Ambrilia Biopharma Inc. (TSX:AMB) today reported positive 24-week extension
Phase III ("Study 302") top line results for its proprietary prolonged-release
formulation of octreotide C2L. Overall, the results support the safety of C2L
over an additional period of 6 months. In addition, the efficacy as measured by
the mean Insulin-like Growth Factor 1 ("IGF-1") and Growth Hormone ("GH") plasma
levels is maintained at the same level throughout the study period. It further
confirms that octreotide C2L 30 mg every 6 weeks can replace Sandostatin(R)LAR
30 mg every 4 weeks in acromegalic patients, with the same clinical benefit and
no unexpected or serious adverse effects.


"These new data further validate C2L's potential to be a safe, effective and
cost effective therapy, well positioned to capture a sizeable portion of the $1
billion-plus Sandostatin(R)LAR market," said Dr. Philippe Calais, President and
Chief Executive Officer of Ambrilia. "Again, we are progressing well toward our
year-end divestment goal for C2L which could alleviate the Company's financial
overhang by bringing non-dilutive funding."


Study 302 Top Line Results

This open label 24-week extension study evaluated the safety, clinical and
biological activity of C2L 30 mg in acromegalic patients. Study 302 follows
Study 301, a 24-week comparative clinical trial against Sandostatin(R)LAR
("SLAR") for which results were reported by the Company on May 14, 2008.
Patients receiving SLAR for the first 84 days (12 weeks) in Study 301 received
C2L for 9 additional months (36 weeks). Patients initially randomized on C2L
received C2L for nearly a year.


Mean efficacy on IGF-1 was identical, throughout Study 302, to what it was after
84 days (12 weeks) of treatment in the first part of Study 301 with either C2L
or SLAR. This suggests that switching from SLAR every 4 weeks to C2L every 6
weeks does not induce a decrease in IGF-1 response, even after 36 additional
weeks follow-up. Efficacy on GH was also maintained throughout Study 302, again
supporting that switching from SLAR every 4 weeks to C2L every 6 weeks at the
same dose yields the same efficacy on GH control in acromegalics over an
extended period of time.


The number of patients with normalized IGF-1 and/or GH levels was identical or
slightly higher (though not significantly) after treatment with C2L as compared
to SLAR.


No patient dropped out from Study 302 (all 63 patients completed the study). No
serious adverse event occurred during the 24 weeks of Study 302, during which
all patients were on C2L.


Overall, the top-line analysis of the results supports the ability of C2L 30 mg
given every 6 weeks to replace Sandostatin LAR(R) given every 4 weeks at the
same dose, with mean efficacy and safety maintained over an additional 6 months
treatment.


The Company expects regulatory filings to be initiated before the end of 2008.

About Acromegaly and Octreotide C2L

Acromegaly is a rare and serious condition related to the hypersecretion of
growth hormone by the pituitary gland, generally of tumoral origin. This causes
an uncontrolled growth of organs, debilitating symptoms and a shorter life
expectancy. Pharmacotherapy with somatostatin analogs is one of the treatment
options, a life-long treatment with a few and mild side effects. Novartis'
Sandostatin(R) (octreotide) is the market leader and which efficacy is clearly
established for treating acromegaly. The yearly treatment with the long-acting
release (LAR) formulation of the product, which consists of intramuscular
injections every 4 weeks, is costly. Difficult reconstitution prior to injection
is also an issue.


Ambrilia has developed an improved, proprietary prolonged release formulation of
Octreotide (C2L) for which Phase III results have indicated its ability to
replace Sandostatin LAR(R) with less frequent injections and non inferior
efficacy, and comparable safety. C2L is easier to reconstitute and could be the
first therapeutic alternative to Sandostatin(R)LAR.


AMBRILIA'S FORWARD-LOOKING STATEMENTS

This press release contains forward-looking statements that reflect the
Company's current expectation regarding future events. There is a risk that
expectations and forward looking statements will not prove to be accurate.
Readers are cautioned not to place undue reliance on these forward-looking
statements as they involve risks and uncertainties, which could make actual
results differ materially from those projected herein and depend on a number of
factors including, but not limited to, changing market conditions, successful
and timely completion of clinical studies, uncertainties related to the
regulatory approval process, establishment of corporate alliances and other
risks detailed from time to time in the Company's filings. We refer you to the
Risk Factors section of the Company's annual information form which contains a
more exhaustive analysis of the risks and uncertainties that are generally
connected to the business of the Company. Such statements are also based on
various assumptions, including the successful and timely completion of clinical
studies on Ambrilia's products demonstrating efficacy and safety for human use,
their successful commercialization within the forecasted timelines and the
attainment of the forecasted milestone payments and other revenues. While
Ambrilia anticipates that subsequent events and developments may cause
Ambrilia's views to change, Ambrilia specifically disclaims any obligation to
update these forward looking statements, unless obligated to do so by applicable
securities laws.


ABOUT AMBRILIA BIOPHARMA

Ambrilia Biopharma Inc. (TSX:AMB) is a biotechnology company focused on the
discovery and development of novel treatments for viral diseases and cancer. The
Company's strategy aims to capitalize on its broad portfolio and original
expertise in virology. Ambrilia's product portfolio is comprised of oncology and
antiviral assets, including two new formulations of existing peptides for cancer
treatment, a therapeutic peptide for prostate cancer, a targeted delivery
technology for cancer, an HIV protease inhibitor program (exclusive worldwide
rights granted to Merck & Co., Inc.) as well as HIV integrase and entry
inhibitors, Hepatitis C virus inhibitors and anti-Influenza A compounds.
Ambrilia's head office, research and development and manufacturing facilities
are located in Montreal with a regional office in France.


For more information, please visit the Company's web site: www.ambrilia.com