additional Information—Certain Company Management Projections.”

 

    Likelihood of Completion; Certainty of Payment. The Company Board considered its belief that the Offer and the Mergers will likely be consummated, based on, among other factors:

 

    the absence of any financing condition to consummation of the Offer or the Mergers;

 

    the reputation and financial condition of Alexion;

 

    the commitments by Bank of America, N.A., JPMorgan Chase Bank, N.A., Merrill Lynch, Pierce, Fenner & Smith Incorporated and J.P. Morgan Securities LLC to lend cash to Alexion for the purposes of financing the Offer and the Mergers;

 

    the fact that the conditions to the Offer and Mergers are specific and limited in scope;

 

    the Company’s ability to request the Delaware Court of Chancery to specifically enforce the Transaction Agreement, including the consummation of the Offer and the Mergers; and

 

    the ability of the parties to, under certain circumstances, elect to pursue completion of the transactions through a long-form merger subject to a stockholder vote rather than through an exchange offer followed by a back-end, short-form merger.

 

    Other Terms of the Transaction Agreement. The Company Board considered other terms of the Transaction Agreement, which are more fully described in the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement.” Certain provisions of the Transaction Agreement that the Company Board considered important included:

 

    Minimum Tender Condition. Consummation of the Offer is conditioned on the satisfaction of the minimum tender condition, which, if satisfied, would demonstrate strong support for the Offer and the Mergers by holders of Shares because satisfaction of the minimum tender condition would require that at least a majority of Shares would have been tendered in the Offer and not withdrawn.

 

    Ability to Respond to Unsolicited Takeover Proposals. Prior to the time of the Offeror’s acceptance of Shares tendered in the Offer or, if applicable, the receipt of the Company stockholder approval, the Company Board may provide confidential information and/or engage in discussions or negotiations in connection with an unsolicited bona fide written takeover proposal (for further discussion, see the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement—No Solicitation of Other Offers by Synageva”) that did not result from the Company’s knowing or intentional breach of its non-solicitation obligations if the Company Board determines in good faith, after consultation with its independent financial advisor and outside legal counsel, that such takeover proposal constitutes or is reasonably likely to lead to a superior proposal (for further discussion, see the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement—No Solicitation of Other Offers by Synageva”) and that the failure to take such action would be inconsistent with the directors’ fiduciary duties under applicable law, subject to certain notice requirements in favor of Alexion and the entry into an acceptable confidentiality agreement.

 

   

Company Adverse Recommendation Change in Response to a Company Superior Proposal; Ability to Accept a Company Superior Proposal. The Company Board may, in connection with a superior proposal, effect a change in recommendation (for further discussion, see the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement—No Solicitation of Other

 

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Offers by Synageva”) and/or cause the Company to terminate the Transaction Agreement to enter into a definitive agreement with respect to a superior proposal, if the Company Board determines in good faith, after consultation with its independent financial advisor and outside legal counsel, that failure to take such action would be inconsistent with the directors’ fiduciary duties under applicable law, subject to a four-business day “match right” that would allow Alexion to match a superior proposal, and which will renew for two additional business days with any revisions to the financial terms or any material revisions to the other terms of the superior proposal. If the Transaction Agreement is terminated by the Company in connection with the Company’s entering into a definitive agreement with respect to a superior proposal, then the Company will have an obligation to pay Alexion a termination fee of $325 million (as more fully described in the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement—Termination Fee”).

 

    General Company Adverse Recommendation Change. The Company Board may also effect a change in recommendation other than in response to a superior proposal if the Company Board determines in good faith, after consultation with its independent financial advisor and outside legal counsel, that failure to take such action would be inconsistent with the directors’ fiduciary duties under applicable law, subject to a four-business day right that would allow Alexion to make such adjustments to the terms and conditions of the Transaction Agreement such that the failure to take such action would no longer be inconsistent with the directors’ fiduciary duties under applicable law. If Alexion terminates the Transaction Agreement as a result of such adverse change in recommendation, the Company will have an obligation to pay Alexion a termination fee of $325 million (as more fully described in the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement—Termination Fee”).

 

    Extension of the Offer. The Offeror’s obligation to accept and pay for all Shares that have been validly tendered into the Offer and not properly withdrawn is subject to the satisfaction or waiver of a number of conditions, which we refer to as the conditions to the offer. However, the Offeror is required, under certain circumstances, to extend the Offer beyond the initial expiration date (see the section of the Prospectus/Offer to Exchange entitled “Exchange Offer Procedures—Extension, Termination and Amendment of Offer”).

 

    Stockholder Vote Election. Under certain circumstances, the Transaction Agreement permits the use of a one-step, “long-form” merger after a certain date, with the First Merger occurring following the approval of the Transaction Agreement by the Company’s stockholders, which may in certain circumstances be more expedient than the two-step transaction involving the Offer and back-end First Merger.

 

    End Date. The end date (as defined in the section of the Prospectus/Offer to Exchange entitled “Questions and Answers About the Offer”) under the Transaction Agreement on which either party, subject to certain exceptions, can terminate the Transaction Agreement allows for sufficient time to consummate the Offer and the Mergers, while minimizing the length of time during which the Company would be required to operate subject to the restrictions on interim operations set forth in the Transaction Agreement.

 

    Cooperation. The Transaction Agreement requires Alexion to use its reasonable best efforts to consummate the Offer and the Mergers, and sets forth agreed actions with respect to Alexion’s obligations to obtain requisite approvals to consummate the Offer and the Mergers.

 

    Appraisal Rights. The Company Board considered the availability of statutory appraisal rights under Delaware law in connection with the First Merger for stockholders of the Company who do not tender their Shares into the Offer (and who otherwise comply with the statutory requirements of Delaware law), and who believe that exercising such rights would yield them a greater per-Share amount than the Transaction Consideration, which appraisal rights avoid delays in the transaction so that other stockholders of the Company will be able to receive in the Offer and the First Merger the Transaction Consideration, as applicable, for their Shares.

 

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    In reaching its determinations and recommendations described above, the Company Board also considered the following potentially negative factors:

 

    Non-Solicitation Covenant. The Company Board considered that the Transaction Agreement prohibits the Company from soliciting takeover proposals from third parties (as more fully described in the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement—No Solicitation of Other Offers by Synageva”).

 

    Termination Fee. The Company Board considered the fact that the Company must pay Alexion a termination fee of $325 million if the Transaction Agreement is terminated under certain circumstances, including to accept a superior proposal, and that the amount of the termination fee is comparable to termination fees in transactions of a similar size, was reasonable, would not likely deter competing bids and would not likely be required to be paid unless the Company entered into a more favorable transaction. The Company Board also recognized that the provisions in the Transaction Agreement relating to these fees were insisted upon by Alexion as a condition to entering into the Transaction Agreement (as more fully described in the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement—Termination Fee”).

 

    Interim Operating Covenants. The Company Board considered that the Transaction Agreement imposes restrictions on the conduct of the Company’s business prior to the consummation of the Mergers, requiring the Company to conduct its and its subsidiaries’ business in the ordinary course of business in all material respects and use reasonable best efforts to maintain and preserve intact their business organizations, maintain satisfactory relationships with governmental entities, customers and suppliers and keep available the services of their key employees, and that may limit the Company and its subsidiaries from taking specified actions, subject to specific limitations, which may delay or prevent the Company from undertaking business opportunities that may arise pending completion of the transactions (as more fully described in the section of the Prospectus/Offer to Exchange entitled “Transaction Agreement—Conduct of Business During Pendency of the Transactions”).

 

    Risks the Offer and the Mergers May Not Be Completed. The Company Board considered the risk that the conditions to the Offer may not be satisfied and that, therefore, Shares may not be purchased pursuant to the Offer and the Mergers may not be consummated. The Company Board also considered the risks and costs to the Company if the Offer and the Mergers are not consummated, including the diversion of management and employee attention, potential employee attrition, the potential effect on vendors, distributors, customers, partners and others that do business with the Company and the potential effect on the trading price of the Shares.

 

    Potential Conflicts of Interest. The Company Board considered the fact that the Company’s executive officers and directors have financial interests in the transactions contemplated by the Transaction Agreement, including the Offer and the Mergers that may be different from or in addition to those of other stockholders, as more fully described in “Item 3. Past Contacts, Transactions, Negotiations and Agreements — Arrangements with Current Executive Officers and Directors of the Company.”

The foregoing discussion of the factors considered by the Company Board is intended to be a summary, and is not intended to be exhaustive, but rather includes the principal factors considered by the Company Board. After considering these factors, the Company Board concluded that the positive factors relating to the Transaction Agreement and the transactions contemplated thereby, including the Offer and the Mergers, substantially outweighed the potential negative factors. The Company Board collectively reached the conclusion to approve the Transaction Agreement and the related transactions, including the Offer and the Mergers, in light of the various factors described above and other factors that the members of the Company Board believed were appropriate. In view of the wide variety of factors considered by the Company Board in connection with its evaluation of the Transaction Agreement and the transactions contemplated thereby, including the Offer and the

 

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Mergers, and the complexity of these matters, the Company Board did not consider it practical, and did not attempt to quantify, rank or otherwise assign relative weights to the specific factors it considered in reaching its decision, and it did not undertake to make any specific determination as to whether any factor, or any particular aspect of any factor, supported or did not support its ultimate determination. Rather, the Company Board made its recommendation based on the totality of information it received and the investigation it conducted. In considering the factors discussed above, individual directors may have given different weights to different factors.

(c) Intent to Tender.

To the best of the Company’s knowledge, after reasonable inquiry, each executive officer and director of the Company who owns Shares, other than Dr. Baker and Dr. Biggar, presently intends to tender in the Offer all Shares that he or she owns of record or beneficially. The foregoing does not include any Shares over which, or with respect to which, any such executive officer or director acts in a fiduciary or representative capacity or is subject to the instructions of a third party with respect to such tender. Dr. Baker, Dr. Bigger and investment funds advised by an adviser affiliated with Dr. Baker (the “Funds”) currently intend not to tender such Shares in the Offer and instead seek to have their Shares converted into the right to receive the Merger Consideration in the First Merger. The Funds, however, have advised the Company that they reserve the right to tender into the Offer, depending on the adviser’s evaluation of the surrounding facts and circumstances. The Funds have also advised the Company that they are supportive of the Transaction Agreement, the Offer and the Merger, and the Funds have entered into a Voting and Support Agreement with Alexion and Offeror, pursuant to which, such stockholders agreed, among other things, to vote all Shares beneficially owned by such stockholders, in favor of the adoption of the Transaction Agreement and the approval of the transactions contemplated by the Transaction Agreement, including the First Merger, and any other matter necessary to consummate such transactions, and not to vote in favor of, or tender their Shares into, any competing offer or takeover proposal. FBB Associates has advised the Company that it has not yet made a decision to tender, hold or dispose, whether by sale, charitable gift or otherwise, its Shares.

(d) Opinions of the Financial Advisor to the Company Board

Opinion of Goldman Sachs

At a meeting of the Company Board, Goldman Sachs rendered its oral opinion to the Company Board, subsequently confirmed in writing, to the effect that, as of May 5, 2015, and based upon and subject to the factors and assumptions set forth in Goldman Sachs’s written opinion, the $115 in cash and 0.6581 shares of Alexion common stock to be paid to the holders of Shares pursuant to the Transaction Agreement was fair from a financial point of view to those holders.

The full text of the written opinion of Goldman Sachs, dated May 5, 2015, which sets forth the assumptions made, procedures followed, matters considered, qualifications and limitations on the review undertaken in connection with the opinion, is attached to this Schedule 14D-9 as Annex A. The summary of the Goldman Sachs opinion contained in this Schedule 14D-9 is qualified in its entirety by reference to the full text of Goldman Sachs’s written opinion. Goldman Sachs’s advisory services and opinion were provided for the information and assistance of the Company Board in connection with its consideration of the transactions contemplated by the Transaction Agreement and the opinion does not constitute a recommendation as to whether or not any holder of Shares should tender such Shares in connection with the Offer, vote with respect to the proposed First Merger, if applicable, or any other matter.

In connection with rendering its opinion described above and performing its related financial analyses, Goldman Sachs reviewed, among other things:

 

    the Transaction Agreement;

 

    annual reports to stockholders and Annual Reports on Form 10-K of the Company and Alexion for the five fiscal years ended December 31, 2014;

 

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    certain interim reports to stockholders and Quarterly Reports on Form 10-Q of the Company and Alexion;

 

    certain other communications from the Company and Alexion to their respective stockholders;

 

    certain publicly available research analyst reports for the Company and Alexion; and

 

    certain internal financial analyses and forecasts for the Company and certain financial analyses and forecasts for Alexion, in each case as prepared by management of the Company and approved for Goldman Sachs’s use by the Company, which are referred to as the “Forecasts”, and certain operating synergies projected by management of the Company to result from the Transaction, as approved for Goldman Sachs’s use by the Company which are referred to as the “Synergies”.

Goldman Sachs also held discussions with members of the senior management of the Company and Alexion regarding their assessment of the strategic rationale for, and the potential benefits of, the transaction contemplated by the Agreement, the past and current business operations, financial condition and future prospects of Alexion and with members of the senior management of the Company regarding their assessment of the past and current business operations, financial condition and future prospects of the Company; reviewed the reported price and trading activity for the Shares and Alexion common stock; compared certain financial and stock market information for the Company and Alexion with similar information for certain other companies the securities of which are publicly traded; reviewed the financial terms of certain recent business combinations in the biopharmaceutical industry; and performed such other studies and analyses, and considered such other factors, as Goldman Sachs deemed appropriate.

For purposes of rendering its opinion, Goldman Sachs, with the consent of the Company, relied upon and assumed the accuracy and completeness of all of the financial, legal, regulatory, tax, accounting and other information provided to, discussed with or reviewed by, it, without assuming any responsibility for independent verification thereof. In that regard, Goldman Sachs assumed, with the consent of the Company, that the Forecasts and the Synergies had been reasonably prepared on a basis reflecting the best currently available estimates and judgments of the Company’s management. Goldman Sachs had not made an independent evaluation or appraisal of the assets and liabilities (including any contingent, derivative or other off-balance-sheet assets and liabilities) of the Company or Alexion or any of their respective affiliates and Goldman Sachs had not been furnished with any such evaluation or appraisal. Goldman Sachs assumed that all governmental, regulatory or other consents and approvals necessary for the consummation of the transactions contemplated by the Transaction Agreement would be obtained without any adverse effect on the Company or Alexion or on the expected benefits of the transactions in any way meaningful to its analysis. Goldman Sachs assumed that the transactions would be consummated on the terms set forth in the Transaction Agreement, without the waiver or modification of any term or condition the effect of which would be in any way meaningful to its analysis.

Goldman Sachs’s opinion did not address the underlying business decision of the Company to engage in the transactions contemplated by the Transaction Agreement, or the relative merits of the transactions as compared to any strategic alternatives that may be available to the Company; nor did it address any legal, regulatory, tax or accounting matters. Goldman Sachs was not requested to solicit, and did not solicit, interest from other parties with respect to an acquisition of, or other business combination with, the Company or any other alternative transaction. Goldman Sachs’s opinion addresses only the fairness from a financial point of view to the holders of Shares, as of the date of its opinion, of the $115 in cash and 0.6581 shares of Alexion common stock per Share to be paid to those holders pursuant to the Transaction Agreement. Goldman Sachs did not express any view on, and its opinion did not address, any other term or aspect of the Transaction Agreement or the transactions or any term or aspect of any other agreement or instrument contemplated by the Transaction Agreement or entered into or amended in connection with the transaction, including, the fairness of the transactions to, or any consideration received in connection therewith by, the holders of any other class of securities, creditors, or other constituencies of the Company; nor as to the fairness of the amount or nature of any compensation to be paid or payable to any of the officers, directors or employees of the Company, or class of such persons, in connection with the

 

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transaction, whether relative to the $115 in cash and 0.6581 shares of Alexion common stock per Share to be paid to the holders of Shares pursuant to the Transaction Agreement or otherwise. Goldman Sachs did not express any opinion as to the impact of the transactions on the solvency or viability of the Company, or Alexion or the ability of the Company or Alexion to pay their respective obligations when they come due. Goldman Sachs’s opinion was necessarily based on economic, monetary, market and other conditions as in effect on, and the information made available to Goldman Sachs as of, the date of its opinion and Goldman Sachs assumed no responsibility for updating, revising or reaffirming its opinion based on circumstances, developments or events occurring after the date of the opinion. Goldman Sachs’s advisory services and its opinion were provided for the information and assistance of the Company Board in connection with its consideration of the transactions contemplated by the Transaction Agreement and its opinion does not constitute a recommendation as to whether or not any holder of Shares should tender such Shares in connection with the Offer, how any holder of Shares should vote with respect to the proposed First Merger, if applicable, or any other matter. Goldman Sachs’s opinion was approved by a fairness committee of Goldman Sachs.

Summary of Financial Analyses.

The following is a summary of the material financial analyses presented by Goldman Sachs to the Company Board in connection with rendering its opinion described above. The following summary, however, does not purport to be a complete description of the financial analyses performed by Goldman Sachs, nor does the order of analyses described represent relative importance or weight given to those analyses by Goldman Sachs. Some of the summaries of the financial analyses include information presented in tabular format. The tables must be read together with the full text of each summary and are alone not a complete description of Goldman Sachs’s financial analyses. Except as otherwise noted, the following quantitative information, to the extent that it is based on market data, is based on market data as it existed on or before May 5, 2015 and is not necessarily indicative of current market conditions.

For purposes of its analyses, Goldman Sachs calculated an implied price per Share to be paid to the holders of Shares pursuant to the Transaction Agreement based on the closing price for the Alexion common stock of $168.55 on May 5, 2015 by adding the $115 in cash to an implied value for 0.6581 shares of Alexion common stock (determined by multiplying 0.6581 by the May 5, 2015 closing price for the Alexion common stock) to derive an implied price per Share in the transaction of $225.92. It was also noted that, based on the volume-weighted average closing price of Alexion common stock over the nine trading day period ending May 5, 2015 of $174.75, the implied price per Share to be paid to the holders of Shares pursuant to the Transaction Agreement was $230.00.

Illustrative Whole Company Discounted Cash Flow Analysis.

Goldman Sachs performed a discounted cash flow analysis of the Company as whole to derive a range of illustrative present values per Share. Using discount rates ranging from 10.5% to 12.5%, reflecting an estimate of the Company’s weighted average cost of capital, Goldman Sachs discounted to present value as of March 31, 2015, (i) estimates of the unlevered free cash flow to be generated by the Company during the period from April 1, 2015 through 2030 reflected in the Forecasts, and (ii) a range of illustrative terminal values for the Company as of December 31, 2030 calculated by applying perpetuity growth rates ranging from 1.0% to 3.0% to a terminal year estimate of the unlevered free cash flow to be generated by the Company (reflecting the estimate of the unlevered free cash flow to be generated by the Company in 2030) as reflected in the Forecasts. In addition, using a discount rate of 11.5%, reflecting an estimate of the Company’s cost of equity, Goldman Sachs discounted to present value as of March 31, 2015 the estimated benefits of the Company’s net operating losses, or (“NOLs”) from March 31, 2015 through 2030, as reflected in the Forecasts. Goldman Sachs derived ranges of illustrative enterprise values for the Company by adding the ranges of present values it derived based on the estimated unlevered free cash flows of the Company for the period from April 1, 2015 through 2030, the ranges of present value it derived based on the illustrative terminal values for the Company as of December 31, 2030 and the present value is derived for the estimated benefits of the Company’s NOLs for the period from April 1,

 

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2015 through 2030. Goldman Sachs subtracted from the range of illustrative enterprise values it derived for the Company an illustrative amount of cash and short term investments of the Company as of March 31, 2015 (derived by adding the amount of the Company’s cash and short term investments as of March 31, 2015 plus $200 million in cash estimated by the Company management to be raised in an equity offering contemplated for 2015 by the Forecasts, which are referred to as the “Contemplated Offering”) to derive a range of illustrative equity values for the Company as of March 31, 2015. Goldman Sachs then divided the range of illustrative equity values it derived by an implied number of fully diluted outstanding Shares (calculated on a treasury method basis based on information provided by Company management and reflecting Shares estimated to be issued in the Contemplated Offering) to derive a range of illustrative present values per Share ranging from $165.39-$256.48.

Goldman Sachs also performed a sensitivity analysis to analyze the implied impact on the midpoint of range of illustrative present values per Share it derived as described above of changes in the Company’s management’s assumptions and forecasts with respect to the Company’s product candidates, including changes to assumed pricing, diagnosis rates, probability of success (“PoS”), tax rate, the number of investigational new drug applications (“INDs”) submitted by the Company from 2017 onwards and peak sales per drug launched from the Company’s product development platform. The following table presents the results of this analysis.

 

    

Impact on Illustrative Value per Share

Kanuma LAL-D WW Pricing    $(31.11)/$26.95
Kanuma LAL-D Diagnosis Rate    $(65.91)/$58.48
LAL-Athero Cumulative PoS    $(9.01)/$4.51
LAL-NASH Cumulative PoS    $(0.32)/$0.32
SBC-103 Cumulative PoS    $(9.31)/$6.02
SBC-103 Pricing    $(10.29)
SBC-105 Cumulative PoS    $(25.37)
SBC-105 Pricing    $(26.70)/$10.66
Corporate Tax Rate    $(6.96)/$6.96
Number of INDs per year 2017 onwards    $(5.32)/$10.40
Platform Peak Sales per launched drug    $(2.95)/$20.68

Illustrative Sum-of-the-Parts Discounted Cash Flow Analysis.

