FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

OMB APPROVAL
OMB Number: 3235-0104
Estimated average burden
hours per response... 0.5
                      
Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Casdin Capital, LLC		 2. Date of Event Requiring Statement (MM/DD/YYYY)
1/31/2023 

 3. Issuer Name and Ticker or Trading Symbol

GeneDx Holdings Corp. [WGS]
(Last)        (First)        (Middle)

1350 AVENUE OF THE AMERICAS, SUITE 2600		 4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                          ___X___ 10% Owner
_____ Officer (give title below)        _____ Other (specify below)
(Street)

NEW YORK, NY 10019      

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
 

6. Individual or Joint/Group Filing(Check Applicable Line)

___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		2. Amount of Securities Beneficially Owned
(Instr. 4)		3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Class A Common Stock 87866042 I See Footnote (1)
Class A Common Stock 14285743 I See Footnote (2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)		2. Date Exercisable and Expiration Date
(MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		4. Conversion or Exercise Price of Derivative Security5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
(1) The 87,866,042 shares of Class A common stock reported in the table above are owned directly by Casdin Partners Master Fund, LP and may be deemed to be indirectly beneficially owned by (i) Casdin Capital, LLC, the investment adviser to Casdin Partners Master Fund, LP, (ii) Casdin Partners GP, LLC, the general partner of Casdin Partners Master Fund LP, and (iii) Mr. Casdin, the managing member of Casdin Capital, LLC and Casdin Partners GP, LLC. Each of Casdin Capital, LLC, Casdin Partners GP, LLC and Mr. Casdin disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein.
(2) The 14,285,743 shares of Class A common stock reported in the table above are owned directly by Casdin Partners FO1-MSV, LP and may be deemed to be indirectly beneficially owned by (i) Casdin Capital, LLC, the investment adviser to Casdin Partners FO1-MSV, LP, (ii) Casdin Partners GP, LLC, the general partner of Casdin Partners FO1-MSV, LP, and (iii) Mr. Casdin, the managing member of Casdin Capital, LLC and Casdin Partners GP, LLC. Each of Casdin Capital, LLC, Casdin Partners GP, LLC and Mr. Casdin disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Casdin Capital, LLC
1350 AVENUE OF THE AMERICAS
SUITE 2600
NEW YORK, NY 10019		XX

Casdin Partners GP, LLC
1350 AVENUE OF THE AMERICAS
SUITE 2600
NEW YORK, NY 10019		XX

Casdin Partners Master Fund, L.P.
1350 AVENUE OF THE AMERICAS
SUITE 2600
NEW YORK, NY 10019		XX

Casdin Partners FO1-MSV, LP
1350 AVENUE OF THE AMERICAS
SUITE 2600
NEW YORK, NY 10019		XX
Signatures
CASDIN CAPITAL, LLC, Name: /s/ Eli Casdin, Title: Managing Member2/10/2023
**Signature of Reporting PersonDate

CASDIN PARTNERS GP, LLC, Name: /s/ Eli Casdin, Title: Managing Member2/10/2023
**Signature of Reporting PersonDate

CASDIN PARTNERS MASTER FUND, LP, By: Casdin Partners GP, LLC, Its: General Partner, Name: /s/ Eli Casdin, Title: Managing Member2/10/2023
**Signature of Reporting PersonDate

CASDIN PARTNERS FO1-MSV, LP, By: Casdin Partners GP, LLC, Its: General Partner, Name: /s/ Eli Casdin, Title: Managing Member2/10/2023
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
Sema4 (NASDAQ:SMFR)
Gráfico Histórico do Ativo
De Abr 2024 até Mai 2024 Click aqui para mais gráficos Sema4.
Sema4 (NASDAQ:SMFR)
Gráfico Histórico do Ativo
De Mai 2023 até Mai 2024 Click aqui para mais gráficos Sema4.