By Maria Armental 
 

AbbVie Inc. (ABBV) on Friday said it is again extending its exchange offer to buy cancer biotech Pharmacyclics Inc. (PCYC) in a cash-and-stock deal valued at $21 billion.

The pharmaceutical giant, which last year called off a deal to buy Dublin's Shire PLC after new U.S. tax rules made it harder for American companies to lower taxes through deal-making abroad, refiled its application with the Federal Trade Commission following its first extension on April 17.

The first extended offer would have expired at 5 p.m. EDT Friday. Under the new extension, the offer is set to expire on May 15 at 5 p.m.

The deal would give AbbVie a presence in the multibillion-dollar blood-cancer market and lessen its reliance on Humira, a rheumatoid-arthritis therapy that in 2014 accounted for $12.5 billion in sales, or more than 60% of the company's total.

Write to Maria Armental at maria.armental@wsj.com

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