Goldman Sachs performed an illustrative sum-of-the-parts discounted cash flow analysis of the Company to derive a range of illustrative values per Share. Using discount rates ranging from 10.5% to 12.5%, reflecting an estimate of the Company’s weighted average cost of capital, Goldman Sachs derived a range of illustrative present values as of March 31, 2015 for each of the Company’s product candidates, Kanuma, SBC-103 and SBC-105, by discounting to present value as of that date estimates of the unlevered free cash flow to be generated by the Company from each Kanuma, SBC-103 and SBC-105 from April 1, 2015 through 2043, as reflected in the Forecasts. Using discount rates ranging from 10.5% to 12.5%, Goldman Sachs also derived a range of illustrative present values as of March 31, 2015 for the Company’s product development platform by discounting to present value as of that date (i) estimates of the unlevered free cash flow to be generated by the Company during the period from April 1, 2015 through 2043 from products (other Kanuma, SBC-103 and SBC-105) to be developed through the Company’s product development platform, as reflected in the Forecasts, and (ii) a range of illustrative terminal values for the Company as of December 31, 2043 calculated by applying perpetuity growth rates ranging from 1.0% to 3.0% to a terminal year estimate of the unlevered free cash flow to be generated by the Company (reflecting the estimate of the unlevered free cash flow to be generated in 2043) from products (other Kanuma, SBC-103 and SBC-105) to be developed through the Company’s product development platform, as reflected in the Forecasts. Goldman Sachs derived ranges of illustrative values per Share as of March 31, 2015 for each of Kanuma, SBC-103, SBC-105 and the Company’s product development platform by dividing the ranges of illustrative present values it derived for each of Kanuma, SBC-103, SBC-105 and the Company’s

 

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product development platform, respectively, by an implied number of fully diluted outstanding Shares (calculated on a treasury method basis based on information provided by Company management and reflecting Shares estimated to be issued in the Contemplated Offering).

Goldman Sachs derived ranges of illustrative values per Share as of March 31, 2015 for the Company’s cash and short term investments by dividing an illustrative amount of cash and short term investments of the Company as of March 31, 2015 (derived by adding the amount of the Company’s cash and short term investments as of March 31, 2015 plus $200 million in cash estimated by the Company management to be raised in the Contemplated Offering) by an implied number of fully diluted outstanding Shares (calculated on a treasury method basis based on information provided by Company management and reflecting Shares estimated to be issued in the Contemplated Offering).

In addition, using a discount rate of 11.5%, reflecting an estimate of the Company’s cost of equity, Goldman Sachs derived a range of illustrative present value as of March 31, 2015 of the Company’s NOLs by discounting to present value as of that date the estimated benefits of the Company’s NOLs from March 31, 2015 through 2043, as reflected in the Forecasts. Using discount rates ranging from 10.5% to 12.5%, Goldman Sachs derived a range of illustrative negative present values as of March 31, 2015 for the Company’s unallocated corporate expenses by discounting to present value as of that date estimates of the Company’s unallocated corporate expenses from April 1, 2015 through the end of 2043, as reflected in the Forecasts. Goldman Sachs derived ranges of illustrative values per Share as of March 31, 2015 for the Company’s NOLs and its unallocated corporate expenses by dividing the ranges of illustrative present values it derived for each by an implied number of fully diluted outstanding Shares (calculated on a treasury method basis based on information provided by Company management and reflecting Shares estimated to be issued in the Contemplated Offering).

The analysis yielded the following ranges of illustrative present values per Share as of May 5, 2015:

 

    

Illustrative Range of Per Share Values

Kanuma

   $90.64 - $111.69

SBC-103

   $14.14 - $19.06

SBC-105

   $39.62 - $53.38

Product Development Platform

   $20.93 - $59.72

Cash & Short-term Investments

   $22.06 - $21.89

NOLs

   $2.53 - $2.51

Unallocated Corporate Expenses

   $(16.37) - $(19.83)

Goldman Sachs added the foregoing ranges to derive a range of illustrative present values per Share from $173.55-$248.43.

 

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Selected Precedent Transactions Analysis.

Goldman Sachs analyzed certain publicly available information relating to the acquisition transactions listed below announced since May 2010 with a transaction value between $1 billion and $20 billion and involving target companies in the biopharmaceutical industry. With respect to each of these transactions, Goldman Sachs calculated the implied premium represented by the announced per share transaction price to the closing price of the target company’s common stock on the last trading day before the public announcement of the transaction (or the last undisturbed closing price for the target company’s common stock). The results of this analysis are listed below:

 

Date
Announced
  

Acquiror

  

Target

   Implied
Premium
 

03-30-2015

   Teva Pharmaceutical Industries Limited    Auspex Pharmaceuticals Inc.      42

03-05-2015

   AbbVie Inc.    Pharmacyclics Inc.      39

02-22-2015

   Valeant Pharmaceuticals International, Inc.    Salix Pharmaceuticals Ltd.      50

01-11-2015

   Shire plc    NPS Pharmaceuticals Inc.      51

12-08-2014

   Merck & Co., Inc.    Cubist Pharmaceuticals Inc.      37

12-02-2014

   Otsuka Holdings Co., Limited    Avanir Pharmaceuticals Inc.      13

10-09-2014

   Endo International plc    Auxilium Pharmaceuticals Inc.      55

08-24-2014

   Roche Holding AG    InterMune Inc.      63

06-09-2014

   Merck & Co., Inc.    Idenix Pharmaceuticals Inc.      239

04-07-2014

   Mallinckrodt plc    Questcor Pharmaceuticals Inc.      27

02-11-2014

   Mallinckrodt plc    Cadence Pharmaceuticals Inc.      26

12-19-2013

   Bayer AG    Algeta ASA      37

11-11-2013

   Shire plc    ViroPharma Inc.      64

11-07-2013

   Salix Pharmaceuticals, Limited    Santarus Inc.      36

08-25-2013

   Amgen Inc.    Onyx Pharmaceuticals Inc.      44

09-03-2012

   Valeant Pharmaceuticals International, Inc.    Medicis Pharmaceutical Corporation      39

07-16-2012

   GlaxoSmithKline plc    Human Genome Sciences Inc.      99

06-29-2012

   Bristol-Myers Squibb Company    Amylin Pharmaceuticals Inc.      101

01-25-2012

   Amgen Inc.    Micromet Inc.      33

01-07-2012

   Bristol-Myers Squibb Company    Inhibitex Inc.      163

05-02-2011

   Teva Pharmaceutical Industries Limited    Cephalon Inc.      39

09-17-2010

   Johnson & Johnson    Crucell NV      58

06-30-2010

   Celgene Corporation    Abraxis BioScience Inc.      43

05-16-2010

   Astellas Pharma Inc.    OSI Pharmaceuticals Inc.      55

High

           239

Mean

           61

Median

           43

Low

           13

Although none of the selected transactions is directly comparable to the transaction contemplated by the Transaction Agreement, the target companies in the selected transactions were companies with operations that, for the purposes of analysis, may be considered similar to certain of the Company’s results and product candidate profile, and as such, for purposes of analysis, the selected transactions may be considered similar to the transaction contemplated by the Transaction Agreement.

 

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Based on their review of the implied premia for the selected transactions and their professional judgment and experience, Goldman Sachs applied illustrative premia ranging from 44.0% to 101.0% to the closing price for Shares as of May 5, 2015 to derive illustrative values for the Shares ranging from $138.05 to $192.70. Goldman Sachs also calculated that the $225.92 implied price per Share referenced above represented a premium of 135.7% to the closing Share price on May 5, 2015.

General.

The preparation of a fairness opinion is a complex process and is not necessarily susceptible to partial analysis or summary description. Selecting portions of the analyses or of the summary set forth above, without considering the analyses as a whole, could create an incomplete view of the processes underlying the opinion of Goldman Sachs. In arriving at its fairness determinations, Goldman Sachs considered the results of all of the analyses and did not attribute any particular weight to any factor or analysis considered by it. Rather, Goldman Sachs made its determination as to fairness on the basis of its experience and professional judgment after considering the results of all of the analyses. No company or transaction used in the above analyses as a comparison is directly comparable to the Company or Alexion or the proposed transactions.

Goldman Sachs prepared these analyses for purposes of providing its opinion to the Company Board as to the fairness from a financial point of view to the holders of Shares, as of the date of its opinion, of the $115 in cash and 0.6581 shares of Alexion common stock to be paid to those holders pursuant to the Transaction Agreement. These analyses do not purport to be appraisals nor do they necessarily reflect the prices at which businesses or securities actually may be sold. Analyses based upon projections of future results are not necessarily indicative of actual future results, which may be significantly more or less favorable than suggested by these analyses. Because these analyses are inherently subject to uncertainty, being based upon numerous factors or events beyond the control of the parties or their respective advisors, none of the Company, Goldman Sachs or any other person assumes responsibility if future results are materially different from those forecast.

The consideration payable to holders of Shares was determined through arm’s-length negotiations between the Company and Alexion and was approved by the Company Board. Goldman Sachs provided advice to the Company during these negotiations. Goldman Sachs did not recommend any specific amount of consideration to the Company or that any specific amount of consideration constituted the only appropriate consideration for the proposed transactions.

As described above, Goldman Sachs’s opinion to the Company Board was one of many factors taken into consideration by the Company Board in making its determination to approve the Transaction Agreement. The foregoing summary does not purport to be a complete description of the analyses performed by Goldman Sachs in connection with the delivery of its fairness opinion to the Company Board and is qualified in its entirety by reference to its written opinion attached as Annex A to this Schedule 14D-9.

Goldman Sachs has advised the Company that Goldman Sachs and its affiliates are engaged in advisory, underwriting and financing, principal investing, sales and trading, research, investment management and other financial and non-financial activities and services for various persons and entities. Goldman Sachs has advised the Company that Goldman Sachs and its affiliates and employees, and funds or other entities they manage or in which they invest or have other economic interests or with which they co-invest, may at any time purchase, sell, hold or vote long or short positions and investments in securities, derivatives, loans, commodities, currencies, credit default swaps and other financial instruments of the Company, Alexion, any of their respective affiliates and third parties, including Baker Bros. Advisors LP, or “BB”), an affiliate of significant stockholders of the Company, and its affiliates and portfolio companies or any currency or commodity that may be involved in the transactions contemplated by the Transaction Agreement. Goldman Sachs has provided certain financial advisory and/or underwriting services to the Company and/or its affiliates from time to time for which Goldman Sachs’s Investment Banking Division has received, and may receive, compensation, including having acted as joint lead bookrunning manager with respect to the public offering of 3,450,000 Shares in January 2015 and the public offering of 2,300,000 Shares in March 2014 and as lead bookrunning manager with respect to the public offering

 

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of 3,162,500 Shares in September 2013. Goldman Sachs has advised the Company that Goldman Sachs also has provided certain financial advisory and/or underwriting services from time to time to companies in which funds advised by BB hold or have held equity interests for which Goldman Sachs’s Investment Banking Division has received, and may receive, compensation, including having acted as joint lead bookrunning manager in connection with the public offering of 23,000,000 shares of common stock of Idera Pharmaceuticals, Inc. in February 2015, as financial advisor to InterMune Inc. in connection with its sale in September 2014, as financial advisor to ViroPharma Incorporated in connection with its sale in January 2014, and as joint bookrunning manager in connection with the private placement of 0.375% convertible senior notes due 2018 (aggregate principal amount $375,000,000) and 1.25% convertible senior notes due 2020 (aggregate principal amount $375,000,000) of Incyte Corporation in November 2013. Goldman Sachs has advised the Company that Goldman Sachs may also in the future provide financial advisory and/or underwriting services to the Company and Alexion and their respective affiliates and to BB and companies in which funds advised by BB hold equity interest: for which Goldman Sachs’s Investment Banking Division may receive compensation. Goldman Sachs has advised the Company that affiliates of Goldman Sachs also may have co-invested with BB and funds advised by BB from time to time and may have invested in limited partnership units of funds advised by BB from time to time and may do so in the future. In addition, Goldman Sachs has advised the Company that a director of The Goldman Sachs Group is a director of Alexion.

The Company selected Goldman Sachs to serve as its financial advisor because it is an internationally recognized investment banking firm that has substantial experience in transactions similar to the transaction contemplated by the Transaction Agreement. Pursuant to a letter agreement, dated April 10, 2015, the Company engaged Goldman Sachs to act as its financial advisor in connection with a possible sale of the Company. The engagement letter between the Company and Goldman Sachs provides for a transaction fee determined based on the value as of closing of the Transaction Consideration to be paid to Company’s shareholders. Based on the closing price of the Alexion common stock as of May 19, 2015, the transaction fee, the principal portion of which is contingent upon consummation of the Transactions contemplated by the Transaction Agreement, is estimated to be approximately $48 million, of which $5 million was payable upon execution of the Transaction Agreement. In addition, the Company has agreed to reimburse Goldman Sachs for its expenses, including attorneys’ fees and disbursements, and to indemnify Goldman Sachs and related persons against certain liabilities that may arise out of its engagement.

 

Item 5. Person/Assets, Retained, Employed, Compensated or Used.

The Company retained Goldman Sachs to serve as its financial advisor in connection with the Offer and, in connection with such engagement, Goldman Sachs provided to the Company Board Goldman Sachs’s opinion described in “Item 4. The Solicitation or Recommendation—Opinions of the Financial Advisor to the Company Board,” which is filed as Annex A hereto and are incorporated herein by reference. The Company Board selected Goldman Sachs to serve as the Company’s financial advisor because it is an internationally recognized investment banking firm that has substantial experience in transactions similar to the Offer and Mergers, its reputation in the investment community and its familiarity with the Company and its business.

In connection with Goldman Sachs’s services as the Company’s financial advisor, the Company has agreed to pay Goldman Sachs a transaction fee determined based on the value as of closing of the consideration to be paid to the Company’s stockholders. Based on the closing price of the Alexion common stock as of May 19, 2015, the transaction fee, the principal portion of which is contingent upon consummation of the transaction contemplated by the Transaction Agreement, is estimated to be approximately $48 million, of which $5 million was payable upon execution of the Transaction Agreement. In addition, the Company has agreed to reimburse Goldman Sachs for its expenses, including fees and expenses of counsel, and to indemnify Goldman Sachs and related parties against liabilities, including liabilities under federal securities laws, arising from Goldman Sachs’s engagement.

Except as set forth above, neither the Company nor any person acting on its behalf has or currently intends to employ, retain or compensate any person to make solicitations or recommendations to the stockholders of the Company on its behalf with respect to the Offer.

 

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Item 6. Interest in Securities of the Subject Company.

Other than in the ordinary course of business in connection with the Company’s employee benefit plans, no transactions in the Shares have been effected during the 60 days prior to June 20, 2015, by the Company, or, to the best of the Company’s knowledge, by any of the Company’s directors, executive officers or affiliates or subsidiaries of the Company, other than:

 

Name    Date    No.
Shares
  

Sale or

Exercise

Price as

Applicable

   Nature of Transaction
Anthony Quinn    04/06/2015    10,000    $0.95    Shares acquired pursuant to exercise of stock options
Anthony Quinn    04/06/2015    9,503    $23.00    Shares acquired pursuant to exercise of stock options
Anthony Quinn    04/06/2015    29,503    $93.76    Sale effected pursuant to Rule 10b5-1 plan
Glen Williams    04/07/2015    2,769    $40.32    Shares acquired pursuant to exercise of stock options
Glen Williams    04/07/2015    2,769    $96.04    Sale effected pursuant to Rule 10b5-1 plan
Glen Williams    04/08/2015    15,263    $40.32    Shares acquired pursuant to exercise of stock options
Glen Williams    04/08/2015    24,600    $57.56    Shares acquired pursuant to exercise of stock options
Glen Williams    04/08/2015    39,863    $96.08    Sale effected pursuant to Rule 10b5-1 plan
Anthony Quinn    04/15/2015    10,000    $40.74    Shares acquired pursuant to exercise of stock options
Anthony Quinn    04/15/2015    10,000    $105.00    Sale effected pursuant to Rule 10b5-1 plan
Anthony Quinn    04/21/2015    10,000    $108.00    Sale effected pursuant to Rule 10b5-1 plan
Anthony Quinn    04/27/2015    10,000    $1.70    Shares acquired pursuant to exercise of stock options
Anthony Quinn    04/27/2015    10,000    $110.00    Sale effected pursuant to Rule 10b5-1 plan
Glen Williams    05/06/2015    833    $40.32    Shares acquired pursuant to exercise of stock options
Gen Williams    05/06/2015    833    $57.56    Shares acquired pursuant to exercise of stock options
Glen Williams    05/06/2015    666    $203.99    Sale effected pursuant to Rule 10b5-1 plan
Glen Williams    05/06/2015    400    $204.94    Sale effected pursuant to Rule 10b5-1 plan
Glen Williams    05/06/2015    400    $206.27    Sale effected pursuant to Rule 10b5-1 plan
Glen Williams    05/06/2015    100    $206.97    Sale effected pursuant to Rule 10b5-1 plan
Glen Williams    05/06/2015    100    $$215.26    Sale effected pursuant to Rule 10b5-1 plan

 

Item 7. Purposes of the Transaction and Plans or Proposals.

Except as indicated in Items 2, 3 and 4 of this Schedule 14D-9, (a) the Company is not undertaking or engaged in any negotiations in response to the Offer that relate to, or would result in: (i) a tender offer for or other acquisition of the Shares by the Company, any of its subsidiaries, or any other person; (ii) any extraordinary transaction such as a merger, reorganization or liquidation, involving the Company or any of its subsidiaries; (iii) any purchase, sale or transfer of a material amount of assets of the Company or any of its subsidiaries; or (iv) any material change in the present dividend rates or policy, or indebtedness or capitalization of the Company and (b) there are no transactions, resolutions of the Company Board or agreements in principle or signed contracts in response to the Offer that relate to, or would result in, one or more of the events referred to in clause (a) of this Item 7.

 

Item 8. Additional Information.

(a) Golden Parachute Compensation.

The information set forth below is intended to comply with Item 402(t) of Regulation S-K, which requires disclosure regarding the compensation for the Company’s named executive officers that is based on or otherwise relates to the Mergers. This compensation is referred to as “golden parachute” compensation by the applicable SEC disclosure rules, and in this section we use such term to describe the Merger-related compensation payable to the Company’s named executive officers.

 

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As described above under the heading “— Employment Agreements and Severance Payments,” pursuant to the terms of their employment agreements, each named executive officer is entitled to certain “double-trigger” severance payments upon a qualifying termination of employment. In the case of Mr. Patel, such severance payments are triggered upon (x) Mr. Patel’s termination by the Company without “cause” or (y) Mr. Patel’s resignation from the Company for “good reason,” in each case, within 12 months following the Effective Time. In the case of the other named executive officers, such severance payments are triggered upon a termination without “cause” within 12 months following the Effective Time.

As described above under the heading “— Treatment of Shares, Stock Options and Restricted Stock Units In Connection with the Offer and Mergers,” pursuant to the terms of the Transaction Agreement, (x) the vesting of each Stock Option and RSU (other than the Rolled 2015 RSUs Award) is being accelerated, such that all such awards are “single-trigger” and will become fully vested and be settled in an amount in cash and shares of Alexion common stock immediately prior to the Effective Time and (y) the vesting of each Rolled 2015 RSUs Award is not being accelerated, such that, in accordance with the terms of such awards, all such awards are “double-trigger” and will be converted into a restricted stock unit award in respect of Alexion common stock subject to the same terms and conditions as were applicable to the related Rolled 2015 RSU Award immediately prior to the Effective Time (including accelerated vesting upon a termination without “cause” or resignation for “good reason” within two years following the Effective Time). Each of the named executive officers are expected to receive a 2015 grant of RSUs prior to the Effective Date, but, as of the date of this Schedule 14D-9, no grants have been made. Pursuant to the Transaction Agreement, one half of such RSUs award will be a “double-trigger” Rolled 2015 RSUs Award that will be converted into a restricted stock unit award in respect of Alexion common stock and the other half will “single-trigger” and will become fully vested and be settled in an amount in cash and shares of Alexion common stock immediately prior to the Effective Time.

The amounts set forth in the table below assume the following:

 

    the Effective Time occurred on May 21, 2015, the last practicable date prior to the filing of this Schedule 14D-9;

 

    the named executive officers were terminated without “cause” immediately following the Effective Time on May 21, 2015;

 

    for purposes of valuing the Stock Options and RSUs, a price per share of Alexion common stock of $161.50, which is the average closing price of a share of Alexion common stock on the Nasdaq Global Select Market over the first five business days following May 6, 2015 (the date on which the execution of the Transaction Agreement was first publicly announced); and

 

    that the amounts set forth in the table below are as calculated before any taxes that may be due on such amounts.

In addition, the amounts reported below are estimates based on multiple assumptions that may or may not actually occur, including assumptions described in this Schedule 14D-9. As a result, the actual amounts, if any, to be received by a named executive officer may materially differ from the amounts set forth below.

 

Executive    Cash
Severance
Payment
($)(1)
     Value of
Equity ($)(2)
     Total ($)  

Sanj K. Patel

   $ 2,299,361         42,663,742         44,963,103   

Carsten Boess

   $ 542,828         13,152,455         13,695,283   

Robert Bazemore

   $ 716,500         14,666,831         15,383,331   

Anthony G. Quinn

   $ 665,543         14,814,609         15,480,152   

Glenn Williams

   $ 483,751         12,631,495         13,115,246   

 

(1)

These amounts represent “double-trigger” cash severance amounts payable in a lump sum following a qualifying termination of employment without “cause” or, in the case of Mr. Patel only, for “good reason”

 

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  within 12 months following the Effective Time, in each case, assuming base salaries and bonus opportunities remain unchanged from their current levels. The estimated amounts for each named executive officer are as follows:

 

    Mr. Patel: a severance payment of $2,299,361 (which is equal to the sum of (x) 2 times Mr. Patel’s annual salary plus target bonus in 2015, (y) a pro-rata share of his target annual cash bonus for 2015 and (z) a one-time bonus of $25,000);

 

    Mr. Boess: a severance payment of $542,828 (which is equal to the sum of (x) Mr. Boess’ annual salary plus target bonus in 2015, and (y) a one-time bonus of $16,500);

 

    Mr. Bazemore: a severance payment of $716,500 (which is equal to the sum of (x) Mr. Bazemore’s annual salary plus target bonus in 2015, and (y) a one-time bonus of $16,500);

 

    Dr. Quinn: a severance payment of $665,543 (which is equal to the sum of (x) Mr. Quinn’s annual salary plus target bonus in 2015, and (y) a one-time bonus of $16,500); and

 

    Mr. Williams: a severance payment of $483,751 (which is equal to the sum of (x) Mr. Williams’ annual salary plus target bonus in 2015, and (y) a one-time bonus of $16,500).

