LEO Pharma and MorphoSys Expand Strategic Alliance to Develop Peptide-derived Therapeutics
18 Setembro 2018 - 4:52AM
Business Wire
LEO Pharma A/S, a global leader in medical dermatology, and
MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX; NASDAQ:
MOR) today announced an expansion of their existing strategic
alliance to include peptide-derived therapeutics. The objective of
the alliance is to identify novel, peptide-derived therapeutics for
unmet medical needs that will be valuable additions to both
companies’ pipelines. This alliance expands the existing
partnership of the two companies signed in November 2016 to jointly
discover and develop antibody-based therapies in dermatology.
Under the terms of the agreement, LEO Pharma will select targets
against which MorphoSys will identify lead molecules using its
proprietary peptide technology platform. LEO Pharma will either
develop these lead molecules, or use them to aid the design of
other drug candidates. LEO Pharma will have exclusive, worldwide
rights and be responsible for development and commercialization of
resulting drugs in dermatology. MorphoSys will have an exclusive
option to secure worldwide rights to any drugs arising from the
collaboration in the field of oncology.
“It is with great pleasure that we expand our collaboration with
MorphoSys to also include identification of lead molecules for
selected targets of particular dermatological interest,” said
Thorsten Thormann, Vice President, Research, LEO Pharma. “By
continuing our innovative collaboration to find and develop novel,
peptide-derived therapeutics we will boost our pipeline while
committing to even greater efforts in our quest to address the high
unmet medical needs among people with skin diseases.”
MorphoSys will receive R&D funding as well as success-based
development, regulatory and commercial milestone payments, plus
royalties on net sales of peptide drugs commercialized by LEO
Pharma. Further financial details were not disclosed.
“We are excited to expand our existing antibody partnership with
LEO Pharma with the goal of developing novel, peptide-derived
drugs,” said Dr. Markus Enzelberger, Chief Scientific Officer of
MorphoSys AG. “This partnering deal utilizes our newest innovative
proprietary peptide technology and creates an ideal route for
differentiated product candidates in an area of severe unmet
medical need.”
About MorphoSys’s peptide
technology
MorphoSys’s peptide technology aims at generating a novel class
of structured and eminently stable peptides enabling highly
selective and high affinity target binding. Potential applications
of peptides include the use as stand-alone drugs, as fusion
partners to proteins, or as agents that are chemically modified or
fused to toxins. This approach is intended to enable targeting of
novel epitopes and to open up new target space.
About MorphoSys:
MorphoSys is a late-stage, biopharmaceutical company devoted to
the development of innovative and differentiated therapies for
patients suffering from serious diseases. Based on its
technological leadership in generating antibodies, MorphoSys,
together with its partners, has developed and contributed to the
development of more than 100 product candidates, of which 29 are
currently in clinical development. This broad pipeline spans
MorphoSys’s two business segments: Proprietary Development, in
which MorphoSys invests in product candidates for its own account,
and Partnered Discovery, in which product candidates are developed
exclusively for a variety of Pharma and Biotech partners. In 2017,
Tremfya® (guselkumab), marketed by Janssen, became the first
therapeutic antibody based on MorphoSys’s proprietary technology to
receive marketing approval for the treatment of moderate to severe
plaque psoriasis in the United States, the European Union and
Canada. MorphoSys is listed on the Frankfurt Stock Exchange and on
the U.S. stock exchange Nasdaq under the symbol MOR. For regular
updates about MorphoSys, visit https://www.morphosys.com.
HuCAL®, HuCAL GOLD®, HuCAL PLATINUM®, CysDisplay®, RapMAT®,
arYla®, Ylanthia®, 100 billion high potentials®, Slonomics®,
Lanthio Pharma® and LanthioPep® are registered trademarks of the
MorphoSys Group. Tremfya® is a trademark of Janssen Biotech.
About LEO Pharma
LEO Pharma helps people achieve healthy skin. By offering care
solutions to patients in more than 130 countries globally, LEO
Pharma supports people in managing their skin conditions. Founded
in 1908 and owned by the LEO Foundation, the healthcare company
headquartered in Denmark has devoted decades of research and
development to delivering products and solutions to people with
skin conditions. In 2017 LEO Pharma employed around 5,200 people
worldwide and had sales of 1.4 billion euros. For more information,
visit www.leo-pharma.com and
www.linkedin.com/company/leo-pharma
This communication contains certain forward-looking statements
concerning the MorphoSys group of companies, including expectations
regarding the strategic alliance with LEO Pharma A/S to identify
and develop new peptide-based therapeutics for skin diseases,
MorphoSys’s peptide technology and expectations regarding potential
success-based development, regulatory and commercial milestone
payments, plus potential royalties on net sales of peptide drugs
commercialized by LEO Pharma. The forward-looking statements
contained herein represent the judgment of MorphoSys as of the date
of this release and involve known and unknown risks and
uncertainties, which might cause the actual results, financial
condition and liquidity, performance or achievements of MorphoSys,
or industry results, to be materially different from any historic
or future results, financial conditions and liquidity, performance
or achievements expressed or implied by such forward-looking
statements. In addition, even if MorphoSys' results, performance,
financial condition and liquidity, and the development of the
industry in which it operates are consistent with such
forward-looking statements, they may not be predictive of results
or developments in future periods. Among the factors that may
result in differences are that MorphoSys's expectations regarding
the strategic alliance with LEO Pharma to identify and develop new
peptide-based therapeutics for skin disease, MorphoSys’s peptide
technology and expectations regarding potential success-based
development, regulatory and commercial milestone payments, plus
potential royalties on net sales of peptide drugs commercialized by
LEO Pharma are false MorphoSys's reliance on collaborations with
third parties, estimating the commercial potential of its
development programs and other risks indicated in the risk factors
included in MorphoSys’s Registration Statement on Form F-1 and
other filings with the US Securities and Exchange Commission. Given
these uncertainties, the reader is advised not to place any undue
reliance on such forward-looking statements. These forward-looking
statements speak only as of the date of publication of this
document. MorphoSys expressly disclaims any obligation to update
any such forward-looking statements in this document to reflect any
change in its expectations with regard thereto or any change in
events, conditions or circumstances on which any such statement is
based or that may affect the likelihood that actual results will
differ from those set forth in the forward-looking statements,
unless specifically required by law or regulation.
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MorphoSys AGAlexandra
GollerAssociate Director Corporate Communications & IRJochen
OrlowskiAssociate Director Corporate Communications & IRDr.
Claudia Gutjahr-L�serInvestor Relations OfficerTel: +49 (0) 89 /
899 27-404investors@morphosys.comorLEO Pharma A/SHenrik KyndlevHead of Global
External CommunicationTel: +45 3140
6180Henrik.kyndlev@leo-pharma.comorMaia Fredtoft
SoechtingCorporate Communications ManagerTel: +45
31193559mfddk@leo-pharma.com
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