May 29, 2019: 

NanoSphere Health Sciences Inc. (CSE: NSHS) (OTC: NSHSF) CEO Robert Sutton today congratulated the Governor and Legislature of Colorado for their passage of an historic bill allowing physicians to recommend cannabis instead of opioids for relief of pain. 

“Colorado is the first state in the US, and among very few governments around the world, that has recognized the potential of cannabis to deal with chronic or acute pain,” said Sutton. “This is a courageous and critical first step in battling the epidemic of opioid deaths we have suffered in the United States.”

Colorado Governor Jared Polis signed Senate Bill 13 on Thursday as the State wrestles with the growing problem of opioid addiction. Currently physicians can prescribe medical marijuana for patients suffering from cancer, glaucoma, HIV and AIDS, PTSD, or other chronic disorders that cause severe pain, seizures and nausea.

When the law takes effect on Aug. 2 this year, physicians will have the option of prescribing cannabis for any medical condition for which opioids are currently prescribed. 

“The state government is not telling doctors they have to replace opioids with cannabis, but rather, they are endorsing the idea that doctors should be given the latitude to use cannabis for treatment, rather than opting for opioids, which are much more addictive and much more likely to result in a fatal overdose,” explained NanoSphere Chief Science Officer Richard Kaufman. 

“This falls in line with all of our own research, much of which has been in the area of replacing opioids with cannabinoids for the treatment of severe and chronic pain.”

NanoSphere’s patented lipid nanoparticles efficiently encapsulate and effectively delivery therapeutic dosages of full spectrum cannabis oil extracts for relieving acute, chronic and neurogenic pain and inflammation through different routes of administration. They include transdermal, intranasal and intraoral delivered Nanosphere products. NanoSphere’s transdermal NanoSerum is currently sold through a network of dispensaries in Colorado and California. 

“We have already seen significant results with our transdermal NanoSerum in clinical observations of patients with very severe, acute pain, and some people have stopped using opioids and have replaced them with our product, which is not addictive, and is free of any serious side effects,” said Kaufman. “What has been missing to date is the endorsement of government and the medical community that cannabinoids can, in fact, act as a viable alternative to opioids.”

Kaufman points out there is a large and growing body of evidence that medical cannabis can act as a substitute or an adjunct to prescription opiates in the treatment of chronic and acute pain.

A recent study in the Clinical Journal of Pain followed 176 patients with chronic pain in Israel, and found that 44 per cent of them stopped taking prescription opioids within seven months of starting use of medical cannabis. Patients cited several reasons for preferring cannabis over prescription drugs, with 65 per cent reporting fewer adverse side effects, 57 per cent citing better management of symptoms, and 34 per cent saying cannabis had far less potential for withdrawal issues. (Haroutounian S, et al: The Effect of Medicinal Cannabis on Pain and Quality-of-Life Outcomes in Chronic Pain: A Prospective Open-label Study. Clin J Pain. 2016 Dec;32(12):1036-1043)

“No one is claiming that cannabis can treat everything, or that it’s the right choice for every person suffering from severe pain, but what we believe and what the Colorado government has endorsed, is that proper application of medical cannabis can help reduce our society’s reliance on more addictive, more dangerous medicines,” said Sutton. “Colorado has taken an historic step forward, and we expect to be part of the solution as doctors and patients explore healthier alternatives to opioid=based therapies.”

On behalf of the Board

David Sutton, President and COO

720.520.4283

dsutton@nanospherehealth.com

Investor Contact:

Victor Goncalves, Executive Vice President

Mobile: 204-997-5517

E-mail: vgoncalves@nanospherehealth.com

About NanoSphere

NanoSphere Health Sciences LLC, is a biotechnology firm specializing in the creation of the NanoSphere Delivery System™, a revolutionary platform using nanotechnology in the biodelivery of supplements, nutraceuticals and over-the-counter medications for the cannabis, pharmaceutical and animal health industries, and beyond. For more information on NanoSphere, please visit http://www.nanospherehealth.com.

About Evolve Formulas

Evolve Formulas is the provider of the world's first and only scientifically proven nanoparticle delivery system in cannabis. Evolve’s pioneering product, Transdermal NanoSerum™, is a fast-acting, ultra-strength transdermal formula infused with nano-encapsulated cannabis and cannabis extracts. For more information on Evolve Formulas, visit https://www.evolveformulas.com/. Follow us on Facebook, Instagram and Twitter.

The Canadian Securities Exchange does not accept responsibility for the adequacy or accuracy of this release.

Forward Looking Statement Caution

This news release includes forward looking statements that are subject to assumptions, risks and uncertainties. Statements in this news release which are not purely historical are forward looking statements, including without limitation any statements concerning the Company's intentions, plans, estimates, expectations or beliefs regarding the future. Although the Company believes that any forward looking statements in this news release are reasonable, there can be no assurance that any such forward looking statements will prove to be accurate. The Company cautions readers that all forward looking statements, including without limitation those relating to the Company's future operations and business prospects, are based on assumptions none of which can be assured, and are subject to certain risks and uncertainties that could cause actual events or results to differ materially from those indicated in the forward looking statements. Without limitation, these include assumptions, risks and uncertainties inherent in completing sub-licensing arrangements in the United States, Canada and abroad, product demand, production, competition and government regulation of the Cannabis industry, any and all of which may have an adverse effect on the Company’s expansion plans, sales, revenues and its financial results and condition.  Readers are advised to rely on their own evaluation of such risks and uncertainties and should not place undue reliance on forward looking statements. Any forward looking statements are made as of the date of this news release, and the Company assumes no obligation to update the forward looking statements, or to update the reasons why actual events or results could or do differ from those projected in the forward looking statements, whether as a result of new information, future events or otherwise. 

Kate Wells
NanoSphere Health Sciences
(303) 324-7358
kwells@nanospherehealth.com
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