 

(2) These amounts represent the value of the unvested Stock Options held by each named executive officer and RSUs held by Mr. Bazemore, in each case, the vesting of which is being accelerated immediately prior to the Effective Time as agreed by Offeror under the Transaction Agreement (and, as such, becomes “single-trigger”). The amounts in this column are comprised of the value of each named executive officer’s “single-trigger” unvested stock options and “single-trigger” RSUs, as shown below. The value of such awards is based on the cash consideration to be received in respect of the unvested “single-trigger” Stock Options and RSUs and the aggregate value of Alexion common stock to be received in respect of the “single-trigger” Stock Options and RSUs based on a price per share of Alexion common stock of $161.50, which is the average closing price of a share of Alexion common stock on the Nasdaq Global Select Market over the first five business days following May 6, 2015 (the date on which the execution of the Transaction Agreement was first publicly announced). While none of the named executive officers other than Mr. Bazemore held any RSUs as of May 21, 2015, as discussed under “—Consideration for Restricted Stock Units” above, the Company’s executive officers are expected to receive grants of RSUs between the signing of the Transaction Agreement and the Effective Date. However, as of the date of this Schedule 14D-9, no such grants have been made. Accordingly, they are not reflected here.

 

Name

   Aggregate Value of
“in-the-money”  Single-
Trigger Stock
Options that would Vest
($)
     Aggregate Value of
Single-Trigger RSU
Awards that would  Vest
($)
     Total
($)
 

Sanj K. Patel

     42,663,742         —           42,663,742   

Carsten Boess

     13,152,455         —           13,152,455   

Robert Bazemore

     8,028,297         6,638,534         14,666,831   

Anthony G. Quinn

     14,814,609         —           14,814,609   

Glenn Williams

     12,631,495         —           12,631,495   

(b) Appraisal Rights.

No appraisal rights are available in connection with the Offer. However, if the Offer is successful and the First Merger is consummated, stockholders of the Company who have not properly tendered in the Offer, and who otherwise comply with the applicable procedures for demanding appraisal under DGCL Section 262, will be entitled to seek appraisal for the “fair value” of their Shares as determined by the Delaware Court of Chancery.

 

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Stockholders should be aware that a financial advisor’s opinion as to the fairness, from a financial point of view, of the consideration payable in a sale transaction, such as the Offer or the Mergers, is not an opinion as to, and does not otherwise address, fair value under DGCL Section 262. Any stockholder contemplating the exercise of such appraisal rights should review carefully the provisions of DGCL Section 262, particularly the procedural steps required to perfect such rights.

Under DGCL Section 262, where a merger is approved under DGCL Section 251(h), either a constituent corporation before the effective date of the merger, or the surviving corporation within 10 days thereafter, shall notify each of the holders of any class or series of stock of such constituent corporation who are entitled to appraisal rights of the approval of the merger or consolidation and that appraisal rights are available for any or all shares of such class or series of stock of such constituent corporation, and shall include in such notice a copy of Section 262. THIS SCHEDULE 14D-9 CONSTITUTES THE FORMAL NOTICE OF APPRAISAL RIGHTS UNDER DGCL SECTION 262. FAILURE TO FOLLOW THE STEPS REQUIRED BY DGCL SECTION 262 FOR PERFECTING APPRAISAL RIGHTS WILL RESULT IN THE LOSS OF SUCH RIGHTS. The foregoing summary of appraisal rights under DGCL is not complete and is qualified in its entirety by the full text of DGCL Section 262, which is attached to this Schedule 14D-9 as Annex B.

Stockholders wishing to exercise the right to seek an appraisal of their Shares must do ALL of the following:

 

    the stockholder must deliver to the Company a written demand for appraisal by the later of the consummation of the Offer and 20 days after the date of mailing of this Schedule 14D-9 (which date of mailing is May 22, 2015);

 

    the stockholder must not tender his, her or its Shares pursuant to the Offer; and

 

    the stockholder must continuously hold the Shares from the date of making the demand through the Effective Time.

Only a holder of record of Shares issued and outstanding immediately prior to the Effective Time may assert appraisal rights for the Shares registered in that holder’s name. A demand for appraisal must be executed by or on behalf of the stockholder of record. The demand should set forth, fully and correctly, the record stockholder’s name as it appears on the stock certificates. The demand must reasonably inform the identity of the stockholder and state that the stockholder intends to demand appraisal of his, her or its Shares.

If the Shares are owned of record in a fiduciary capacity, such as by a trustee, guardian or custodian, execution of the demand must be made in that capacity, and if the Shares are owned of record by more than one person, as in a joint tenancy and tenancy in common, the demand must be executed by or on behalf of all joint owners. An authorized agent, including two or more joint owners, may execute a demand for appraisal on behalf of a holder of record; however, the agent must identify the record owner or owners and expressly disclose the fact that, in executing the demand, the agent is agent for such owner or owners. A record holder, such as a broker who holds Shares as nominee for several beneficial owners, may exercise appraisal rights with respect to the Shares issued and outstanding immediately prior to the Effective Time held for one or more beneficial owners while not exercising such rights with respect to the Shares held for other beneficial owners; in such case, however, the written demand should set forth the number of Shares issued and outstanding immediately prior to the Effective Time as to which appraisal is sought and where no number of Shares is expressly mentioned the demand will be presumed to cover all Shares which are held in the name of the record owner. STOCKHOLDERS WHO HOLD THEIR SHARES IN BROKERAGE ACCOUNTS OR OTHER NOMINEE FORMS, AND WHO WISH TO EXERCISE APPRAISAL RIGHTS, SHOULD CONSULT WITH THEIR BROKERS TO DETERMINE THE APPROPRIATE PROCEDURES FOR THE NOMINEE HOLDER TO MAKE A DEMAND FOR APPRAISAL OF THOSE SHARES. A PERSON HAVING A BENEFICIAL INTEREST IN SHARES HELD OF RECORD IN THE NAME OF ANOTHER PERSON, SUCH AS A BROKER OR NOMINEE, MUST ACT PROMPTLY TO CAUSE THE RECORD HOLDER TO FOLLOW PROPERLY AND IN A TIMELY MANNER THE STEPS NECESSARY TO PERFECT APPRAISAL RIGHTS. IF A STOCKHOLDER HOLDS HIS, HER OR ITS

 

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SHARES THROUGH A BROKER WHO IN TURN HOLDS THE STOCKHOLDER’S SHARES THROUGH A CENTRAL SECURITIES DEPOSITORY NOMINEE SUCH AS CEDE & CO., A DEMAND FOR APPRAISAL OF SUCH SHARES MUST BE MADE BY OR ON BEHALF OF THE DEPOSITORY NOMINEE AND MUST IDENTIFY THE DEPOSITORY NOMINEE AS RECORD HOLDER.

A stockholder who elects to exercise appraisal rights under DGCL Section 262 should mail or deliver a written demand to:

Synageva BioPharma Corp.

33 Hayden Avenue

Lexington, Massachusetts 02421

Attn: Secretary

If the First Merger is consummated pursuant to DGCL Section 251(h), within 10 days after the Effective Date, the First Surviving Corporation or the Surviving Company must send an additional notice of the Effective Date to all of our stockholders who are entitled to appraisal rights and who have delivered a written demand for appraisal to us in accordance with DGCL Section 262. Within 120 days after the Effective Time, either the First Surviving Corporation, the Surviving Company or any stockholder who has complied with the requirements of DGCL Section 262 and who is otherwise entitled to appraisal rights may file a petition in the Delaware Court of Chancery, with a copy served upon the First Surviving Corporation and the Surviving Company in the case of a petition filed by a stockholder, demanding a determination of the fair value of the Shares held by all dissenting stockholders. A person who is the beneficial owner of Shares held in a voting trust or by a nominee on behalf of such person may, in such person’s own name, file the petition described in the previous sentence. The First Surviving Corporation and the Surviving Company are under no obligation to file any such petition and have no intention of doing so. If a petition for appraisal is not timely filed, all stockholders’ appraisal rights will cease.

Stockholders who desire to have their Shares appraised should initiate any petitions necessary for the perfection of their appraisal rights within the time periods and in the manner prescribed in DGCL Section 262.

Within 120 days after the Effective Time, any stockholder who has complied with the provisions of DGCL Section 262 to that point in time may receive from the First Surviving Corporation or the Surviving Company, upon written request, a statement setting forth the aggregate number of Shares not tendered into the Offer and with respect to which the First Surviving Corporation or the Surviving Company has received demands for appraisal, and the aggregate number of holders of those Shares. A person who is the beneficial owner of Shares held in a voting trust or by a nominee on behalf of such person may, in such person’s own name, request from the First Surviving Corporation or the Surviving Company the statement described in the previous sentence. The First Surviving Corporation or the Surviving Company must mail this statement to the stockholder within the later of 10 days of receipt of the request or 10 days after expiration of the period for delivery of demands for appraisal.

If a petition for appraisal is duly filed by a stockholder and a copy of the petition is delivered to the First Surviving Corporation or the Surviving Company, the First Surviving Corporation or the Surviving Company will then be obligated, within 20 days after receiving service of a copy of the petition, to file in the office of the Register in Chancery a duly verified list containing the names and addresses of all stockholders who have demanded an appraisal of their Shares and with whom agreements as to the value of their Shares have not been reached by the First Surviving Corporation or the Surviving Company. After notice to stockholders who demanded appraisal of their Shares as may be required by the Delaware Court of Chancery, the Delaware Court of Chancery will conduct a hearing upon the petition to determine those stockholders who have complied with DGCL Section 262 and who have become entitled to the appraisal rights provided thereby.

The Delaware Court of Chancery may require the stockholders demanding appraisal who hold certificated Shares to submit their stock certificates to the court for notation of the pendency of the appraisal proceedings. If any stockholder fails to comply with the court’s direction, the court may dismiss the proceeding as to the stockholder.

 

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The Delaware Court of Chancery will thereafter determine the fair value of the Shares held by stockholders who have complied with DGCL Section 262, exclusive of any element of value arising from the accomplishment or expectation of the Mergers, but together with the interest if any, to be paid on the amount determined to be fair value. Such interest rate shall accrue from the Effective Date through the date of payment of the judgment, compounded quarterly and shall accrue at 5% over the Federal Reserve discount rate (including any surcharge), unless the Delaware Court of Chancery in its discretion determines otherwise for good cause shown.

In determining the fair value, the Delaware Court of Chancery will take into account all relevant factors. In Weinberger v. UOP, Inc., the Delaware Supreme Court discussed the factors that could be considered in determining fair value in an appraisal proceeding, stating that “proof of value by any techniques or methods which are generally considered acceptable in the financial community and otherwise admissible in court” should be considered and that “[f]air price obviously requires consideration of all relevant factors involving the value of a company.” The Delaware Supreme Court has stated that in making this determination of fair value the court must consider market value, asset value, dividends, earnings prospects, the nature of the enterprise and any other facts which could be ascertained as of the date of the merger which throw any light on future prospects of the merged corporation. DGCL Section 262 provides that fair value is to be “exclusive of any element of value arising from the accomplishment or expectation of the merger.” In Cede & Co. v. Technicolor, Inc., the Delaware Supreme Court stated that such exclusion is a “narrow exclusion [that] does not encompass known elements of value,” but which rather applies only to the speculative elements of value arising from such accomplishment or expectation. In Weinberger, the Delaware Supreme Court construed DGCL Section 262 to mean that “elements of future value, including the nature of the enterprise, which are known or susceptible of proof as of the date of the merger and not the product of speculation, may be considered.” The Delaware Court of Chancery may determine the fair value of the Shares to be more than, less than or equal to the consideration that the stockholders would otherwise receive under the Transaction Agreement, which is the same as the Transaction Consideration. If no party files a petition for appraisal in a timely manner, then stockholders will lose the right to an appraisal, and will instead receive the Transaction Consideration described in the Transaction Agreement.

The Delaware Court of Chancery may determine the costs of the appraisal proceeding (which do not include attorneys’ fees or the fees and expenses of experts) and those costs may be taxed upon the parties as the Delaware Court of Chancery determines to be equitable under the circumstances. Upon application of a stockholder, the Delaware Court of Chancery may order all or a portion of the expenses incurred by any stockholder in connection with the appraisal proceeding, including reasonable attorneys’ fees and the fees and expenses of experts, to be charged pro rata against the value of all Shares entitled to appraisal.

The fair value of the Shares as determined under DGCL Section 262 could be greater than, the same as, or less than the Transaction described in the Transaction Agreement. An opinion of an investment banking firm as to the fairness, from a financial point of view, of the consideration payable in a merger is not an opinion as to, and does not in any manner address, fair value under DGCL Section 262. No representation is made as to the outcome of the appraisal of fair value as determined by the Delaware Court of Chancery and stockholders should recognize that such an appraisal could result in a determination of a value higher or lower than, or the same as, the Transaction Consideration.

Any stockholder who has duly demanded an appraisal in compliance with DGCL Section 262 may not, after the Effective Time, vote the Shares subject to the demand for any purpose or receive any dividends or other distributions on those Shares, except dividends or other distributions payable to holders of record of Shares as of a record date prior to the Effective Time.

If no petition for appraisal is filed within 120 days after the Effective Time, or if a stockholder who has not commenced an appraisal proceeding or joined that proceeding as a named party delivers a written withdrawal of the stockholder’s demand for appraisal and an acceptance of the terms offered in the First Merger within 60 days after the Effective Time, then the right of the stockholder to appraisal will cease. Any attempt to withdraw made more than 60 days after the Effective Time will require our written approval, and no appraisal proceeding in the Delaware Court of Chancery will be dismissed as to any stockholder without the approval of the Delaware Court

 

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of Chancery, and may be conditioned on such terms as the Delaware Court of Chancery deems just; provided, however, that any stockholder who has not commenced an appraisal proceeding or joined that proceeding as a named party may withdraw his, her or its demand for appraisal and accept the Transaction Consideration offered pursuant to the Transaction Agreement within 60 days after the Effective Time. If the stockholder fails to perfect, successfully withdraws or loses the appraisal right, the stockholder’s Shares will be converted into the right to receive the Transaction Consideration described in the Transaction Agreement.

FAILURE TO FOLLOW THE STEPS REQUIRED BY DGCL SECTION 262 FOR PERFECTING APPRAISAL RIGHTS MAY RESULT IN THE LOSS OF APPRAISAL RIGHTS. IN THAT EVENT, YOU WILL BE ENTITLED TO RECEIVE THE TRANSACTION CONSIDERATION DESCRIBED IN THE TRANSACTION AGREEMENT FOR YOUR SHARES IN ACCORDANCE WITH THE TRANSACTION AGREEMENT. IN VIEW OF THE COMPLEXITY OF THE PROVISIONS OF DGCL SECTION 262, IF YOU ARE A HOLDER OF SHARES AND ARE CONSIDERING EXERCISING YOUR APPRAISAL RIGHTS UNDER THE DGCL, YOU SHOULD CONSULT YOUR OWN LEGAL ADVISOR.

(c) Anti-Takeover Statute.

As a Delaware corporation, the Company is subject to Section 203 of the DGCL (“Section 203”). In general, Section 203 would prevent an “interested stockholder” (generally defined as a person beneficially owning 15% or more of a corporation’s voting stock) from engaging in a “business combination” (as defined in Section 203) with a Delaware corporation for three years following the date such person became an interested stockholder unless: (i) before such person became an interested stockholder, the board of directors of the corporation approved either the business combination or the transaction which resulted in the interested stockholder becoming an interested stockholder, (ii) upon consummation of the transaction which resulted in the interested stockholder becoming an interested stockholder, such interested stockholder owned at least 85% of the voting stock of the corporation outstanding at the time the transaction commenced (excluding for purposes of determining the number of shares of outstanding shares owned by directors who are also officers and by employee stock plans that do not allow plan participants to determine confidentially whether to tender shares), or (iii) following the transaction in which such person became an interested stockholder, the business combination is (x) approved by the board of directors of the corporation and (y) authorized at a meeting of stockholders by the affirmative vote of the holders of at least 66 2/3% of the outstanding voting stock of the corporation not owned by the interested stockholder. In accordance with the provisions of Section 203, the Company Board has approved the Transaction Agreement and the transactions contemplated thereby, as described in Item 4 above and, therefore, the restrictions of Section 203 are inapplicable to the Offer and the First Merger and the transactions contemplated under the Transaction Agreement.

(d) Regulatory Approvals.

Antitrust in the United States

Under the provisions of the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended (the “HSR Act”), and related rules and regulations issued by the Federal Trade Commission (the “FTC”), applicable to the Offer, the acquisition of Shares pursuant to the Offer may be consummated following the expiration of a 30-day waiting period following the filing by Alexion of its Premerger Notification and Report Form with respect to the Offer, unless (a) the parties receive a request for additional information or documentary material (a “Second Request”) from the Antitrust Division of the U.S. Department of Justice (the “Antitrust Division”) or the FTC, or (b) early termination of the waiting period is granted. If, within the initial 30-day waiting period, either the Antitrust Division or the FTC issues a Second Request concerning the Offer, the waiting period will be extended for an additional 30-day period following the date of the parties’ substantial compliance with the Second Request. Complying with a Second Request may take a significant amount of time.

Alexion filed its Premerger Notification and Report Form with respect to the Offer with the Antitrust Division and with the FTC on May 15, 2015. Assuming the filing is accepted as complete, the initial 30-day

 

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waiting period will expire on June 15, 2015, unless otherwise early terminated or extended. The Company filed its Premerger Notification and Report Form with respect to the Offer with the Antitrust Division on May 15, 2015 and with the FTC on May 18, 2015.

At any time before or after Alexion’s acquisition of Shares pursuant to the Offer, the Antitrust Division or the FTC could take such action under the antitrust laws as either deems necessary or desirable in the public interest, including seeking to enjoin the purchase of the Shares pursuant to the Offer or seeking the divestiture of Shares acquired by Alexion or the divestiture of substantial assets of the Company or its subsidiaries or Alexion or its subsidiaries. State attorneys general may also bring legal action under state antitrust and consumer protection laws. Private parties may also bring legal action under federal and state antitrust and consumer protection laws under certain circumstances. There can be no assurance that a challenge to the Offer on antitrust grounds will not be made or, if such a challenge is made, the result thereof.

Alexion and the Company conduct business in a number of foreign countries. In connection with the purchase of the Shares pursuant to the Offer, the laws of certain of these foreign countries may require the filing of information with, or the obtaining of the approval of, governmental authorities therein.

(e) Merger without a Vote.

If the Offer is consummated, the Company will not seek the approval of the Company’s remaining public stockholders before effecting the First Merger. Section 251(h) of the DGCL provides that following consummation of a successful tender offer for a corporation (the shares of which are listed on a national securities exchange or held of record by more than 2,000 holders), and subject to certain statutory provisions, if the acquirer holds at least the number of shares of each class or series of stock of the target corporation that would otherwise be required to approve a merger for the target corporation, and the other stockholders receive the same consideration for their stock in the merger as was payable in the tender offer, the acquirer can effect a merger without the action of the other stockholders of the target corporation. Accordingly, if Alexion consummates the Offer, Alexion and the Company are obligated pursuant to the Transaction Agreement to effect the First Merger without a vote of the stockholders of the Company in accordance with Section 251(h) of the DGCL.

(f) Certain Company Management Projections.

Other than full-year financial guidance provided to investors, which may cover such areas as projected operating expenses and projected net loss, among other items, and which it may update from time to time during the relevant year, the Company does not, as a matter of course, publicly disclose long-term forecasts or internal projections as to future revenues, earnings or other results, due to, among other reasons, the unpredictability of the underlying assumptions and estimates.

In connection with its evaluation of Alexion’s acquisition proposal, the Company’s management prepared certain unaudited prospective financial information, based on the latest available long-range plans of the Company, that was presented to the Company Board in May 2015. These financial projections were adjusted for the probability of success of the Company’s portfolio.

The Company’s management provided the financial projections (i) to the Company Board in May 2015 for purposes of considering and evaluating Alexion’s acquisition proposal and (ii) to Goldman Sachs in connection with the rendering of Goldman Sachs’s fairness opinion to the Company Board and in performing its related financial analyses, as described above in “Opinions of the Financial Advisor to the Company Board—Opinion of Goldman Sachs”. For internal operating and planning purposes, the Company does not ordinarily forecast beyond 2025; however, for the purposes referred to in the preceding sentence, the Company elected to prepare financial projections covering periods beyond 2025. The Company Board directed Goldman Sachs to use the financial projections in performing its financial analyses in connection with the rendering of its fairness opinion.

 

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To give our stockholders access to certain nonpublic information that was available to the Company Board at the time of the evaluation of the Offer, the Mergers and the other transactions contemplated by the Transaction Agreement, we have included the financial projections below.

The financial projections were not provided to Alexion until after the execution of the Transaction Agreement.

