Orthocell Receives Approval for Human Nerve Regeneration Study Using CelGro®
17 Outubro 2016 - 8:42PM
Business Wire
- Human ethics approval granted for a
study using Orthocell’s CelGro® collagen medical device for the
repair of nerve injuries
- Study designed to show CelGro® can be
used to guide and promote nerve regeneration in severed peripheral
nerves of the hand and upper limb
- Performed in collaboration with a
leading Australian orthopaedic nerve specialist and the St John of
God Hospital Group Subiaco, Perth
Regenerative medicine company Orthocell has been granted ethics
approval for a human study examining the effectiveness of its
CelGro® collagen medical device, to guide and promote nerve
regeneration in severed peripheral nerves of the hand and upper
limb.
The primary objective of this study is to demonstrate the
safety, tolerability and effectiveness of CelGro® when used as a
conduit in the surgical repair of peripheral nerve injuries. The
study will involve 20 patients who have suffered injury to one or
more peripheral nerves and will be undertaken at St John of God
Hospital beginning in the fourth quarter of calendar 2016.
Peripheral nerve injury is most commonly caused by accidents or
other trauma and in the US alone, over 20 million people are
affected each year, at a cost of approximately $150 billion in
annual health care dollars.
Principal investigator, orthopaedic surgeon Dr Alex O’Beirne
said: “This is an exciting development that has the potential to
improve patient outcomes by allowing for a suture-less repair to
the damaged nerve, to guide nerve regeneration and accelerate the
healing process.”
CelGro® is a biological medical device used as a scaffold for a
variety of orthopaedic and general reconstructive surgical
applications. Orthocell is also undertaking clinical studies using
CelGro® to augment repair of the rotator cuff tendon within the
shoulder, as an augment to guide and promote bone regeneration, as
well as an augment to cartilage repair within the hip joint.
Orthocell Managing Director Paul Anderson said, “This is an
exciting new phase in the development of CelGro® and its use as an
augment to improve nerve repair. It further validates CelGro as a
unique platform technology for soft tissue repair.”
Orthocell has submitted CelGro® for first regulatory approval in
Europe and expects to receive notice of approval of its CE Mark
application in 2016. Receipt of this approval will enable sales of
CelGro® to commence in Europe, and trigger applications for other
regulatory approvals in the United States, Australia and Japan in
2017.
About Orthocell Limited
Orthocell is a commercial-stage, regenerative medicine company
focused on regenerating mobility for patients and our ageing
population by developing products for a variety of tendon,
cartilage and soft tissue injuries. Orthocell’s portfolio of
products include TGA-approved stem cell therapies Autologous
Tenocyte Implantation (Ortho-ATI™) and Autologous Chondrocyte
Implantation (Ortho-ACI™), which aim to regenerate damaged tendon
and cartilage tissue. The Company’s other major product is CelGro™,
a collagen medical device which facilitates tissue repair and
healing in a variety of orthopaedic, reconstructive and surgical
applications and is being readied for first regulatory
approvals.
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Orthocell LimitedGeneral enquiriesPaul Anderson,
+61 8 9360 2888Managing
Directorpaulanderson@orthocell.com.auorInvestor and Media
enquiriesWE BuchanBen Walsh, +61 411 520
012bwalsh@buchanwe.com.au
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