• Patented technology used to assist patients in optimizing their drug dosage through intelligent and adaptive algorithms
  • Expansion of Voluntis' existing intellectual property portfolio in the field of digital therapeutics
  • Application in the field of diabetes for insulin titration support

Regulatory News:

Voluntis (Paris:VTX) (Euronext Paris, Ticker: VTX - ISIN: FR0004183960), a leader in digital therapeutics, announced today the issuance of a new patent by the European Patent Office (EPO) for intelligent patient support in drug dosing applied in the field of diabetes for insulin titration support.

Following the prescription of the drug and its companion digital therapeutic, the intelligent and adaptive algorithms developed by Voluntis will automatically recommend to a patient, day by day and according to the evolution of their monitoring data, a progressive increase of the dose to bring the patient into the target range as specified by their physician. Safety mechanisms are also present to decrease the dose if the situation requires it. Once the target range is reached, the dose will then remain stable as long as the patient's follow-up data stays within the target range.

In the field of diabetes, the patent obtained relates to the optimization of insulin titration, based on the evolution of fasting blood glucose levels over several days to recommend to the patient an appropriate dose of basal insulin to be injected, in accordance with their treatment plan. More specifically, this new patent covers the management of the sensitivity of the titration algorithms to changes in the patient's blood glucose levels to optimize the achievement and maintenance of the dose enabling glycemic control.

"Thanks to this patented technology, we are extending the scope of cutting-edge solutions available to our clinical and industrial partners wishing to offer unique treatment experiences to patients worldwide" said Pierre Leurent, Chief Executive Officer. "Successfully dosing drug treatments, particularly in the context of complex therapies, is often a challenge for patients and their healthcare teams, Digital therapeutics now provide innovative solutions thanks to embedded algorithms that provide patients with daily and personalized recommendations, in compliance with the physician's prescription and with performance and safety standards. ".

"We are proud to obtain this new patent, which builds on Voluntis' 15 years of experience in the field of dosage support with digital therapeutics" added Etienne Vial, Chief Technology Officer. "Our Theraxium platform is already being used for drug dosing support in therapeutic areas other than diabetes, particularly in oncology for the dosing of symptomatic treatments. These developments in our platform offer promise to further extend our approach to other therapeutic areas. »

About Voluntis

Voluntis creates digital therapeutics that empower people with chronic conditions to self-manage their treatment every day, thus improving real-world outcomes. Voluntis’ solutions, combining mobile and web apps, use clinical algorithms to deliver personalized recommendations to patients and their care teams. For example, these recommendations are used to adjust treatment dosage, manage side effects or monitor symptoms.

Leveraging its Theraxium technology platform, Voluntis has designed and operates multiple digital therapeutics, especially in oncology and diabetes. Voluntis has long-standing partnerships with leading life science companies. Based in Cambridge, MA, and Paris, France, Voluntis is a founding member of the Digital Therapeutics Alliance.

For more information, please visit: www.voluntis.com

Mnemo : VTX - ISIN : FR0004183960

Disclaimer

This press release contains certain forward-looking statements concerning Voluntis group and its business, including its prospects and product candidate development. Such forward-looking statements are based on assumptions that Voluntis considers to be reasonable. However, there can be no assurance that the estimates contained in such forward-looking statements will be verified, which estimates are subject to numerous risks including the risks set forth in the 2019 annual financial report and the 2020 half-year financial report published by Voluntis respectively on April 30, 2020 and September 29, 2020 (a copy of which is available on www.voluntis.com) and to the development of economic conditions, financial markets and the markets in which Voluntis operates. The forward-looking statements contained in this press release are also subject to risks not yet known to Voluntis or not currently considered material by Voluntis. The occurrence of all or part of such risks could cause actual results, financial conditions, performance or achievements of Voluntis to be materially different from such forward-looking statements. Voluntis expressly declines any obligation to update such forward-looking statements.

ACTUS Media relations Vivien Ferran vferran@actus.fr +33 (0)1 53 67 36 34

ACTUS Investor relations Jérôme Fabreguettes-Leib voluntis@actus.fr +33 (0)1 53 67 36 78

Voluntis Chief Financial Officer Guillaume Floch investisseurs@voluntis.com +33 (0)1 41 38 39 20

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