The financial projections were prepared by the Company’s management based on assumptions they believed to be potentially achievable. The financial projections reflected numerous assumptions about the Company’s potential products, including but not limited to probability-weighed projections adjusted to account for the potential of (i) the Company achieving approval of Kanuma™ in LAL Deficiency, Atherosclerosis and Nonalcoholic Steatohepatitis (or NASH), (ii) SBC-103 achieving approval as an IV-only administration for MPS IIIB and (iii) SBC-105 achieving approval in at least one indication. The probability-weighted projections also assumed that the Company would develop new products utilizing the Company’s manufacturing platform, including both novel rare disease therapeutics as well as bio-superior therapeutics for known rare diseases. The financial projections assume lower probability of success for approval of certain of the Company’s products in certain indications and for those that have a longer development pathway and timeline, which resulted in less favorable prospective financial returns for those indications and products. The financial projections include estimated revenue in 2023-2025 from currently unidentified products equal to $38 million in 2023, $95 million in 2024 and $173 million in 2025. The financial projections also assumed market exclusivity for Kanuma through 2031 and cost of good margins ranging from 10-13% for Kanuma, 15% for SBC-103 and the platform and 18% for SBC-105.

The financial projections are summarized below:

 

    2015     2016     2017     2018     2019     2020     2021     2022     2023     2024     2025     2026     2027     2028     2029     2030  

Total Sales

  $ 11      $ 87      $ 302      $ 540      $ 754      $ 962      $ 1,212      $ 1,422      $ 1,873      $ 2,465      $ 3,075      $ 3,715      $ 4,390      $ 4,989      $ 5,573      $ 5,945   

EBIT

  $ (288   $ (222   $ (58   $ 133      $ 323      $ 387      $ 546      $ 675      $ 909      $ 1,136      $ 1,372      $ 1,615      $ 1,870      $ 2,101      $ 2,321      $ 2,480   

Free Cash Flow

    (299     (289     (142     72        263        336        478        600        741        856        1,054        1,259        1,472        1,678        1,867        2,054   

In connection with the financial projections, the Company’s management also prepared product-level probability adjusted forecasts of sales, a summary of which is set forth below.

 

    2015     2016     2017     2018     2019     2020     2021     2022     2023     2024     2025     2026     2027     2028     2029     2030  

Kanuma for LAL-Deficiency

  $ 7      $ 84      $ 300      $ 539      $ 753      $ 947      $ 1,140      $ 1,274      $ 1,352      $ 1,417      $ 1,468      $ 1,511      $ 1,555      $ 1,601      $ 1,649      $ 1,697   

Kanuma (for other indications)

    0        0        0        0        0        0        0        0        44        93        155        225        308        328        333        337   

SBC-103

    0        0        0        0        0        16        72        148        213        273        332        392        448        490        510        518   

SBC-105

    0        0        0        0        0        0        0        0        226        587        949        1,310        1,671        2,033        2,394        2,530   

Total Product Revenue

  $ 7      $ 84      $ 300      $ 539      $ 753      $ 962      $ 1,212      $ 1,422      $ 1,835      $ 2,371      $ 2,902      $ 3,438      $ 3,982      $ 4,452      $ 4,886      $ 5,082   

Platform Revenue

    0        0        0        0        0        0        0        0        38        95        173        276        409        537        687        863   

Other Revenue

    4        3        2        1        1        0        0        0        0        0        0        0        0        0        0        0   

Total Sales

  $ 11      $ 87      $ 302      $ 540      $ 754      $ 962      $ 1,212      $ 1,422      $ 1,873      $ 2,465      $ 3,075      $ 3,715      $ 4,390      $ 4,989      $ 5,573      $ 5,945   

 

 

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The financial projections were developed from historical financial statements and a series of independent assumptions and estimates of Company management related to future trends and did not give effect to any significant changes or expenses as a result of the Offer, the Mergers or the other transactions contemplated by the Transaction Agreement or any other effects of the Offer, the Mergers and the other transactions contemplated by the Transaction Agreement. The financial projections have been prepared by Company management and are the responsibility of Company management. The financial projections were not prepared with a view toward public disclosure; and, accordingly, do not necessarily comply with published guidelines of the SEC, the guidelines established by the American Institute of Certified Public Accountants for preparation and presentation of financial forecasts, or GAAP. PricewaterhouseCoopers LLP, the Company’s independent registered public accounting firm, has not audited, reviewed, compiled or performed any procedures with respect to the financial projections and does not express an opinion or any form of assurance related thereto.

The financial projections, while presented with numerical specificity, necessarily were based on numerous variables and assumptions that are inherently uncertain and many of which are beyond the control of Company management. Because the financial projections cover multiple years, by their nature, they become subject to greater uncertainty with each successive year. The assumptions upon which the financial projections were based necessarily involve judgments with respect to, among other things, future economic, competitive and regulatory conditions and financial market conditions, all of which are difficult or impossible to predict accurately and many of which are beyond the Company’s control. The financial projections also reflect assumptions as to certain business decisions that are subject to change. Important factors that may affect actual results and result in the financial projections not being achieved include, but are not limited to, success of preclinical and clinical testing, the impact of regulatory decisions by regulatory agencies, the timing of regulatory approvals and introduction of new products, market acceptance of new products, availability of third-party reimbursement, impact of competitive products and pricing, the effect of regulatory actions, the impact of legal proceedings, the effect of global economic conditions, the cost and effect of changes in tax and other legislation and other risk factors described in the Company’s quarterly report on Form 10-Q for the quarter ended March 31, 2015. In addition, the financial projections may be affected by the Company’s ability to achieve strategic goals, objectives and targets over the applicable period.

In light of the foregoing factors and the uncertainties inherent in the financial projections, Company stockholders are cautioned not to place undue reliance on the financial projections and they should be evaluated in conjunction with the Company’s historical financial statements and other information regarding the Company and its public filings with the SEC. The financial projections speak only as of the date they were prepared and have not been updated except as described therein. As a result, they do not reflect subsequent events such as the announcement and pendency of the transaction with Alexion.

(g) Cautionary Note Regarding Forward-Looking Statements.

This Schedule 14D-9 contains forward-looking statements that are not historical facts. The Company has identified some of these forward-looking statements with words like “believe,” “may,” “could,” “would,” “might,” “possible,” “potential,” “will,” “should,” “expect,” “intend,” “plan,” “anticipate,” “estimate,” “approximate” or “continue,” or the negative of these words, other terms of similar meaning or the use of future dates. Forward-looking statements may include, without limitation, statements regarding prospective performance and opportunities and the outlook of our business; statements regarding the anticipated timing of filings and approvals relating to the transaction; statements regarding the expected timing of the completion of the transaction; statements regarding the ability to complete the transaction considering the various closing conditions; the Forecasts, including revenue and cost projections and Synergies; statements of expectation or belief; and any statements regarding assumptions underlying any of the foregoing. Investors are cautioned not to place undue reliance on these forward-looking statements. Actual results could differ materially from those currently anticipated due to a number of risks and uncertainties. Risks and uncertainties that could cause results to differ from expectations include: uncertainties as to the timing of the Offer and Mergers; uncertainties as to how many Shares will be tendered in the Offer; the possibility that competing offers will be made; the possibility

 

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that various closing conditions for the transaction may not be satisfied or waived, including that a governmental entity may prohibit, delay or refuse to grant approval for the consummation of the transaction; the effects of disruption from the transaction making it more difficult to maintain relationships with employees, customers, vendors and other business partners; the risk that stockholder litigation may be commenced in connection with the Offer and may result in significant costs of defense, indemnification and liability; other business effects, including the effects of industry, economic or political conditions outside of the Company’s control; transaction costs; actual or contingent liabilities; and other risks and uncertainties discussed in the Company’s filings with the SEC, including the “Risk Factors” sections of the Company’s most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q. Copies of the Company’s filings with the SEC may be obtained at the “Investors & Media” section of the Company’s website at http://www.synageva.com. The Company does not undertake any obligation to update any forward-looking statements as a result of new information, future developments or otherwise, except as expressly required by applicable law or the rules and regulations of the SEC. All forward-looking statements in this Schedule 14D-9 are qualified in their entirety by this cautionary statement. The Company acknowledges that forward-looking statements made in connection with the Offer are not subject to the safe harbors created by the Private Securities Litigation Reform Act of 1995, as amended. The Company is not waiving any other defenses that may be available under applicable law.

Item 9. Exhibits.

The following Exhibits are filed with this Schedule 14D-9:

 

Exhibit
No.

  

Description

(a)(1)(A)    Prospectus/Offer to Exchange, dated May 22, 2015 (incorporated by reference to the Form S-4, filed by Alexion Pharmaceuticals, Inc. with the Securities and Exchange Commission on May 22, 2015).
(a)(1)(B)    Form of Letter of Transmittal (incorporated by reference to Exhibit 99.2 to the Form S-4 filed by Alexion Pharmaceuticals, Inc. with the Securities and Exchange Commission on May 22, 2015).
(a)(1)(C)    Form of Letter to Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees (incorporated by reference to Exhibit 99.3 to the Form S-4 filed by Alexion Pharmaceuticals, Inc. with the Securities and Exchange Commission on May 22, 2015).
(a)(1)(D)    Form of Letter to Clients for use by Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees (incorporated by reference to Exhibit 99.4 to the Form S-4 filed by Alexion Pharmaceuticals, Inc. with the Securities and Exchange Commission on May 22, 2015).
(a)(1)(E)    Form of Summary Advertisement (incorporated by reference to Exhibit (a)(5)(F) to the Schedule TO of Pulsar Merger Sub Inc., filed by Alexion Pharmaceuticals, Inc. and Pulsar Merger Sub Inc. with the Securities and Exchange Commission on May 22, 2015).
(a)(5)(A)    Joint Press release issued by Alexion Pharmaceuticals, Inc. and Synageva Biopharma Corp. dated May 6, 2015 (incorporated herein by reference to the Exhibit 99.1 to Synageva BioPharma Corp.’s Current Report on Form 8-K filed by Synageva BioPharma Corp. on May 6, 2015).
(a)(5)(B)    Opinion, May 5, 2015, of Goldman, Sachs & Co. to the Board of Directors of Synageva BioPharma Corp. (incorporated by reference to Annex A attached to this Schedule 14D-9).
(e)(1)    Agreement and Plan of Reorganization, dated May 5, 2015, among Alexion Pharmaceuticals, Inc., Pulsar Merger Sub Inc., Galaxy Merger Sub LLC and Synageva BioPharma Corp (incorporated by reference to Exhibit 2.1 to Synageva BioPharma Corp.’s Current Report on Form 8-K filed with the Securities and Exchange Commission on May 6, 2015).

 

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Exhibit
No.

  

Description

(e)(2)    Excerpts from Synageva BioPharma Corp.’s Definitive Proxy Statement on Schedule 14A related to the 2015 Annual Meeting of Stockholders as filed with the Securities and Exchange Commission on April 29, 2015. (Filed herewith)
(e)(3)    Synageva BioPharma Corp. 2005 Stock Plan, as amended (incorporated by reference to Synageva BioPharma Corp.’s Registration Statement on Form S-8 filed with the SEC on June 26, 2013).
(e)(4)    Synageva BioPharma Corp. 2005 Stock Plan-form of Option Agreement (incorporated by reference to Synageva BioPharma Corp.’s Annual Report on Form 10-K filed with the SEC on March 22, 2013).
(e)(5)    Trimeris, Inc. 2007 Stock Incentive Plan (incorporated by reference to Synageva BioPharma Corp.’s Definitive Proxy Statement on Schedule 14A filed with the SEC on March 16, 2010).
(e)(6)    Trimeris, Inc. 2007 Stock Incentive Plan—form of Option Agreement (incorporated by reference to Synageva BioPharma Corp.’s Annual Report on Form 10-K, filed with the SEC on March 17, 2008).
(e)(7)    Synageva BioPharma Corp. 2014 Equity Incentive Plan (incorporated by reference to Synageva BioPharma Corp.’s Current Report on Form 8-K filed with the SEC on June 9, 2014).
(e)(8)    Synageva BioPharma Corp. 2014 Equity Incentive Plan—form of Option Agreement, incorporated by reference to Synageva BioPharma Corp.’s Annual Report on Form 10-K (filed with the SEC on February 26, 2015).
(e)(9)    Synageva BioPharma Corp. Employee Stock Purchase Plan, as amended (incorporated by reference to Synageva BioPharma Corp.’s Registration Statement on Form S-8 filed with the SEC on December 7, 2012).
(e)(10)    Amendment No. 1 to the Synageva BioPharma Corp. Employee Stock Purchase Plan, as amended (filed herewith).
(e)(11)    Employment Agreement between Synageva BioPharma Corp. and Sanj K. Patel, effective as of November 2, 2011 (incorporated by reference to Synageva BioPharma Corp.’s Current Report on Form 8-K filed with the SEC on November 10, 2011).
(e)(12)    Employment Agreement between Synageva BioPharma Corp. and Carsten Boess, effective as of November 2, 2011 (incorporated by reference to Synageva BioPharma Corp.’s Current Report on Form 8-K filed with the SEC on November 10, 2011).
(e)(13)    Employment Agreement between Synageva BioPharma Corp. and Anthony Quinn, effective as of November 2, 2011 (incorporated by reference to Synageva BioPharma Corp.’s Current Report on Form 8-K filed with the SEC on November 10, 2011).
(e)(14)    Employment Agreement between Synageva BioPharma Corp. and Glen Williams, effective as of September 24, 2012 (incorporated by reference to Synageva BioPharma Corp.’s Annual Report on Form 10-K Filed with the SEC on March 14, 2013).
(e)(15)    Employment Agreement, effective as of September 22, 2014, between Synageva BioPharma Corp. and Robert Bazemore (incorporated by reference to Synageva BioPharma Corp.’s Current Report on Form 8-K filed with the SEC on September 22, 2014).

Annex A – Opinion, dated May 5, 2015, of Goldman, Sachs & Co. to the Company Board

Annex B – Section 262 of the Delaware General Corporation Law

 

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SIGNATURE

After due inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

Dated: May 22, 2015 SYNAGEVA BIOPHARMA CORP.
By:

/s/ Sanj K. Patel

Sanj K. Patel, President and Chief Executive Officer

 

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Annex A

200 West Street/New York, NY 10282-2198

Tel: 212-902-1000/Fax: 212-902-3000

 

LOGO

PERSONAL AND CONFIDENTIAL

May 5, 2015

Board of Directors

Synageva BioPharma Corp.

33 Hayden Avenue

Lexington, MA 02421

Gentlemen:

You have requested our opinion as to the fairness from a financial point of view to the holders of the outstanding shares of common stock, par value $0.001 per share (the “Shares”), of Synageva BioPharma Corp. (the “Company”) of the Consideration (as defined below) to be paid for each Share pursuant to the Agreement and Plan of Reorganization, dated as of May 5, 2015 (the “Agreement”), by and among Alexion Pharmaceuticals, Inc. (“Alexion”), Pulsar Merger Sub Inc. (“Purchaser”), Galaxy Merger Sub LLC and the Company. The Agreement provides for an exchange offer for all of the Shares (the “Exchange Offer”) pursuant to which Purchaser will exchange $115 in cash (the “Cash Consideration”), and 0.6581 shares of common stock, par value $0.0001 per share (“Alexion Common Stock”), of Alexion (the “Stock Consideration”; and together with the Cash Consideration, the “Consideration”) for each Share accepted. The Agreement further provides that, following completion of the Exchange Offer or if the Exchange Offer is terminated under certain circumstances specified in the Agreement, Purchaser will merge with and into the Company (the “Merger”) and each outstanding Share (other than the Shares owned by Alexion, any subsidiary of Alexion or the Company or any Dissenting Shares (as defined in the Agreement)) will be converted into the right to receive the Consideration.

Goldman, Sachs & Co. and its affiliates are engaged in advisory, underwriting and financing, principal investing, sales and trading, research, investment management and other financial and non-financial activities and services for various persons and entities. Goldman, Sachs & Co. and its affiliates and employees, and funds or other entities they manage or in which they invest or have other economic interests or with which they co-invest, may at any time purchase, sell, hold or vote long or short positions and investments in securities, derivatives, loans, commodities, currencies, credit default swaps and other financial instruments of the Company, Alexion, any of their respective affiliates and third parties, including Baker Bros. Advisors LP (“BB”), an affiliate of significant stockholders of the Company, and its affiliates and portfolio companies or any currency or commodity that may be involved in the transaction contemplated by the Agreement (the “Transaction”). We have acted as financial advisor to the Company in connection with, and have participated in certain of the negotiations leading to, the Transaction. We expect to receive fees for our services in connection with the Transaction, the principal portion of which is contingent upon consummation of the Transaction, and the Company has agreed to reimburse certain of our expenses arising, and indemnify us against certain liabilities that may arise, out of our engagement. We have provided certain financial advisory and/or underwriting services to the Company and/or its affiliates from time to time for which our Investment Banking Division has received, and may receive, compensation, including having acted as joint lead bookrunning manager with respect to the public offering of 3,450,000 Shares in January 2015 and the public offering of 2,300,000 Shares in March 2014 and as lead bookrunning manager with respect to the public offering of 3,162,500 Shares in September 2013. We also have provided certain financial advisory and/or underwriting services from time to time to companies in which funds advised by BB hold or

 

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have held equity interests for which our Investment Banking Division has received, and may receive, compensation, including having acted as joint lead bookrunning manager in connection with the public offering of 23,000,000 shares of common stock of Idera Pharmaceuticals, Inc. in February 2015, as financial advisor to InterMune Inc. in connection with its sale in September 2014, as financial advisor to ViroPharma Incorporated in connection with its sale in January 2014, and as joint bookrunning manager in connection with the private placement of 0.375% convertible senior notes due 2018 (aggregate principal amount $375,000,000) and 1.25% convertible senior notes due 2020 (aggregate principal amount $375,000,000) of Incyte Corporation in November 2013. We may also in the future provide financial advisory and/or underwriting services to the Company and Alexion and their respective affiliates and to BB and companies in which funds advised by BB hold equity interests for which our Investment Banking Division may receive compensation. Affiliates of Goldman, Sachs & Co. also may have co-invested with BB and funds advised by BB from time to time and may have invested in limited partnership units of funds advised by BB from time to time and may do so in the future. In addition, a director of The Goldman Sachs Group is a director of Alexion.

In connection with this opinion, we have reviewed, among other things, the Agreement; annual reports to stockholders and Annual Reports on Form 10-K of the Company and Alexion for the five fiscal years ended December 31, 2014; certain interim reports to stockholders and Quarterly Reports on Form 10-Q of the Company and Alexion; certain other communications from the Company and Alexion to their respective stockholders; certain publicly available research analyst reports for the Company and Alexion; and certain internal financial analyses and forecasts for the Company and certain financial analyses and forecasts for Alexion, in each case as prepared by management of the Company and approved for our use by the Company (the “Forecasts”), and certain operating synergies projected by management of the Company to result from the Transaction, as approved for our use by the Company (the “Synergies”). We have also held discussions with members of the senior managements of the Company and Alexion regarding their assessment of the strategic rationale for, and the potential benefits of, the Transaction and the past and current business operations, financial condition and future prospects of Alexion and with members of the senior management of the Company regarding their assessment of the past and current business operations, financial condition and future prospects of the Company; reviewed the reported price and trading activity for the Shares and Alexion Common Stock; compared certain financial and stock market information for the Company and Alexion with similar information for certain other companies the securities of which are publicly traded; reviewed the financial terms of certain recent business combinations in the biopharmaceutical industry; and performed such other studies and analyses, and considered such other factors, as we deemed appropriate.

For purposes of rendering this opinion, we have, with your consent, relied upon and assumed the accuracy and completeness of all of the financial, legal, regulatory, tax, accounting and other information provided to, discussed with or reviewed by, us, without assuming any responsibility for independent verification thereof. In that regard, we have assumed with your consent that the Forecasts and the Synergies have been reasonably prepared on a basis reflecting the best currently available estimates and judgments of the management of the Company. We have not made an independent evaluation or appraisal of the assets and liabilities (including any contingent, derivative or other off-balance-sheet assets and liabilities) of the Company or Alexion or any of their respective affiliates and we have not been furnished with any such evaluation or appraisal. We have assumed that all governmental, regulatory or other consents and approvals necessary for the consummation of the Transaction will be obtained without any adverse effect on the Company or Alexion or on the expected benefits of the Transaction in any way meaningful to our analysis. We have assumed that the Transaction will be consummated on the terms set forth in the Agreement, without the waiver or modification of any term or condition the effect of which would be in any way meaningful to our analysis.

Our opinion does not address the underlying business decision of the Company to engage in the Transaction, or the relative merits of the Transaction as compared to any strategic alternatives that may be available to the Company; nor does it address any legal, regulatory, tax or accounting matters. We were not requested to solicit, and did not solicit, interest from other parties with respect to an acquisition of, or other business combination with, the Company or any other alternative transaction. This opinion addresses only the fairness from a financial

 

A-2


point of view to the holders of Shares, as of the date hereof, of the Consideration to be paid to such holders pursuant to the Agreement. We do not express any view on, and our opinion does not address, any other term or aspect of the Agreement or Transaction or any term or aspect of any other agreement or instrument contemplated by the Agreement or entered into or amended in connection with the Transaction, including, the fairness of the Transaction to, or any consideration received in connection therewith by, the holders of any other class of securities, creditors, or other constituencies of the Company; nor as to the fairness of the amount or nature of any compensation to be paid or payable to any of the officers, directors or employees of the Company, or class of such persons, in connection with the Transaction, whether relative to the Consideration to be paid to the holders of Shares pursuant to the Agreement or otherwise. We are not expressing any opinion as to the prices at which Alexion Common Stock will trade at any time or as to the impact of the Transaction on the solvency or viability of the Company or Alexion or the ability of the Company or Alexion to pay their respective obligations when they come due. Our opinion is necessarily based on economic, monetary, market and other conditions as in effect on, and the information made available to us as of, the date hereof and we assume no responsibility for updating, revising or reaffirming this opinion based on circumstances, developments or events occurring after the date hereof. Our advisory services and the opinion expressed herein are provided for the information and assistance of the Board of Directors of the Company in connection with its consideration of the Transaction and such opinion does not constitute a recommendation as to whether or not any holder of Shares should tender such Shares in connection with the Exchange Offer, how any holder of Shares should vote with respect to the Merger or any other matter. This opinion has been approved by a fairness committee of Goldman, Sachs & Co.

Based upon and subject to the foregoing, it is our opinion that, as of the date hereof, the Consideration to be paid to the holders of Shares pursuant to the Agreement is fair from a financial point of view to such holders.

Very truly yours,

 

/s/ Goldman, Sachs & Co.

(GOLDMAN, SACHS & CO.)

 

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Annex B

§ 262 Appraisal rights.

(a) Any stockholder of a corporation of this State who holds shares of stock on the date of the making of a demand pursuant to subsection (d) of this section with respect to such shares, who continuously holds such shares through the effective date of the merger or consolidation, who has otherwise complied with subsection (d) of this section and who has neither voted in favor of the merger or consolidation nor consented thereto in writing pursuant to § 228 of this title shall be entitled to an appraisal by the Court of Chancery of the fair value of the stockholder’s shares of stock under the circumstances described in subsections (b) and (c) of this section. As used in this section, the word “stockholder” means a holder of record of stock in a corporation; the words “stock” and “share” mean and include what is ordinarily meant by those words; and the words “depository receipt” mean a receipt or other instrument issued by a depository representing an interest in 1 or more shares, or fractions thereof, solely of stock of a corporation, which stock is deposited with the depository.

(b) Appraisal rights shall be available for the shares of any class or series of stock of a constituent corporation in a merger or consolidation to be effected pursuant to § 251 (other than a merger effected pursuant to § 251(g) of this title and, subject to paragraph (b)(3) of this section, § 251(h) of this title), § 252, § 254, § 255, § 256, § 257, §258, § 263 or § 264 of this title:

(1) Provided, however, that, except as expressly provided in § 363(b) of this title, no appraisal rights under this section shall be available for the shares of any class or series of stock, which stock, or depository receipts in respect thereof, at the record date fixed to determine the stockholders entitled to receive notice of the meeting of stockholders to act upon the agreement of merger or consolidation, were either: (i) listed on a national securities exchange or (ii) held of record by more than 2,000 holders; and further provided that no appraisal rights shall be available for any shares of stock of the constituent corporation surviving a merger if the merger did not require for its approval the vote of the stockholders of the surviving corporation as provided in § 251(f) of this title.

(2) Notwithstanding paragraph (b)(1) of this section, appraisal rights under this section shall be available for the shares of any class or series of stock of a constituent corporation if the holders thereof are required by the terms of an agreement of merger or consolidation pursuant to §§ 251, 252, 254, 255, 256, 257, 258, 263 and 264 of this title to accept for such stock anything except:

a. Shares of stock of the corporation surviving or resulting from such merger or consolidation, or depository receipts in respect thereof;

b. Shares of stock of any other corporation, or depository receipts in respect thereof, which shares of stock (or depository receipts in respect thereof) or depository receipts at the effective date of the merger or consolidation will be either listed on a national securities exchange or held of record by more than 2,000 holders;

c. Cash in lieu of fractional shares or fractional depository receipts described in the foregoing paragraphs (b)(2)a. and b. of this section; or

d. Any combination of the shares of stock, depository receipts and cash in lieu of fractional shares or fractional depository receipts described in the foregoing paragraphs (b)(2)a., b. and c. of this section.

(3) In the event all of the stock of a subsidiary Delaware corporation party to a merger effected under § 251(h), § 253 or § 267 of this title is not owned by the parent immediately prior to the merger, appraisal rights shall be available for the shares of the subsidiary Delaware corporation.

 

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(4) In the event of an amendment to a corporation’s certificate of incorporation contemplated by § 363(a) of this title, appraisal rights shall be available as contemplated by § 363(b) of this title, and the procedures of this section, including those set forth in subsections (d) and (e) of this section, shall apply as nearly as practicable, with the word “amendment” substituted for the words “merger or consolidation,” and the word “corporation” substituted for the words “constituent corporation” and/or “surviving or resulting corporation.”

(c) Any corporation may provide in its certificate of incorporation that appraisal rights under this section shall be available for the shares of any class or series of its stock as a result of an amendment to its certificate of incorporation, any merger or consolidation in which the corporation is a constituent corporation or the sale of all or substantially all of the assets of the corporation. If the certificate of incorporation contains such a provision, the procedures of this section, including those set forth in subsections (d) and (e) of this section, shall apply as nearly as is practicable.

(d) Appraisal rights shall be perfected as follows:

(1) If a proposed merger or consolidation for which appraisal rights are provided under this section is to be submitted for approval at a meeting of stockholders, the corporation, not less than 20 days prior to the meeting, shall notify each of its stockholders who was such on the record date for notice of such meeting (or such members who received notice in accordance with §255(c) of this title) with respect to shares for which appraisal rights are available pursuant to subsection (b) or (c) of this section that appraisal rights are available for any or all of the shares of the constituent corporations, and shall include in such notice a copy of this section and, if 1 of the constituent corporations is a nonstock corporation, a copy of § 114 of this title. Each stockholder electing to demand the appraisal of such stockholder’s shares shall deliver to the corporation, before the taking of the vote on the merger or consolidation, a written demand for appraisal of such stockholder’s shares. Such demand will be sufficient if it reasonably informs the corporation of the identity of the stockholder and that the stockholder intends thereby to demand the appraisal of such stockholder’s shares. A proxy or vote against the merger or consolidation shall not constitute such a demand. A stockholder electing to take such action must do so by a separate written demand as herein provided. Within 10 days after the effective date of such merger or consolidation, the surviving or resulting corporation shall notify each stockholder of each constituent corporation who has complied with this subsection and has not voted in favor of or consented to the merger or consolidation of the date that the merger or consolidation has become effective; or

(2) If the merger or consolidation was approved pursuant to § 228, § 251(h), § 253, or § 267 of this title, then either a constituent corporation before the effective date of the merger or consolidation or the surviving or resulting corporation within 10 days thereafter shall notify each of the holders of any class or series of stock of such constituent corporation who are entitled to appraisal rights of the approval of the merger or consolidation and that appraisal rights are available for any or all shares of such class or series of stock of such constituent corporation, and shall include in such notice a copy of this section and, if 1 of the constituent corporations is a nonstock corporation, a copy of § 114 of this title. Such notice may, and, if given on or after the effective date of the merger or consolidation, shall, also notify such stockholders of the effective date of the merger or consolidation. Any stockholder entitled to appraisal rights may, within 20 days after the date of mailing of such notice or, in the case of a merger approved pursuant to § 251(h) of this title, within the later of the consummation of the tender or exchange offer contemplated by § 251(h) of this title and 20 days after the date of mailing of such notice, demand in writing from the surviving or resulting corporation the appraisal of such holder’s shares. Such demand will be sufficient if it reasonably informs the corporation of the identity of the stockholder and that the stockholder intends thereby to demand the appraisal of such holder’s shares. If such notice did not notify stockholders of the effective date of the merger or consolidation, either (i) each such constituent corporation shall send a second notice before the effective date of the merger or consolidation notifying each of the holders of any class or series of stock of such constituent corporation that are entitled to appraisal rights of the effective date of the merger or consolidation or (ii) the surviving or resulting corporation shall send such a second notice to all such holders on or within 10 days after such effective date; provided, however, that if such second notice is sent more than 20 days following the sending of the first notice or, in the case of a merger approved pursuant to §

 

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251(h) of this title, later than the later of the consummation of the tender or exchange offer contemplated by § 251(h) of this title and 20 days following the sending of the first notice, such second notice need only be sent to each stockholder who is entitled to appraisal rights and who has demanded appraisal of such holder’s shares in accordance with this subsection. An affidavit of the secretary or assistant secretary or of the transfer agent of the corporation that is required to give either notice that such notice has been given shall, in the absence of fraud, be prima facie evidence of the facts stated therein. For purposes of determining the stockholders entitled to receive either notice, each constituent corporation may fix, in advance, a record date that shall be not more than 10 days prior to the date the notice is given, provided, that if the notice is given on or after the effective date of the merger or consolidation, the record date shall be such effective date. If no record date is fixed and the notice is given prior to the effective date, the record date shall be the close of business on the day next preceding the day on which the notice is given.

(e) Within 120 days after the effective date of the merger or consolidation, the surviving or resulting corporation or any stockholder who has complied with subsections (a) and (d) of this section hereof and who is otherwise entitled to appraisal rights, may commence an appraisal proceeding by filing a petition in the Court of Chancery demanding a determination of the value of the stock of all such stockholders. Notwithstanding the foregoing, at any time within 60 days after the effective date of the merger or consolidation, any stockholder who has not commenced an appraisal proceeding or joined that proceeding as a named party shall have the right to withdraw such stockholder’s demand for appraisal and to accept the terms offered upon the merger or consolidation. Within 120 days after the effective date of the merger or consolidation, any stockholder who has complied with the requirements of subsections (a) and (d) of this section hereof, upon written request, shall be entitled to receive from the corporation surviving the merger or resulting from the consolidation a statement setting forth the aggregate number of shares not voted in favor of the merger or consolidation and with respect to which demands for appraisal have been received and the aggregate number of holders of such shares. Such written statement shall be mailed to the stockholder within 10 days after such stockholder’s written request for such a statement is received by the surviving or resulting corporation or within 10 days after expiration of the period for delivery of demands for appraisal under subsection (d) of this section hereof, whichever is later. Notwithstanding subsection (a) of this section, a person who is the beneficial owner of shares of such stock held either in a voting trust or by a nominee on behalf of such person may, in such person’s own name, file a petition or request from the corporation the statement described in this subsection.

(f) Upon the filing of any such petition by a stockholder, service of a copy thereof shall be made upon the surviving or resulting corporation, which shall within 20 days after such service file in the office of the Register in Chancery in which the petition was filed a duly verified list containing the names and addresses of all stockholders who have demanded payment for their shares and with whom agreements as to the value of their shares have not been reached by the surviving or resulting corporation. If the petition shall be filed by the surviving or resulting corporation, the petition shall be accompanied by such a duly verified list. The Register in Chancery, if so ordered by the Court, shall give notice of the time and place fixed for the hearing of such petition by registered or certified mail to the surviving or resulting corporation and to the stockholders shown on the list at the addresses therein stated. Such notice shall also be given by 1 or more publications at least 1 week before the day of the hearing, in a newspaper of general circulation published in the City of Wilmington, Delaware or such publication as the Court deems advisable. The forms of the notices by mail and by publication shall be approved by the Court, and the costs thereof shall be borne by the surviving or resulting corporation.

(g) At the hearing on such petition, the Court shall determine the stockholders who have complied with this section and who have become entitled to appraisal rights. The Court may require the stockholders who have demanded an appraisal for their shares and who hold stock represented by certificates to submit their certificates of stock to the Register in Chancery for notation thereon of the pendency of the appraisal proceedings; and if any stockholder fails to comply with such direction, the Court may dismiss the proceedings as to such stockholder.

(h) After the Court determines the stockholders entitled to an appraisal, the appraisal proceeding shall be conducted in accordance with the rules of the Court of Chancery, including any rules specifically governing

 

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appraisal proceedings. Through such proceeding the Court shall determine the fair value of the shares exclusive of any element of value arising from the accomplishment or expectation of the merger or consolidation, together with interest, if any, to be paid upon the amount determined to be the fair value. In determining such fair value, the Court shall take into account all relevant factors. Unless the Court in its discretion determines otherwise for good cause shown, interest from the effective date of the merger through the date of payment of the judgment shall be compounded quarterly and shall accrue at 5% over the Federal Reserve discount rate (including any surcharge) as established from time to time during the period between the effective date of the merger and the date of payment of the judgment. Upon application by the surviving or resulting corporation or by any stockholder entitled to participate in the appraisal proceeding, the Court may, in its discretion, proceed to trial upon the appraisal prior to the final determination of the stockholders entitled to an appraisal. Any stockholder whose name appears on the list filed by the surviving or resulting corporation pursuant to subsection (f) of this section and who has submitted such stockholder’s certificates of stock to the Register in Chancery, if such is required, may participate fully in all proceedings until it is finally determined that such stockholder is not entitled to appraisal rights under this section.

(i) The Court shall direct the payment of the fair value of the shares, together with interest, if any, by the surviving or resulting corporation to the stockholders entitled thereto. Payment shall be so made to each such stockholder, in the case of holders of uncertificated stock forthwith, and the case of holders of shares represented by certificates upon the surrender to the corporation of the certificates representing such stock. The Court’s decree may be enforced as other decrees in the Court of Chancery may be enforced, whether such surviving or resulting corporation be a corporation of this State or of any state.

(j) The costs of the proceeding may be determined by the Court and taxed upon the parties as the Court deems equitable in the circumstances. Upon application of a stockholder, the Court may order all or a portion of the expenses incurred by any stockholder in connection with the appraisal proceeding, including, without limitation, reasonable attorney’s fees and the fees and expenses of experts, to be charged pro rata against the value of all the shares entitled to an appraisal.

(k) From and after the effective date of the merger or consolidation, no stockholder who has demanded appraisal rights as provided in subsection (d) of this section shall be entitled to vote such stock for any purpose or to receive payment of dividends or other distributions on the stock (except dividends or other distributions payable to stockholders of record at a date which is prior to the effective date of the merger or consolidation); provided, however, that if no petition for an appraisal shall be filed within the time provided in subsection (e) of this section, or if such stockholder shall deliver to the surviving or resulting corporation a written withdrawal of such stockholder’s demand for an appraisal and an acceptance of the merger or consolidation, either within 60 days after the effective date of the merger or consolidation as provided in subsection (e) of this section or thereafter with the written approval of the corporation, then the right of such stockholder to an appraisal shall cease. Notwithstanding the foregoing, no appraisal proceeding in the Court of Chancery shall be dismissed as to any stockholder without the approval of the Court, and such approval may be conditioned upon such terms as the Court deems just; provided, however that this provision shall not affect the right of any stockholder who has not commenced an appraisal proceeding or joined that proceeding as a named party to withdraw such stockholder’s demand for appraisal and to accept the terms offered upon the merger or consolidation within 60 days after the effective date of the merger or consolidation, as set forth in subsection (e) of this section.

(l) The shares of the surviving or resulting corporation to which the shares of such objecting stockholders would have been converted had they assented to the merger or consolidation shall have the status of authorized and unissued shares of the surviving or resulting corporation.

 

B-4



Exhibit (e)(2)

Excerpts from Synageva BioPharma Corp.’s Definitive Proxy Statement on Schedule 14A related to the 2015 Annual Meeting of Stockholders as filed with the Securities and Exchange Commission on April 28, 2015.

BENEFICIAL OWNERSHIP OF COMMON STOCK

The following table sets forth certain information as of April 10, 2015 (except as otherwise noted) regarding the beneficial ownership (as defined by the Securities and Exchange Commission, or SEC) of our common stock of: each named executive officer listed in the Summary Compensation Table below; each director; and all directors and executive officers of Synageva as a group.

 

Named Executive Officers and Directors:

     

Felix J. Baker(8)

     11,910,144         31.97

Robert Bazemore(9)

     —           *   

Stephen R. Biggar(10)

     37,602         *   

Carsten Boess(11)

     49,824         *   

Stephen R. Davis(12)

     53,500         *   

Thomas R. Malley(13)

     91,827         *   

Sanj K. Patel(14)

     337,082         *   

Barry Quart(15)

     29,876         *   

Anthony G. Quinn(16)

     157,577         *   

Thomas J. Tisch(17)

     781,578         2.11

Glen Williams(18)

     15,051         *   

Peter Wirth(19)

     29,583         *   

All executive officers and directors as a group (12 persons)(20)

     13,428,894         35.51

 

* Less than one percent.
(1) Unless otherwise indicated, the address of all persons is 33 Hayden Avenue, Lexington, MA 02421.
(2) To our knowledge, the persons named in the table have sole voting and investment power with respect to all shares of common stock shown as beneficially owned by them, subject to community property laws where applicable and the information contained in the footnotes in this table.

 

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(8) Includes 53,250 shares of common stock, which may be acquired by Dr. Baker upon the exercise of options that are exercisable within 60 days of April 10, 2015. Dr. Baker has shared voting and investment power over the 11,648,182 shares of common stock owned by Baker Bros. Advisors LP and has shared voting and investment power over 143,462 shares of common stock owned by FBB Associates. Dr. Baker disclaims beneficial ownership of these shares except to the extent of his pecuniary interests therein.
(9) Mr. Bazemore does not have any options that may be exercised within 60 days of April 10, 2015.
(10) Includes 37,500 shares of common stock which may be acquired by Dr. Biggar upon the exercise of options that are exercisable within 60 days of April 10, 2015. Excludes shares beneficially owned by Baker Bros. Advisors LP, as to which Dr. Biggar disclaims beneficial ownership.
(11) Includes 49,824 shares of common stock which may be acquired by Mr. Boess upon the exercise of options that are exercisable within 60 days of April 10, 2015.
(12) Includes 53,500 shares of common stock which may be acquired by Mr. Davis upon the exercise of options that are exercisable within 60 days of April 10, 2015.
(13) Includes 44,926 shares of common stock which may be acquired by Mr. Malley upon the exercise of options that are exercisable within 60 days of April 10, 2015.
(14) Includes 336,051 shares of common stock which may be acquired by Mr. Patel upon the exercise of options that are exercisable within 60 days of April 10, 2015.
(15) Includes 29,876 shares of common stock which may be acquired by Dr. Quart upon the exercise of options that are exercisable within 60 days of April 10, 2015.
(16) Includes 141,940 shares of common stock which may be acquired by Dr. Quinn upon the exercise of options that are exercisable within 60 days of April 10, 2015.
(17) Includes 29,583 shares of common stock which may be acquired by Mr. Tisch upon the exercise of options that are exercisable within 60 days of April 10, 2015. Does not include shares owned by Mr. Tisch’s family members, as to which Mr. Tisch disclaims beneficial ownership.
(18) Includes 14,583 shares of common stock which may be acquired by Mr. Williams upon the exercise of options that are exercisable within 60 days of April 10, 2015.
(19) Includes 29,583 shares of common stock which may be acquired by Mr. Wirth upon the exercise of options that are exercisable within 60 days of April 10, 2015.
(20) Represents the directors and executive officers of the Company as of April 10, 2015. Includes 820,616 shares of common stock which may be acquired by all directors and executive officers upon the exercise of options that are exercisable within 60 days of April 10, 2015.

 

2


EXECUTIVE COMPENSATION

Compensation Discussion and Analysis

Introduction

This Compensation Discussion and Analysis section discusses our executive officer compensation program and the decisions made with respect to 2014 compensation for our executive officers identified in the Summary Compensation Table (our named executive officers). Our named executive officers for 2014 were:

 

Name

  

Position

Sanj K. Patel    President and Chief Executive Officer
Carsten Boess    Senior Vice President, Chief Financial Officer
Robert Bazemore(1)    Chief Operating Officer
Anthony G. Quinn    Executive Vice President, Chief Medical Officer and Head of Research and Development
Glen Williams    Senior Vice President, Global Technical Operations

 

(1) Mr. Bazemore joined the Company on September 22, 2014.

The material elements of 2014 compensation paid to our named executive officers includes:

 

   

base salaries;

 

   

annual cash incentive bonuses, which were paid in December 2014; and

 

   

long-term equity-incentive awards (LTIs), which were granted in June 2014.

Relationship Between 2014 Company Performance and Compensation Decisions

The compensation of our named executive officers for 2014 is based on the performance of the Company and our individual executives during the year. It is also consistent with our compensation objectives — to focus our executive officers on the achievement of key business objectives and to align their interests with those of our stockholders. The key corporate objectives applicable to our executive officers for 2014 and the key corporate accomplishments considered in the determination of executive compensation by the Compensation Committee for each objective were as follows:

Advancement of Synageva’s Lead Program, Kanuma™ (sebelipase alfa)

In 2014, we successfully achieved multiple important corporate and product development milestones. Success in achieving these milestones enabled us to continue to develop our lead program, Kanuma™ (sebelipase alfa), and our pipeline programs, moving the Company closer toward becoming a fully integrated, global organization focused on the development, manufacturing and commercialization of therapies for patients suffering from rare and devastating diseases.

 

   

In particular, the Company made the following progress with Kanuma:

 

   

Reported positive top-line results from the phase 3 study of Kanuma in children and adults with LAL Deficiency including meeting the primary endpoint and six secondary endpoints across multiple disease abnormalities.

 

   

Submitted a Biologic License Application (BLA) to the U.S. Food and Drug Administration (FDA) for the commercialization of Kanuma in the U.S.

 

   

Submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) for the commercialization of Kanuma in the European Union.

 

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Significantly expanded its global medical and commercial operations and capabilities to support Kanuma and eventually, the pipeline programs as they mature.

Pipeline Development

 

   

In 2014, we advanced our second program, SBC-103, an enzyme replacement therapy for mucopolysaccharidosis type IIIB (MPS IIIB), or Sanfilippo B. Specifically, we filed an Investigational New Drug application (IND) with the FDA and initiated a phase I/II clinical trial.

 

   

We also advanced our next program, SBC-105, a first-mover enzyme replacement therapy in preclinical development for rare disorders of calcification, including the first planned indication for generalized arterial calcification of infancy (GACI).

 

   

In addition, we produced enzymes targeting Hunter syndrome, Fabry disease and Pompe disease with expression levels and activity that support further preclinical development.

We also further strengthened our balance sheet through an underwritten public offering in 2014 yielding net proceeds of approximately $201 million.

2014 Compensation Highlights and Key Decisions

Our compensation philosophy is to align each executive’s compensation with our short-term and long-term performance and to provide the compensation and incentives needed to attract, motivate and retain key executives who are crucial to our long-term success. Consistent with this philosophy, a significant portion of the total compensation opportunity for each of our executives is directly related to performance factors that measure our progress against our key corporate objectives, as well as the level of achievement of individual goals developed by the Compensation Committee and approved by the Board of Directors at the beginning of the year in support of such objectives.

Base salaries should be paid in the range of the market median. In 2014, the base salaries for our named executive officers, other than Dr. Quinn, were considered to be in the range of the market median and were increased between 3% and 5% for merit in alignment with the average increase for other employees of the Company and in line with industry trends. Dr. Quinn’s salary was increased 7% to bring him closer to the market median of our peer group, which is identified and discussed below.

Annual cash incentive awards reflected 2014 Company and individual performance. We seek to tie a substantial portion of an executive’s overall compensation to our performance. In 2014, as described above, we executed on our strategic plan and produced strong results and significant value creation for our stockholders, and achieved multiple strategic, operational and product objectives. The Compensation Committee determined that cash incentive awards above the target amounts described below were warranted and consistent with our philosophy of paying cash incentive bonuses based on performance.

Long-term incentive awards, particularly stock options, are an important element of compensation and value creation. We believe that equity compensation should be targeted in the range of the 75th percentile of our market peers to retain and incentivize our executives in a very competitive industry landscape. The Compensation Committee believes that a practice of granting LTIs to Synageva executives will contribute to long-term successful Company performance. In particular, the use of stock options aligns the interests of our executives with our stockholders because our executives will only realize a return on an option if Synageva’s stock price increases. Stock options do not guarantee value to the executive. We continued our practice commenced in 2012 to grant long-term equity incentive awards at or around our annual meeting, which is typically mid-year, in order to align the timing of these grants with the equity awards made to our non-employee members of the Board of Directors, as well as allow a mid-year review of Company results prior to the issuance of these awards.

 

4


Summary of Compensation Analysis

Each year, the Compensation Committee reviews and establishes Synageva’s overall executive compensation strategy. The Compensation Committee evaluates Synageva’s existing compensation program and considers whether changes are necessary or advisable due to changed conditions, Company performance, best practices or otherwise. As part of the evaluation, the Compensation Committee considers whether new programs or strategies should be introduced.

At our 2014 annual meeting of stockholders, we held an advisory vote on executive compensation. Approximately 98% of the votes cast on the proposal were in favor of our named executive officer compensation. The Compensation Committee reviewed the final 2014 say-on-pay vote results and determined that, based on its assessment, and in consideration of many of the factors described throughout this discussion, the Compensation Committee believes that the executive compensation program substantially achieved its objectives for 2014 and is well aligned with the compensation philosophies described below. The Compensation Committee did not recommend any changes to its executive compensation program for 2014.

Key decisions regarding Synageva’s 2014 executive officer compensation were made in December 2013, June 2014 and December 2014.

 

   

In December 2013, the Compensation Committee recommended the 2014 base salaries to the Board of Directors, which were approved by the Board of Directors in December 2013.

 

   

In December 2013, the Compensation Committee recommended annual cash incentive targets and, in January 2014, corporate and individual performance goals, each of which were subsequently approved by the Board of Directors in March 2014.

 

   

In June 2014, the Compensation Committee recommended to the Board of Directors and the Board of Directors approved the granting of stock options to all named executive officers.

 

   

In September 2014, the Compensation Committee recommended to the Board of Directors and the Board of Directors approved for Mr. Bazemore in connection with his hire the following compensation terms: a base salary of $480,000; annual bonus targeted at 40% of base salary; an equity grant consisting of 30,000 restricted stock units (RSUs) and 50,000 stock options, each vesting over four years; a sign-on bonus in the amount of $100,000; and relocation assistance consisting of the cost of temporary housing for up to nine months and $100,000 relocation bonus to be paid at the time of his full relocation to Massachusetts.

 

   

In December 2014, the Compensation Committee recommended to the Board of Directors and the Board of Directors approved annual cash incentive payments for 2014 performance.

Executive Compensation Philosophy

The primary objective of our executive compensation policy is to attract, retain and motivate the key executives necessary for our short- and long-term success. We seek to tie short- and long-term cash and equity incentives to employee performance, including the achievement of measurable corporate and individual objectives, and to align executives’ incentives with stockholder value. The Compensation Committee seeks to implement its compensation programs in a way that ties a substantial portion of an executive’s overall compensation to Synageva’s performance and each element of an individual’s compensation is evaluated and determined in consideration of such person’s contribution and performance. With the exception of Mr. Patel, who is guaranteed a minimum annual cash incentive payment of 25% of his base salary, no executive is guaranteed a cash or equity incentive award and such incentives are determined at levels that the Compensation Committee believes drives performance.

 

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The Compensation Committee approves compensation programs based on certain compensation philosophies, including the following:

 

   

Pay for performance. Compensation programs should reward performance, typically demonstrated through the achievement of corporate and individual performance objectives. Company performance is a key consideration in determining employee compensation. The Compensation Committee believes that compensation for Synageva’s employees serving in the most senior management positions of the Company should be most closely linked to corporate performance and increasing stockholder value. We structure our programs to deliver greater rewards when corporate and individual performance exceeds expectations or performance objectives. If corporate or individual performance is short of expectations, or if objectives are not achieved, our compensation programs are structured so that they deliver lower compensation.

 

   

Attract, retain and motivate. Compensation programs must help Synageva attract, retain and motivate highly talented individuals with necessary skills and demonstrated abilities who will contribute to the success of Synageva by executing its short- and long-term strategic plans.

 

   

Competitive with peer group. Executive compensation should be considered in comparison with compensation paid by market peers to ensure that Synageva is competitive with other companies who compete with us for talent.

 

   

Balanced combination of compensation elements. Compensation programs should include a balance of cash and equity incentives to reward short-term and long-term performance. Each element of compensation should be used in a way that drives certain behavior, recognizing that different elements may be effectively used to drive different behavior. For example, LTIs are used to align the interests of our executive officers more closely with stockholders through equity ownership while our annual cash incentives are used to motivate individuals to achieve short-term objectives.

 

   

Fair and consistent. The overall structure of Synageva’s compensation programs should be similar across its global organization, taking into account grade-level, geographical and local considerations, and should reward employees based on responsibilities and performance.

Role of the Compensation Committee

Our executive compensation policy is set by the Compensation Committee, and the Compensation Committee is also responsible for approving the compensation of our named executive officers for recommendation to the full Board of Directors. The Compensation Committee regularly reassesses and reviews our compensation policy and programs.

Compensation determinations are not based on a rigid mathematical formula but rather multiple factors. The Compensation Committee undertakes an annual benchmarking exercise to compare each executive’s proposed compensation to that of individuals in similar positions at a peer group of companies. Generally, the Compensation Committee seeks to target base salary and target annual cash incentives for each executive in the range of the median of the peer group and LTIs in the range of the 75th percentile.

The Compensation Committee also evaluates, at the end of the year, the annual performance of Synageva and the Chief Executive Officer (CEO) by assessing the achievement of Synageva’s objectives, which are approved at the beginning of each year, and determining the level of achievement which is calculated as a percentage of the objective. The Compensation Committee reviews and approves the CEO’s evaluation of individual performance of Synageva’s other executive officers, including an assessment of achievement of individual objectives, which are also approved at the beginning of each year. Finally, the Compensation Committee takes into account each individual’s contributions in resolving unanticipated matters, general economic conditions, and any other factors the Compensation Committee deems relevant. Per its charter, the Compensation Committee may form subcommittees and delegate authority to any subcommittee or other administrator, as appropriate.

 

6


Role of Executives in 2014 Compensation Decisions

It is Synageva’s policy that no executive officer participates or makes recommendations regarding his or her own compensation.

A small number of executives generally attend Compensation Committee meetings, including the Company’s CEO and the Senior Vice President, Human Resources. Executive sessions of the Compensation Committee are conducted without any Synageva executives.

The CEO, with limited staff and management support, works with the Compensation Committee and our compensation consultant to determine compensation recommendations and achievement of individual performance goals for our executive officers other than himself. His recommendations are submitted to the Compensation Committee for review, discussion, modification and recommendation to the full Board of Directors.

The Compensation Committee is responsible for evaluating and determining CEO compensation for recommendation to the full Board of Directors and works directly with the compensation consultant, with limited support from Synageva staff and without input from the CEO.

Role of the Compensation Consultant

In 2014, after evaluating the performance of its compensation consultant, Compensia, Inc. (Compensia), the Compensation Committee again retained Compensia as an external, independent executive compensation consultant. The Compensation Committee uses the analysis prepared by the consultant as part of its periodic review of Synageva’s executive and director compensation practices. The consultant reports directly to the Compensation Committee, and the Compensation Committee has the final authority to hire and terminate the consultant. The Compensation Committee evaluates the consultant annually.

Compensia attends certain meetings of the Compensation Committee, as requested, and may communicate with the Compensation Committee chairman between meetings; however, the Compensation Committee makes all decisions regarding the compensation of our executive officers.

Compensia provided advice, information and recommendations directly to, and at the request of, the Compensation Committee, and the Compensation Committee’s decisions regarding the components and amounts of executive and director compensation were informed by the analysis and input of Compensia. The Compensation Committee assessed Compensia’s independence in 2014. The Compensation Committee determined that Compensia was independent and there were no conflicts of interest that would impact the advice to the Compensation Committee from Compensia and the representative of Compensia who advises the committee on executive compensation matters.

Components of Compensation—General

The components of our executive compensation program include the following:

 

   

base salary;

 

   

annual cash incentives;

 

   

long-term equity-based incentives;

 

   

severance benefits; and

 

   

certain other limited personal benefits.

The Compensation Committee believes that each component of compensation should be used in a manner that drives certain conduct. The Compensation Committee believes that base salary should provide a secure,

 

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fixed amount of compensation to attract and retain highly talented individuals, while the second element of cash compensation, annual cash incentives, should be used as a tool to motivate executives to achieve short-term, annual goals. Meanwhile, LTIs more closely align the interests of our executives with those of our stockholders.

When establishing annual incentive compensation opportunities, the Compensation Committee evaluates the 50th and 75th percentiles of the peer group for similar positions to understand where these opportunities fall relative to the competitive market. In making compensation determinations, the Compensation Committee considers each component of compensation in relation to the total amount of compensation paid and whether the compensation package as a whole adequately compensates each executive for Synageva’s performance during the past year and each executive’s contribution to such performance.

In consideration of Synageva’s 2013 performance, the Compensation Committee sought to achieve 2014 total compensation between the 50th and 75th percentiles of the market peers, even if certain components were below or above such level. Generally, 2014 base salary and target annual cash incentives for each named executive were in the range of the median for our peer group at the time such compensation was determined, while LTIs were above the market median and in the range of the 75th percentile.

We discuss each component of our compensation program in more detail below, including the rationale for 2014 compensation decisions.

Peer Group Analysis

The Compensation Committee believes that executive compensation should be considered in comparison with compensation paid by market peers to ensure that Synageva is competitive with other companies who compete with us for talent. The Compensation Committee, together with its compensation consultant, reviews the peer group on a regular basis and approves the peer group annually. The Compensation Committee believes that the factors listed below are the most important to consider for its determination of the Synageva peer group:

 

   

Industry. A peer company should operate in the same industry.

 

   

Recruiting. A peer company should compete with Synageva for talent.

 

   

Commercial Capabilities. A peer company’s commercial capabilities should reflect the capabilities Synageva has established and is developing. The successful development and commercialization of drugs for orphan diseases require substantial investments in medical education to support clinical development. For this reason, the development of orphan drugs typically require the establishment of medical affairs and commercial capabilities earlier than that required for the development of drugs for more traditional markets. The Compensation Committee considers the commercial capabilities that peer companies have established or are developing.

 

   

Market Capitalization. A peer company’s market capitalization should be similar, but not necessarily identical, to Synageva’s market capitalization as an indicator of financial performance, investment and size.

 

   

Employees. A peer company’s size should be similar to Synageva’s. The Compensation Committee measures size by comparing the number of employees which the Compensation Committee believes is the appropriate metric and is the metric used by many companies and proxy advisory firms.

 

   

Stage of Development. A peer company should be at a similar stage of development.

 

   

Orphan Disease Focus. A peer company should be focused on the development and commercialization of therapeutic products for rare diseases.

 

   

Location. A peer company should be in a geographic location that has similar executive compensation levels as Synageva.

 

8


The Compensation Committee endeavors to select peer companies that exhibit all of the factors set forth above but recognizes that it cannot develop a peer group in which all companies exhibit all factors. All of Synageva’s peer companies are in the same industry and have the same or similar Standard Industrial Classification (SIC) Code. However, the similarities between Synageva and a particular peer company with respect to any of the other factors listed above, such as commercial capabilities, will vary. Further, with respect to a particular factor, such as orphan disease focus, there may be no similarity. The Compensation Committee believes that in some cases the peer group should be designed to purposefully include companies that are not identical to Synageva. For example, the Compensation Committee believes that the peer group should include companies with both higher as well as lower market capitalization than Synageva to fairly represent the median compensation paid to executives at such companies as a group. However, in some cases, the lack of similarity is not by design of the peer group, but rather because there are not a sufficient number of companies that are similar to Synageva with respect to such factor. For example, not all companies in Synageva’s peer group are in the same stage of clinical development. The Compensation Committee believes that it is not possible to eliminate such differences entirely and recognizes the possibility that shifts in its peer group selection could influence executive compensation decisions. The Compensation Committee seeks to mitigate such risk by not relying entirely on any one or two factors, but to include companies that represent as many of the factors listed above as possible. The Compensation Committee also seeks to avoid reliance on one or two factors alone, such as commercial capabilities and market capitalization, because doing so would likely alter, possibly significantly, the results of the benchmarking exercise and the Compensation Committee’s determinations. The Compensation Committee believes that the mix of factors listed above results in a balanced and representative peer group, taking into consideration Synageva’s operations and needs, and the Compensation Committee expects that use of such peer group will result in compensation decisions that support the Company’s compensation philosophy and objectives.

The Compensation Committee generally compares the compensation of each named executive officer in relation to both the median and the 75th percentile of the peer group for similar positions at the peer group. The Compensation Committee also takes into account various factors such as the unique characteristics of the individual’s position, and any succession and retention considerations.

Over the course of 2014, the Compensation Committee, together with Compensia, reviewed a peer group that had been selected in 2013 based on its evaluation of several factors, including the factors described above under Peer Group Analysis. Due to the changes to the independent status of Idenix Pharmaceuticals, Inc. and ViroPharma Incorporated and to better align our peer group with Synageva’s size and market capitalization, the peer group was updated in May of 2014 to assist the Compensation Committee in determining the appropriate long-term incentive compensation prior to the equity grants in June of 2014.

The 2013 peer group used by the Compensation Committee to assist in the determination of 2014 base salary compensation and 2014 annual cash incentive bonus targets was comprised of the following companies:

 

Achillion Pharmaceuticals, Inc.

   ImmunoGen, Inc.

Aegerion Therapeutics, Inc.

   Infinity Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc.

   InterMune, Inc.

ARIAD Pharmaceuticals, Inc.

   Lexicon Pharmaceuticals, Inc.

AVEO Pharmaceuticals, Inc.

   Momenta Pharmaceuticals, Inc.

BioMarin Pharmaceuticals Inc.

   Nektar Therapeutics

Clovis Oncology, Inc.

   Pharmacyclics, Inc.

Dynavax Technologies Corporation

   ViroPharma Incorporated

Idenix Pharmaceuticals, Inc.

  

Compensia collected its data from peer group proxy statements and from the 2013 Radford Global Life Sciences Survey.

 

9


The updated peer group used by the Compensation Committee to assist in the determination of 2014 long-term incentive compensation was comprised of the following companies:

 

Acadia Pharmaceuticals, Inc.

   Intercept Pharmaceuticals, Inc.

Aegerion Therapeutics, Inc.

   InterMune, Inc.

Agios Pharmaceuticals, Inc.

   Nektar Therapeutics

Alnylam Pharmaceuticals, Inc.

   Opko Health, Inc.

ARIAD Pharmaceuticals, Inc.

   Pharmacyclics, Inc.

BioMarin Pharmaceuticals Inc.

   Portola Pharmaceuticals, Inc.

Clovis Oncology, Inc.

   Seattle Genetics, Inc.

ImmunoGen, Inc.

  

Compensia collected its data from peer group proxy statements and from the 2014 Radford Global Life Sciences Survey.

The Compensation Committee places significant emphasis on the use of comparative market data. The Compensation Committee uses the market information to ensure that compensation for executives is at least competitive with the peer group. The information also provides a framework for the Compensation Committee in evaluating and awarding compensation in circumstances of superior performance. Compensia provides peer group data for each Synageva executive by matching the Synageva executive with executives in the peer group with similar titles and similar job responsibilities. The Compensation Committee also recognizes that differences exist between the duties of Synageva’s executives and those matched at the peer group of companies. The Compensation Committee considers such differences when evaluating compensation and performance.

2014 Compensation Components

As a baseline for awarding compensation and prior to making annual executive compensation decisions, the Compensation Committee evaluates Synageva’s performance for the prior year by assessing if, and the extent to which, Synageva achieved or failed to achieve the corporate goals approved by the Compensation Committee and the Board of Directors. To assist in the determination of 2015 base salaries and achievement of targets for annual cash incentive awards, the Compensation Committee evaluated Synageva’s performance in December 2014 and determined that Synageva achieved 105% of its approved corporate goals for 2014. Specifically, Synageva made the following progress:

 

   

Reported positive top-line results from the phase 3 study of Kanuma in children and adults with LAL Deficiency including meeting the primary end-point and six secondary endpoints across multiple disease abnormalities;

 

   

Submitted a BLA to the FDA for the commercialization of Kanuma in the U.S.;

 

   

Submitted a MAA to the EMA for the commercialization of Kanuma in the European Union;

 

   

Significantly expanded our global medical and commercial operations and capabilities to support Kanuma;

 

   

Filed an IND with the FDA and initiated a phase I/II clinical trial in our second program, SBC-103, an enzyme replacement therapy for mucopolysaccharidosis type IIIB (MPS IIIB), or Sanfilippo B;

 

   

Advanced our next program, SBC-105, a first-mover enzyme replacement therapy in preclinical development for rare disorders of calcification, including the first planned indication for generalized arterial calcification of infancy (GACI);

 

   

Produced enzymes targeting Hunter Syndrome, Fabry Disease and Pompe Disease with expression levels and activity that support further preclinical development; and

 

10


   

Strengthened our balance sheet through an underwritten public offering in 2014 yielding net proceeds of approximately $201 million.

In June 2014, the Compensation Committee recommended for the approval by the Board of Directors the granting of stock options for all then serving executive officers. In December 2014, the Compensation Committee reviewed the 2014 corporate goals and the goals of the individual then-serving named executive officers, other than Mr. Patel, in order to determine the payment of 2014 annual cash incentive awards and also approved 2015 base salaries and 2015 annual cash incentive targets, subject to the approval of the Board of Directors. In approving and awarding these components of compensation, the Compensation Committee determined that Synageva exceeded its 2014 corporate goals, had a strong performance in 2014, and that the Compensation Committee should seek to achieve total compensation for each executive commensurate with those accomplishments.

Base Salary

Base salary represents a secure, fixed component of an executive’s compensation. Determinations of base salary levels for our executives are established based on the position, the scope of responsibilities, and the prior relevant background, training and experience of each individual. Base salaries take into account an annual review of marketplace competitiveness with the peer group. We believe that base salaries for our executives are competitive in the industry and that Synageva’s base salary levels have contributed to our ability to successfully attract and retain highly talented executives.

In determining 2014 and 2015 base salaries, the Compensation Committee relied on the market comparisons provided by its compensation consultant. As with each other component of compensation, an executive’s base salary is evaluated together with other components of the executive’s compensation in the aggregate to ensure that the executive’s total compensation is in line with our overall compensation philosophy.

On an individual basis, 2014 and 2015 annual increases in base salary reflect marketplace competitiveness levels, the industry’s annual competitive pay practices, an individual’s contributions to Synageva’s overall performance, and length of service. Utilizing the peer group data, 2014 and 2015 base salaries of all positions for which there was available and adequate data was evaluated and compared to Synageva’s base salaries during 2013 and 2014.

In 2014, the base salaries for our named executive officers, other than Dr. Quinn, were considered to be in the range of the market median and were increased between 3% and 5% for merit in alignment with the average increase for other employees of the Company and in line with industry trends. Dr. Quinn’s salary was increased 7% to bring him closer to the market median of our peer group. Mr. Bazemore’s 2014 salary was negotiated at the time of his hiring in September 2014. In setting base salaries for 2015 and consistent with previous annual base salary evaluations, the Compensation Committee determined that base salaries for the named executive officers should be within the range of the market median. In December 2014, the Compensation Committee and the Board of Directors approved increases of 5% for Mr. Patel, and 4% each for Messrs. Boess, Bazemore and Williams. Dr. Quinn received an increase of 14% to bring him closer to the market median of our peer group.

Annual Incentive Bonuses

Synageva seeks to deliver target annual cash incentives in the range of the 50th percentile of our peer group. In 2014, and in consideration of Synageva’s strong performance, the amount of annual incentives actually paid to our named executive officers was at or above the market median of the peer companies.

Annual cash incentive bonuses are designed to reward annual achievements and to be commensurate with each executive officer’s scope of responsibilities, demonstrated leadership, management abilities and effectiveness in his role. Annual cash incentive bonuses are also intended to retain executives, to motivate executives to achieve short-term (annual) success, and to reward, in the short-term, significant contributions to

 

11


the success of Synageva. While Synageva’s policy is to pay a significant portion of its senior executives’ cash compensation in the form of annual incentive bonuses, no senior executive of Synageva, with the exception of Mr. Patel who is guaranteed a minimum bonus payout of 25% of his salary, is guaranteed an annual incentive bonus.

As noted above, the Compensation Committee first approves each executive’s target (a percentage of base salary) at the beginning of each calendar year and establishes annual corporate performance goals as well as individual goals for the executive officers, other than Mr. Patel. Corporate and individual goals are proposed by management, reviewed and approved by the Compensation Committee and also approved by the Board of Directors. The Compensation Committee considers and assigns a relative weight to each corporate goal to appropriately focus efforts on corporate goals that are intended to enhance stockholder value and an overall weight of 10% for individual goals, except for Mr. Patel who is only evaluated on achievement of the corporate goals. In December 2014, prior to approving 2014 annual incentive bonuses, the Compensation Committee evaluated Synageva’s 2014 performance by assessing if, and the extent to which, Synageva achieved or failed to achieve the corporate goals approved by the Compensation Committee and the Board of Directors for 2014. In assessing the performance of management against pre-determined goals, the Compensation Committee and the Board of Directors may consider circumstances such as the over-achievement of goals and management’s ability to capitalize on newly identified opportunities or manage through obstacles not foreseen at the time the goals were established. The Compensation Committee determined that Synageva’s 2014 performance, in total, exceeded the approved corporate goals.

In December 2013, the Compensation Committee and the Board of Directors approved the following annual cash incentive bonus targets as a percentage of base salary for 2014: 60% for Mr. Patel, 40% for Dr. Quinn, and 35% for Messrs. Boess and Williams. Mr. Bazemore’s bonus target was negotiated at the time of hire and was set at 40% under his employment agreement. The Compensation Committee believed that targets should be set in a manner consistent with Synageva’s compensation philosophy of paying for performance, and maintaining competitive compensation arrangements in order to retain and motivate our executives. The Compensation Committee set targets in the range of the median of the peer group. Actual annual cash incentive bonuses for 2014 were approved and paid in December 2014 based on the achievement of the corporate and individual goals.

Set forth below are the 2014 corporate goals, the weight assigned and Synageva’s achievement:

 

Corporate Goal

   Assigned Weight      2014
Achievement
 

(1)    Kanuma

     55         55   

•      Report top-line results from the phase 3 study of Kanuma in children and adults with LAL Deficiency

•      Submit a BLA to the FDA for the commercialization of Kanuma in the U.S.

•      Submit a MAA to the EMA for the commercialization of Kanuma in the European Union

•      Ensure adequate supply of Kanuma

•      Prepare for the future launch of Kanuma including continuing to increase awareness and knowledge of LAL Deficiency in the medical community

     

(2)    Pipeline development and research

     40         45   

•      Submission of an IND for SBC-103

•      Advance an additional pipeline candidate through proof of concept

•      Identify and advance new research targets

     

(3)    Corporate and general and administrative activities

     5         5   

•      Strengthen the balance sheet

•      Manage Company resources within budget/forecast targets

     
  

 

 

    

 

 

 

Totals:

     100         105   

 

12


To optimize achievement of corporate goals, individual goals are set in support of annual corporate goals for all executives other than Mr. Patel, and represent 10% of each named executive officer’s annual incentive bonus payment. The annual corporate goals represent the other 90% of each named executive officer’s goals. Individual goals for 2014 overlapped with our corporate goals for 2014 and consisted of sub-goals designed to achieve our corporate goals.

 

   

Mr. Boess’ individual goals were: strengthen the balance sheet; manage Company resources within budget/forecast targets; implement long-range financial planning; optimize global financial and operations management; and evaluate and execute on business development opportunities.

 

   

Dr. Quinn’s individual goals were: submit the BLA and MAA for Kanuma; submit the IND for SBC-103; progress activities to broaden application of protein manufacturing; and identify and advance new research targets.

 

   

Mr. Bazemore’s individual goals were: build global commercial infrastructure in anticipation of future commercial launch; develop and execute on initiatives to increase patient identification; and develop and optimize global medical affairs team.

 

   

Mr. Williams’ individual goals were: complete the commercial manufacturing process for Kanuma and support filing of BLA and MAA; continue to develop and optimize the technical operations team; continue to expand our product supply capabilities, enhance manufacturing for SBC-103; expand inventory for both Kanuma and SBC-103; and continue to expand our supply chain.

Prior to the December 2014 Compensation Committee meeting, Mr. Patel reviewed in detail the performance of each named executive officer, excluding himself, and considered such individual’s contributions to Synageva’s success in 2014 and recommended the annual cash incentive bonus to be paid to each individual based on the achievement of the individual goals set forth above. In making his recommendations, Mr. Patel worked closely with the Compensation Committee, relied on data provided by Compensia, and received limited support from staff and other members of management.

The Compensation Committee considered 2014 to be a strong year for Synageva. In 2014, the Company attained key strategic milestones that the Compensation Committee expects to provide long-term value to Synageva’s business, to patients and to stockholders. In particular, Synageva:

 

   

Made significant progress in the development of Kanuma. Synageva reported positive top-line results from the phase 3 study of Kanuma in children and adults with LAL Deficiency and submitted a BLA in the U.S. and MAA in Europe.

 

   

Achieved milestones for SBC-103 and the pipeline. Submitted an IND to the FDA for SBC-103 and progressed both SBC-105 and potentially bio-superior treatments for patient populations where there is still unmet medical need.

 

   

Strengthened the balance sheet. Synageva completed a follow-on offering of its common stock generating approximately $201 million of net proceeds.

Mr. Patel recommended annual cash incentives based on strong individual and corporate performance in 2014. Synageva exceeded 2014 objectives and each executive made important contributions to Synageva’s 2014 achievements. The Compensation Committee discussed Mr. Patel’s recommendations for the named executive officers and determined that annual cash incentive decisions for the named executive officers, including Mr. Patel, should reflect Synageva’s strong performance in 2014 and recognition of significant achievements.

In December 2014, Mr. Patel, Dr. Quinn, Mr. Boess and Mr. Williams received annual incentive bonuses with respect to 2014 performance of $397,641, $168,361, $136,471, and $121,139, respectively, representing 105%, 104%, 104%, and 104% of the target annual incentive bonus amounts, respectively. Mr. Bazemore

 

13


received an annual incentive bonus of $54,707 representing 104% of the target annual incentive bonus amount, prorated based on his start date of September 22, 2014.

2014 Long-Term Incentive Awards

Synageva primarily uses stock options as its LTIs, although in 2014, due to the competitive nature of the recruiting process, the Compensation Committee recommended and the Board of Directors approved a grant of RSUs for the first time as part of the new hire package for Mr. Bazemore. The Compensation Committee reviews and approves LTI grant guidelines for all positions and levels throughout the global organization other than executives (senior vice presidents and above). The LTI grant guidelines are established to ensure that Synageva’s grant practices are competitive in each jurisdiction where our employees are located. We review market data by position, level and geographical region and establish guidelines and award values that we believe enable us to attract, retain and motivate a talented, values driven workforce.

An eligible employee will receive an annual award after the employee’s performance is evaluated and the actual LTI value delivered for each individual recipient is based on the LTI guidelines and an assessment of an individual’s performance.

The Compensation Committee has not established LTI grant guidelines for its executives, including the named executive officers. Together with the compensation consultant, the Compensation Committee conducts a detailed benchmarking exercise to evaluate each executive’s award levels compared to market peers. In determining LTI awards for executives, the Compensation Committee considers:

 

   

the peer group market data;

 

   

the individual’s contribution during the prior year and year-to-date, as well as the individual’s potential contribution to Synageva’s growth and financial results;

 

   

the value of proposed awards;

 

   

corporate performance; and

 

   

the individual’s level of responsibility within Synageva.

As is the case when the amount of base salary and annual cash incentive opportunity is determined, when determining LTI values, a review of all of the executive’s compensation is conducted to ensure that an executive’s total compensation conforms to our overall philosophy and objectives.

Options are granted with an exercise price equal to the fair market value of Synageva’s common stock on the date of grant and, accordingly, will only have value if Synageva’s stock price increases. In 2014, in response to the competitive nature of his recruitment, we also granted RSUs for the first time to Mr. Bazemore as part of his new hire package. Generally, LTI awards vest over four years and the individual must be employed by Synageva as an employee, director or consultant for such awards to vest. The Compensation Committee believes that conditioning these awards on employment also serves as a valuable retention tool.

The Compensation Committee believes that long-term equity-based incentive awards are a critical element of compensation. However, like a short-term cash incentive award (or cash bonus), a long-term equity incentive award is a variable component of each employee’s compensation and no individual, including any executive, is guaranteed to receive an award or a certain value. In determining 2014 grant levels, which were evaluated in May 2014, the Compensation Committee recognized the importance of maintaining this alignment and considered Synageva’s strong 2013 and to date 2014 performance. The Compensation Committee believed that it was appropriate to set 2014 grant levels in the range of the 75th percentile of the peer group.

The Compensation Committee believes that its practice of awarding LTIs to Synageva executives has contributed to long-term successful performance, which has been demonstrated through substantial value

 

14


creation for Synageva’s stockholders. Starting in 2012, LTI awards are granted at or around our annual meeting which is typically mid-year. The timing of these awards align the timing of management and board LTI awards as well as allow a mid-year review of Company results prior to the awards.

LTIs were granted to executives (and other employees and the board of directors) in June 2014. The Compensation Committee approved LTIs to Mr. Patel, Mr. Boess, Dr. Quinn, and Mr. Williams in the amounts set forth in the table under the heading “Grants of Plan-Based Awards.” Mr. Bazemore received a new hire equity grant award that was negotiated at the time of his hire which included both stock options and RSUs in the amounts set forth in the table under the heading “Grants of Plan-Based Awards”.

Termination Based Compensation

We provide severance payments and other benefits to our executives under written employment agreements if they are terminated without cause or in certain other instances, including in connection with a change of control. We believe that executives, particularly a company’s most senior executives, often face challenges securing new employment following termination and that non-financial severance terms identify important continuing obligations of both Synageva and our executive officers, such as protection against competition and solicitation. In addition, severance provisions related to a change of control also assist in retaining high quality executives and keeping them focused on their responsibilities during any period in which a change of control may be contemplated or pending, and in providing the executives a sense of security and trust that they will be treated fairly during such transactions. For details on the severance payments our executives are entitled to, please refer to the section entitled “Potential Payments Upon Termination or Change of Control” in this proxy statement.

Personal Benefits

We generally do not provide, and executives are not entitled to, perquisites such as permanent lodging, cars or defraying the cost of personal entertainment or family travel. Mr. Bazemore received certain benefits in connection with his relocation to Lexington, MA upon his hire in 2014. The amounts paid to Mr. Bazemore in 2014 for such benefits are reflected in the Summary Compensation Table. Mr. Bazemore also received a new hire sign-on bonus of $100,000, which was negotiated at the time of his hiring in September of 2014.

Assessment of Risk

The Compensation Committee monitors the risks associated with our executive compensation programs and individual compensation decisions. The Compensation Committee has concluded that risks associated with our compensation policies and practices are within our ability to effectively monitor and manage and that the risks are not reasonably likely to have a material adverse effect on Synageva.

Other Compensation Matters

The Compensation Committee regularly reviews, assesses and discusses Synageva’s compensation programs to determine whether its practices and policies achieve Synageva’s compensation objectives and are consistent with the Company’s compensation philosophies. The Compensation Committee believes that compensation programs should be adjusted and should evolve over time due to many considerations and factors, including Synageva’s performance, Synageva’s growth, stockholder sentiment and feedback, compensation and corporate governance best practices, risk mitigation strategies, and regulatory developments. The Compensation Committee believes that Synageva’s current compensation practices have contributed to Synageva’s strong short- and long-term performance, including Synageva’s exceptional performance in 2014, and have facilitated significant stockholder value creation.

 

15


SUMMARY COMPENSATION TABLE

The following table shows the compensation paid to the Company’s Principal Executive Officer, Principal Financial Officer and its three highest compensated executive officers other than the Principal Executive Officer and Principal Financial Officer for services rendered in 2014, 2013 and 2012, as applicable.

 

Name and Principal Position

  Year     Salary
($)
    Bonus
($)
    Stock
Awards

($)(1)
    Option
Awards
($)(1)
    Non-Equity
Incentive Plan
Compensation
($)(2)
    All
Other
Compensation
($)(3)
    Total
($)
 

Sanj K. Patel

    2014        631,176        —          —          6,028,800        397,641        11,950        7,069,567   

President and Chief

Executive Officer

    2013        601,120        —          —          2,796,800        468,874        11,330        3,878,124   
    2012        578,000        —          —          2,856,400        364,140        11,200        3,809,740   

Carsten Boess

    2014        374,920        —          —          2,009,600        136,471        11,384        2,532,375   

Senior Vice President,

Chief Financial Officer

    2013        360,500        —          —          983,250        159,611        10,075        1,513,436   
    2012        350,000        —          —          868,500        124,950        10,000        1,353,450   

Robert Bazemore(4)

    2014        110,770        100,000        1,893,300        1,796,500        54,707        16,852        3,958,570   

Chief Operating Officer

    2013        —          —          —          —          —          —          —     
    2012        —          —          —          —          —          —          —     

Anthony G. Quinn

    2014        406,668        —          —          2,260,800        168,361        12,069        2,847,898   

Executive Vice President,

Chief Medical Officer and

Head of Research and Development

   

 

2013

2012

  

  

   

 

380,064

365,446

  

  

   

 

—  

—  

  

  

   

 

—  

—  

  

  

   

 

983,250

868,500

  

  

   

 

193,073

152,026

  

  

   

 

10,123

10,000

  

  

   

 

1,566,510

1,395,972

  

  

Glen Williams(5)

    2014        332,800        —          —          2,260,800        121,139        13,127        2,727,866   

Senior Vice President,

Global Technical Operations

   

 

2013

2012

  

  

   

 

320,000

75,833

  

 

   

 

—  

—  

  

  

   

 

—  

—  

  

  

   

 

874,000

1,095,600

  

 

   

 

141,120

27,365

  

 

   

 

10,190

70,000

  

 

   

 

1,345,310

1,268,798

  

  

 

(1) This column represents the grant date fair value of equity awards calculated in accordance with FASB ASC Topic 718. See Note 6 to our audited consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2014 for details as to the assumptions used to determine the fair value of the awards.
(2) Represents the annual cash incentive bonus earned by the named executive officer for services performed in 2014, 2013 and 2012.
(3) Other income for Mr. Patel includes $300 in 2014 and $1,200 for 2013 and 2012 for healthcare reimbursement benefits. All other amounts, other than amounts paid to Mr. Bazemore and Mr. Williams, as described in footnotes 4 and 5, respectively, consist of company-matching 401(k) contributions and taxable group term life insurance benefits.
(4) Mr. Bazemore’s employment commenced on September 22, 2014. The following amounts are set forth in the All Other Compensation column: We paid Mr. Bazemore a new hire sign-on bonus of $100,000 and $13,559 in connection with his relocation to Lexington, MA upon his hire in 2014. All other amounts consist of Company-matching 401(k) contributions and taxable group term life insurance benefits.
(5) Mr. Williams’ employment commenced on September 24, 2012. We paid Mr. Williams $70,000 in connection with his relocation to Lexington, MA upon his hire in 2012 and such amount is set forth in the All Other Compensation column.

 

16


Chief Executive Officer’s Employment Agreement

Following the Merger, the Board of Directors approved the terms of a new employment agreement with Sanj K. Patel, the Company’s President and Chief Executive Officer, effective as of November 2, 2011 (the “Patel Agreement”).

Under the terms of the Patel Agreement, Mr. Patel is entitled to a base salary, which was set at $631,176 per year for 2014, an annual cash bonus with a target level of 60%, and a minimum payout level of 25%, of his annual base salary. Synageva may also grant Mr. Patel equity awards each year. The performance targets related to Mr. Patel’s annual cash bonus and the terms and conditions of his equity awards are to be determined by the Compensation Committee and approved by the Board, and the actual amount of Mr. Patel’s annual cash bonus shall be determined in good faith by the Compensation Committee based on actual corporate and individual performance. Under the Patel Agreement, if Synageva terminates Mr. Patel’s employment without cause (as defined below) or Mr. Patel terminates his employment for good reason (as defined below), Mr. Patel will be entitled to the following severance:

 

   

a lump sum equal to 18 months of his base salary plus 1.5x his target annual cash bonus;

 

   

a pro-rata share of his target annual cash bonus for the year in which the termination occurs;

 

   

a one-time bonus of $25,000; and

 

   

acceleration of the vesting of all unvested equity awards held by Mr. Patel by 18 months.

If Synageva terminates Mr. Patel’s employment without cause or he resigns for good reason during the 12 months following a change of control, as defined in the agreement, Mr. Patel will be entitled to the following severance:

 

   

a lump sum equal to 24 months of his base salary plus 2x his target annual cash bonus;

 

   

a pro-rata share of his target annual cash bonus for the year in which the termination occurs;

 

   

a one-time bonus of $25,000; and

 

   

acceleration of the vesting of all unvested equity awards held by Mr. Patel by 18 months, and full vesting of all awards that were assumed or substituted in the change of control.

Under the Patel Agreement, “cause” means: (i) gross negligence or willful misconduct in performance of the executive’s duties to the Company, where such gross negligence or willful misconduct has resulted in material damage to the Company or any of its affiliates or successors; (ii) commission of any act of fraud, embezzlement or professional dishonesty with respect to the Company or any of its affiliates; (iii) commission of a felony or crime involving moral turpitude; (iv) material breach of any provision of this Agreement or any other written agreement between the executive and the Company; or (v) failure to comply with lawful directives of the Board of Directors, which has caused damage to the Company or any of its affiliates or successors.

Mr. Patel would be entitled to terminate his employment for “good reason” under the Patel Agreement if any of the following events occur without Mr. Patel’s written consent: (i) the assignment to Mr. Patel of duties materially inconsistent with his title, position, status, reporting relationships, authority, duties or responsibilities; (ii) any action by the Company which results in a diminution in Mr. Patel’s title, position, status, reporting relationships, authority, duties or responsibilities, other than insubstantial or inadvertent actions not taken in bad faith which are remedied by the Company promptly after receipt of notice thereof given by Mr. Patel; (iii) a requirement that Mr. Patel relocate his primary reporting location to a location more than 50 miles from the location of the Company’s offices in Lexington, Massachusetts; (iv) any failure by the Company to comply with certain provisions of the Patel Agreement, other than insubstantial or inadvertent failures not in bad faith which are remedied by the Company promptly after receipt of notice thereof given by Mr. Patel; (v) a material diminution in the budget over which Mr. Patel has responsibility; or (vi) a breach by the Company of any written agreement between the Company and Mr. Patel.

 

17


Executive Employment Agreements with Carsten Boess, Robert Bazemore, Anthony G. Quinn and Glen Williams

Mr. Boess and Dr. Quinn entered into employment agreements following the Merger, effective November 2, 2011. Mr. Williams entered into an employment agreement effective upon his hire on September 24, 2012. Mr. Bazemore entered into an employment agreement effective upon his hire on September 22, 2014. Collectively, we refer to these agreements at the “Executive Employment Agreements.”

Pursuant to the Executive Employment Agreements, the Company will pay Mr. Bazemore, Mr. Boess, Dr. Quinn and Mr. Williams’s annual base salaries in amounts determined by the Compensation Committee, and each executive shall be eligible to receive an annual cash bonus of up to 40%, 35%, 40% and 35% of their annual base salaries, respectively. If Synageva terminates the employment of Mr. Bazemore, Mr. Boess, Dr. Quinn or Mr. Williams without cause, as defined below, Synageva will accelerate the vesting of all of the executive’s unvested equity awards by 12 months and the executive will receive (i) cash severance payable in a lump sum equal to 9 months of his base salary for Messrs. Boess and Williams or 12 months of his base salary for Dr. Quinn and Mr. Bazemore; and (ii) a pro-rata share of his target annual cash bonus for the year in which the termination occurs. If Synageva terminates the executive without cause during the 12 months following a change of control, as defined in the agreement, the executive will receive (i) cash severance payable in a lump sum equal to 12 months of his base salary; (ii) a lump sum payment equal to the target annual cash bonus for the year in which the termination occurs; (iii) a one-time bonus of $16,500; and (iv) acceleration of all unvested equity then held by the executive by 12 months and full vesting of all awards that were assumed or substituted in the change of control.

Under the Executive Employment Agreements, “cause” means: (i) gross negligence or willful misconduct in performance of the executive’s duties to the Company, where such gross negligence or willful misconduct has resulted in material damage to the Company or any of its affiliates or successors; (ii) commission of any act of fraud, embezzlement or professional dishonesty with respect to the Company or any of its affiliates; (iii) commission of a felony or crime involving moral turpitude; (iv) material breach of any provision of the Executive Employment Agreement or any other written agreement between the executive and the Company; or (v) failure to comply with lawful directives of the CEO, which has caused damage to the Company or any of its affiliates or successors.

In connection with his appointment, Mr. Bazemore received a one-time sign-on bonus of $100,000. He also received and will continue to receive payments for the cost of temporary housing for up to nine months from his commencement of employment, and a one-time payment of $100,000 as a relocation assistance bonus at the time he relocates.

Annual Cash Bonus Plan

The Company has established an Annual Cash Bonus Plan that is administered by the Compensation Committee. Executive officers and other employees of the Company and its affiliates are eligible to participate. The Compensation Committee selects who may receive bonus awards, the criteria used to determine whether the recipient is entitled to the award, the amount payable, the relative performance period to which the award relates and other terms and conditions as the Compensation Committee deems appropriate with respect to the award.

 

18


2014 GRANTS OF PLAN-BASED AWARDS

The following table sets forth information regarding awards made to our named executive officers during the year ended December 31, 2014:

 

Name

  Type of
Award(1)
          Grant Date     Minimum
Payouts

Under
Non-Equity
Incentive
Plan

($)
    Estimated
Future Payouts
Under
Non-Equity
Incentive Plan
Awards Target
(2)($)
    All Other
Stock
Awards:
Number of
Shares of
Stock or
Units

(#)
    Option
Awards:
Numbers of
Securities
Underlying
Options

(#)
    Exercise
Price of
Option
Awards(3)
($/Sh)
    Grant Date
Fair Value
of Stock
and Option
Awards(4)
($)(#)
 

Sanj K. Patel

    SO        (5     6/4/2014        —          —          —          120,000        80.35        6,028,800   
    CBP         N/A        157,794        378,706        —          —          —          —     

Carsten Boess

    SO        (5     6/4/2014        —          —          —          40,000        80.35        2,009,600   
    CBP         N/A        —          131,222        —          —          —          —     

Robert Bazemore

    SO        (6     9/23/2014        —          —          —          50,000        63.11        1,796,500   
    RSU        (7     9/23/2014        —          —          30,000        —          —          1,893,300   
    CBP         N/A          44,308        —          —          —          —     

Anthony G. Quinn

    SO        (5     6/4/2014        —          —          —          45,000        80.35        2,260,800   
    CBP         N/A        —          162,667        —          —          —          —     

Glen Williams

    SO        (5     6/4/2014        —          —          —          45,000        80.35        2,260,800   
    CBP         N/A        —          116,480        —          —          —          —     

 

(1) Type of Award:

SO = Stock Option

CBP = Cash Bonus Plan

RSU= Restricted Stock Unit

(2) The amounts in this column represent the target amounts for incentive bonuses approved by the Board of Directors for each named executive officers in 2014. All awards in these columns were granted under our cash bonus plan. The actual amounts awarded are reported in the “Non-Equity Incentive Plan Compensation” column in the Summary Compensation Table above.
(3) The exercise price of the applicable stock option is equal to the closing price of our common stock as reported by the NASDAQ Global Select Market on the date of grant.
(4) This column represents the grant date fair value of equity awards calculated in accordance with FASB ASC Topic 718. See Note 2 and Note 6 to our audited consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2014 for details as to the assumptions used to determine the fair value of the awards.
(5) These options will vest as to 25% of the total number of shares subject to the option on the first anniversary of the grant date and 1/36th of the remaining shares subject to the option vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(6) These stock options were granted on September 23, 2014. These options will vest as to 25% of the total number of shares subject to the option on the first anniversary of the hire date, September 22, 2014, and 1/36th of the remaining shares subject to the option vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(7) These RSUs will vest as to 25% of the total number of units subject to the award, and the corresponding number of shares will become deliverable, on each anniversary of September 22, 2014, in each case, subject to Mr. Bazemore remaining in Synageva’s employ through the applicable vesting date.

 

19


OUTSTANDING EQUITY AWARDS AT 2014 FISCAL YEAR-END

The following table shows grants of stock options and grants of unvested stock awards outstanding on December 31, 2014, the last day of our fiscal year, to each named executive officer.

 

    Option Awards     Stock Awards  

Name

  Grant Date     Number of
Securities
Underlying
Unexercised
Options (#)
Exercisable
    Number of
Securities
Underlying
Unexercised
Options (#)
Unexercisable
    Option
Exercise
Price ($)
    Option
Expiration
Date
    Number of
Shares or
Units of
Stock that
have not
Vested (#)
    Market Value
of Shares or
Units of
Stock that
Have Not
Vested ($)(12)
 

Sanj K. Patel

    5/25/2011        11,256        11,256 (3)     1.70        5/25/2021        —          —     
    12/20/2011        94,177        41,875 (4)     23.00        12/20/2021        —          —     
    6/27/2012        92,500        55,500 (5)     40.74        6/27/2022        —          —     
    6/6/2013        47,999        80,001 (6)     40.32        6/6/2023        —          —     
    6/4/2014        —          120,000 (9)      80.35        6/4/2014        —          —     

Carsten Boess

    5/25/2011        6,618        16,546 (2)     1.70        5/25/2021        —          —     
    12/20/2011        1,042        6,250 (4)     23.00        12/20/2021        —          —     
    6/27/2012        28,125        16,875 (5)     40.74        6/27/2022        —          —     
    6/6/2013        16,874        28,126 (6)     40.32        6/6/2023        —          —     
    6/4/2014        —          40,000 (9)      80.35        6/4/2014        —          —     

Robert Bazemore

    9/23/2014        —          50,000 (10)      63.11        9/23/2024        30,000 (11)      2,783,700   

Anthony G. Quinn

    10/7/2009        18,964        —   (7)     0.95        10/7/2019        —          —     
    12/15/2009        5,982        —   (1)     0.95        12/15/2019        —          —     
    5/25/2011        42,308        4,920 (3)     1.70        5/25/2021        —          —     
    12/20/2011        17,500        12,500 (4)     23.00        12/20/2021        —          —     
    6/27/2012        28,125        16,875 (5)     40.74        6/27/2022        —          —     
    6/6/2013        16,874       28,126 (6)     40.32        6/6/2023        —          —     
    6/4/2014        —          45,000 (9)      80.35        6/4/2014        —          —     

Glen Williams

    10/4/2012        22,100        17,500 (8)     57.56        10/4/2022        —          —     
    6/6/2013        14,699        25,001 (6)     40.32        6/6/2023        —          —     
    6/4/2014        —          45,000 (9)      80.35        6/4/2014        —          —     

 

(1) These stock options were granted on December 15, 2009 and all options were fully vested as of December 31, 2013.
(2) These stock options were granted on May 25, 2011. These options vested as to 25% of the total number of shares subject to the option on the first anniversary of the hire date and 1/36th of the remaining shares subject to the option vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(3) These stock options were granted on May 25, 2011. These options vested as to 25% of the total number of shares subject to the option on the first anniversary of the grant date and 1/36th of the remaining shares subject to the option vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(4) These stock options were granted on December 20, 2011. These options vested as to 25% of the total number of shares subject to the option on the first anniversary of the grant date and 1/36th of the remaining shares subject to the option vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(5) These stock options were granted on June 27, 2012. These options vested as to 25% of the total number of shares subject to the option on the first anniversary of the grant date and 1/36th of the remaining shares subject to the option will vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.

 

20


(6) These stock options were granted on June 6, 2013. These options vested as to 25% of the total number of shares subject to the option on the first anniversary of the grant date and 1/36th of the remaining shares subject to the option will vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(7) These stock options were granted on October 7, 2009 and all options were fully vested as of December 31, 2013.
(8) These stock options were granted on October 4, 2012. These options vested as to 25% of the total number of shares subject to the option on the first anniversary of the hire date and 1/36th of the remaining shares subject to the option will vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(9) These stock options were granted on June 4, 2014. These options will vest as to 25% of the total number of shares subject to the option on the first anniversary of the hire date and 1/36th of the remaining shares subject to the option will vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(10) These stock options were granted on September 23, 2014. These options will vest as to 25% of the total number of shares subject to the option on the first anniversary of the hire date, September 22, 2014, and 1/36th of the remaining shares subject to the option vest monthly thereafter until all shares are vested. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(11) These RSUs were granted on September 23, 2014. The RSUs will vest as to 25% of the total number of units subject to the award, and the corresponding number of shares will become deliverable, on each anniversary of September 22, 2014. In each case, vesting is subject to the executive remaining in Synageva’s employ through such vesting date.
(12) The market value of the stock awards is determined by multiplying the number of shares by $92.79, the closing price of our common stock on the NASDAQ Global Select Market on December 31, 2014, the last day of our fiscal year.

 

21


OPTION EXERCISES AND STOCK VESTED FOR FISCAL 2014

The following table shows exercises of stock options and restricted stock vesting for the year ended December 31, 2014, for each of the named executive officers.

 

     Option Awards      Stock Awards  

Name

   Number of Shares
Acquired on
Exercise (#)
     Value Realized
on Exercise
($)(1)
     Number of Shares
Acquired on
Vesting
     Value Realized
on Vesting
 

Sanj K. Patel

     152,300         12,677,365         —           —     

Carsten Boess

     45,258         3,593,199         —           —     

Robert Bazemore

     —           —           —           —     

Anthony G. Quinn

     40,000         2,719,089         —           —     

Glen Williams

     700         39,115         —           —     

 

(1) Amounts reflect the difference between the exercise price of the option and the market price at the time of the exercise.

Retirement Benefits

We do not have any pension or qualified or non-qualified defined benefit plans that apply to our named executive officers. We offer a tax-qualified retirement plan (the “401(k) Plan”) to eligible employees. The 401(k) Plan permits eligible employees to defer up to 90% of their annual eligible compensation, subject to certain limitations imposed by the Internal Revenue Code of 1986, as amended (the “Code”). Following a 6-month waiting period for eligibility, the employees’ elective deferrals are immediately vested and non-forfeitable in the 401(k) Plan. In any plan year, we will contribute to each participant a matching contribution equal to 100% of the first 3% of the participant’s compensation that he or she has contributed to the plan and 50% of the next 2% of the participant’s compensation that he or she has contributed to the plan.

Potential Payments Upon Termination or Change of Control

We have entered into certain agreements and maintain certain plans that may require us to make certain payments and/or provide certain benefits to our named executive officers in the event of a termination of employment or a change of control. See “Potential Payments Upon Termination or Change of Control” below for a description of the severance and change in control arrangements for Mr. Patel, Mr. Boess, Mr. Bazemore, Dr. Quinn and Mr. Williams. Each named executive officer would only be eligible to receive severance payments if such officer signed a general release of claims. The following tables summarize the potential payments to each named executive officer assuming that one of the events described in the table occurred. The tables assume that the relevant event occurred on December 31, 2014 and, in calculating the amounts due to the executive in connection with such event, use the closing price of a share of our common stock, $92.79, on such date, and that all outstanding equity awards were assumed, substituted, or cashed out in the change of control. However, the executive’s employment was not terminated on December 31, 2014 under such agreement and a change in control did not occur on that date. There can be no assurance that a termination of employment, a change in control or both would produce the same or similar results as those set forth below if either or both of them occur

 

22


on any other date or at any other price, or if any other assumption used in calculating the benefits set forth below is not correct in fact.

 

Name and Event

   Cash
Severance
Payments ($)
    Acceleration of
time-vesting
Equity Awards ($)(1)
     Health and
Welfare ($)
     Exercise
Tax
Gross Up ($)
     Total
Termination
Benefits ($)
 

  Sanj K. Patel

             

•    Death

     1,539,822 (2)     10,101,435         —          —          11,641,258   

•    Disability

     1,539,822 (2)     10,101,435         —          —          11,641,258   

•    Involuntary termination other than for cause

     1,539,822 (2)     10,101,435         —          —          11,641,258   

•    Involuntary termination after a change in control

     2,044,763 (3)     12,526,993         —          —          14,571,756   

Name and Event

   Cash
Severance
Payments ($)
    Acceleration of
time-vesting
Equity Awards ($)(1)
     Health and
Welfare ($)
     Exercise
Tax
Gross Up ($)
     Total
Termination
Benefits ($)
 

  Carsten Boess

             

•    Death

     281,190 (4)     3,305,800         —          —          3,586,990   

•    Disability

     281,190 (4)     3,305,800         —          —          3,586,990   

•    Involuntary termination other than for cause

     281,190 (4)     3,305,800         —          —          3,586,990   

•    Involuntary termination after a change in control

     391,420 (5)     4,795,078         —          —          5,186,498   

Name and Event

   Cash
Severance
Payments ($)
    Acceleration of
time-vesting
Equity Awards ($)(1)
     Health and
Welfare ($)
     Exercise
Tax
Gross Up ($)
     Total
Termination
Benefits ($)
 

  Robert Bazemore

             

•    Death

     480,000 (6)     1,159,675         —          —          1,639,675   

•    Disability

     480,000 (6)     1,159,675         —          —          1,639,675   

•    Involuntary termination other than for cause

     480,000 (6)     1,159,675         —          —          1,639,675   

•    Involuntary termination after a change in control

     496,500 (5)     4,267,700         —          —          4,674,200   

Name and Event

   Cash
Severance
Payments ($)
    Acceleration of
time-vesting
Equity Awards ($)(1)
     Health and
Welfare ($)
     Exercise
Tax
Gross Up ($)
     Total
Termination
Benefits ($)
 

  Anthony G. Quinn

             

•    Death

     406,668 (6)     2,706,300         —          —          3,112,968   

•    Disability

     406,668 (6)     2,706,300         —          —          3,112,968   

•    Involuntary termination other than for cause

     406,668 (6)     2,706,300         —          —          3,112,968   

•    Involuntary termination after a change in control

     423,168 (5)     4,234,453         —          —          4,657,621   

Name and Event

   Cash
Severance
Payments ($)
    Acceleration of
time-vesting
Equity Awards ($)(1)
     Health and
Welfare ($)
     Exercise
Tax
Gross Up ($)
     Total
Termination
Benefits ($)
 

  Glen Williams

             

•    Death

     249,600 (4)     1,086,913         —          —          1,336,513   

•    Disability

     249,600 (4)     1,086,913         —          —          1,336,513   

•    Involuntary termination other than for cause

     249,600 (4)     1,086,913         —          —          1,336,513   

•    Involuntary termination after a change in control

     349,300 (5)     2,488,127         —          —          2,837,427   

 

23


 

(1) Represents the pre-tax cash-out value of all stock options and RSUs that would accelerate as a result of the event described in the table, based on a stock price of $92.79, which was the closing price of Synageva’s common stock on December 31, 2014. Amounts are based on the number of shares associated with each accelerated option multiplied by the difference between $92.79 and the exercise price of such option.
(2) Represents the sum of (i) 18 months of base salary and 1.5 x annual target bonus as in effect on December 31, 2014 and (ii) a one-time bonus of $25,000, all of which would be paid in a lump sum. The executive is also entitled to receive a lump-sum pro rata bonus for the year of termination, the amount of which is not included in the table because the full 2014 bonus had been earned by the executive on December 31, 2014, without regard to his employment termination.
(3) Represents the sum of (i) 24 months of base salary and 2 x annual target bonus as in effect on December 31, 2014 and (ii) a one-time bonus of $25,000, all of which would be paid in a lump sum. The executive is also entitled to receive a lump-sum pro rata bonus for the year of termination, the amount of which is not included in the table because the full 2014 bonus had been earned by the executive on December 31, 2014, without regard to his employment termination.
(4) Represents 9 months of base salary as in effect on December 31, 2014 that would be paid in a lump sum. The executive is also entitled to receive a lump-sum pro rata bonus for the year of termination, the amount of which is not included in the table because the full 2014 bonus had been earned by the executive on December 31, 2014, without regard to his employment termination.
(5) Represents the sum of (i) 12 months of base salary as in effect on December 31, 2014 and (ii) a one-time bonus of $16,500, both of which would be paid in a lump sum. The executive is also entitled to receive a lump-sum bonus, equal to his annual target bonus, for the year of termination. This amount is not included in the table because the full 2014 bonus had been earned by the executive on December 31, 2014, without regard to his employment termination.
(6) Represents 12 months of base salary as in effect on December 31, 2014. The executive is also entitled to receive a lump-sum pro rata bonus for the year of termination, the amount of which is not included in the table because the full 2014 bonus had been earned by the executive on December 31, 2014, without regard to his employment termination.

Securities Authorized for Issuance Under Equity Compensation Plans

The following table sets forth information about our equity compensation plans as of December 31, 2014, including the number of shares of our common stock issuable upon exercise of all outstanding options, the weighted-average exercise price of all outstanding options and the number of shares available for future issuance under our equity compensation plans.

 

Plan Category

   (a)
Number of
securities to be
issued upon
exercise
of outstanding
options,
warrants and rights
     (b)
Weighted-
average
exercise price of
outstanding
options,
warrants and
rights
     (c)
Number of
securities
remaining
available for
future issuance
under equity
compensation
plans (excluding
securities
reflected in
column (a))
 

Equity Compensation Plans Approved by Stockholders

     3,286,000       $ 53.71         1,365,000   

Equity Compensation Plans Not Approved by Stockholders

     —          —          —    

 

24


DIRECTOR COMPENSATION FOR FISCAL 2014

The following table sets forth cash compensation and the value of stock options awards granted to our non-management directors for their service in 2014.

 

Name

   Fees Earned
or Paid in
Cash
($)(1)
     Option
Awards
($)(2)(3)
     All Other
Compensation
($)
     Total
($)
 

Felix J. Baker, Ph.D.

     50,000         376,800         —          426,800   

Stephen R. Biggar, M.D., Ph.D.

     28,000         376,800         —          404,800   

Stephen R. Davis

     34,000         376,800         —          410,800   

Thomas R. Malley

     43,000         376,800         —          419,800   

Barry Quart, Pharm.D.

     25,000         376,800         —          401,800   

Thomas J. Tisch

     25,000         376,800         —          401,800   

Peter Wirth

     34,000         376,800         —          410,800   

 

(1) Represents retainer fees paid for services as a director during the fiscal year ended December 31, 2014.
(2) See Note 2 and Note 6 to our audited consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2014 for details as to the assumptions used to determine the fair value of the awards during the year ended December 31, 2014.
(3) Represents the grant date fair value of the award calculated in accordance with FASB ASC Topic 718. The following directors held the following number of stock option awards as of December 31, 2014: Dr. Baker, 53,350; Dr. Biggar, 37,500; Mr. Davis, 53,500; Mr. Malley, 44,926; Dr. Quart, 29,876; Mr. Tisch, 30,000; Mr. Wirth, 30,000.

Director Compensation

We reimburse our directors for all reasonable and necessary travel and other incidental expenses incurred in connection with their attendance at meetings of the Board of Directors. Management directors do not receive additional compensation in connection with their board service or attendance at meetings. In December 2011, our Board of Directors adopted the following policy for compensation of the non-management members of our Board:

 

Non-Management Chairman Annual Retainer

   $ 35,000   

Non-Management Directors’ Annual Retainer

   $ 25,000   

Committee Member’s Additional Annual Fees

  

Audit Committee Chairman

   $ 15,000   

Audit Committee Member

   $ 5,000   

Compensation Committee Chairman

   $ 10,000   

Compensation Committee Member

   $ 4,000   

Nomination and Governance Committee Chairman

   $ 5,000   

Nomination and Governance Committee Member

   $ 3,000   

Non-Management Directors’ Stock Options

  

Director Initial Grant

     15,000   

Director Annual Grant

     7,500   

Initial stock option awards vest monthly over the three years following the grant date, subject to such director’s continued service on the board of directors. Annual stock option awards to non-management directors vest monthly over the year following the grant date, subject to the non-employee director’s continued service on the board of directors.

 

25


Certain Relationships and Related Party Transactions

The Company and the Baker Bros. Advisors, LP, of which Dr. Baker is a Co-Managing Member and Dr. Biggar is a Partner, entered into a letter agreement in March 2014 under which the parties agreed to negotiate in good faith the terms of a registration rights agreement for the registration of the securities of the Company owned by affiliates of the Baker Bros. Advisors, LP and Drs. Baker and Biggar. The Company then amended its existing Registration Rights Agreement and entered into a new Registration Rights Agreement with certain of its stockholders, including affiliates of the Baker Bros. Advisors, LP and Drs. Baker and Biggar, as well as Mr. Tisch and his affiliates. The Audit Committee reviewed and approved the arrangement and related transactions described above consistent with the process described in the following paragraph.

The Audit Committee, as outlined in our Audit Committee Charter, reviews and approves transactions between us and a related party, such as our directors, officers, holders of more than 5% of our voting securities and their affiliates, the immediate family members of any of the foregoing persons and any other persons whom the Board of Directors determined may be considered a related party. Prior to Audit Committee consideration of a transaction with a related party, the material facts as to the related party’s relationship or interest in the transaction are disclosed to the Audit Committee, and the transaction is not considered approved by the Audit Committee unless a majority of the directors who are not interested in the transaction approve the transaction. In determining whether to approve or ratify a related party transaction, the non-interested directors take into account such factors as they deem appropriate, which include whether the interested transaction is on terms no less favorable than terms generally available to an unaffiliated third party under the same or similar circumstances and the extent of the related person’s interest in the transaction. Please see “Executive Compensation—Summary Compensation Table,” “Executive Compensation—Director Compensation” for information regarding compensation of our executive officers and directors.

 

26



Exhibit (e)(10)

Amendment No. 1 to the Synageva BioPharma Corp.

Employee Stock Purchase Plan

WHEREAS, Synageva BioPharma Corp. (the “Company”) has adopted and maintains the Synageva BioPharma Corp. Employee Stock Purchase Plan (the “Plan”); and

WHEREAS, the Board of Directors of the Company desires to amend the Plan as set forth herein.

NOW, THEREFORE, pursuant to Section 18 of the Plan, the Plan is hereby amended as follows:

1. The following new Section 19 is hereby added to read in its entirety as follows:

SECTION 19. Suspension of Plan

Effective as of May 5, 2015, no Eligible Employee may elect to participate in the Plan and no Participant may increase their payroll deduction. In addition, the outstanding Option Period scheduled to end on June 30, 2015 will terminate at the earlier of (x) June 30, 2015 and (y) the date that is 7 business days prior to the Applicable Time (as defined in the Agreement), and be the final Option Period under the Plan, and the accumulated contributions of each Participant will be used to purchase shares of Stock determined under Section 6 on the earlier of (x) June 30, 2015 and (y) the date that is 7 business days prior to the Applicable Time (with any Participant payroll deductions not applied to the purchase of shares returned to the Participant). For purposes of this Section 19, “Agreement” means the Agreement and Plan of Reorganization by and among Alexion Pharmaceuticals Inc., Pulsar Merger Sub Inc., Galaxy Merger Sub LLC and the Employer, dated as of May 5, 2015. Notwithstanding anything to the contrary, if the Agreement terminates without consummation of the transactions contemplated thereunder, the Plan shall resume in accordance with its terms with respect to the first Option Period commencing after the date on which the Agreement is terminated, without regard to this Section 19.

In all other respects, the Plan shall remain in full force and effect in accordance with its terms.

As adopted by the Board of Directors of Synageva Biopharma Corp. on May 5, 2015.

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