IGC Pharma Expands Drug Portfolio to Metabolic Disorders with IGC-1A, A Potential New GLP-1 Agonist
20 Agosto 2024 - 9:00AM
Business Wire
- Artificial Intelligence Modelling Reveals New
Possibilities for Metabolic and Neurological Therapies -
IGC Pharma, Inc. (NYSE American: IGC) ("IGC Pharma" or the
"Company") today announced that the Company's proprietary molecule,
IGC-1A, has been identified as a potential GLP-1 agonist, as a
result of the Company's state-of-the-art Artificial Intelligence
("AI") modeling. This discovery highlights the versatility of IGC
Pharma's drug platforms and marks the Company's potential for
strategic expansion to metabolic disorders and weight loss.
Identifying IGC-1A as a potential GLP-1 agonist marks a
significant milestone for IGC Pharma, presenting a substantial
market opportunity and improving patient care for various
conditions. GLP-1 (glucagon-like peptide-1) is a powerful hormone
known for its dual role in managing blood sugar levels and
promoting weight loss. As GLP-1 agonists gain traction for their
effectiveness in treating type 2 diabetes and aiding weight
management by increasing satiety and reducing appetite, they are
also being explored for their neuroprotective benefits. This could
potentially revolutionize treatments for Alzheimer's disease by
addressing inflammation and oxidative stress, offering a
multifaceted approach to improving patient outcomes.
Ram Mukunda, CEO of IGC Pharma, commented, "Our AI-driven
approach has revealed a promising opportunity for IGC-1A and IGC-1C
to be potential GLP-1 agonists. This discovery strengthens our
Alzheimer's treatment portfolio and also positions us to
potentially enter the rapidly growing weight loss market. By
comparing IGC-1A and IGC-1C with established drugs such as Ozempic,
Tirzepatide, Retatrutide, and Metformin, among others, our AI model
indicates that they could become an effective option for metabolic
disorders. While we are in the early stages, our molecules allow us
to potentially build a portfolio that also focuses on metabolic
disorders and obesity with improved tolerability and efficacy
compared to current options.
"As we advance toward further validation through clinical
trials, we see substantial growth potential in developing
innovative treatments that address metabolic and neurodegenerative
conditions. Additionally, investigations into IGC-1A have revealed
its potential as a GLP-1 agonist, GIP agonist, and a CB1r inverse
agonist, opening new avenues for potentially impactful therapies in
weight management, neurological disorders, and metabolic
disorders."
In 2024, IGC Pharma anticipates progressing toxicology and
dosing studies in preparation for submitting an Investigational New
Drug Application for IGC-1A to the FDA although there can be no
assurance thereof. IGC Pharma's potential strategic expansion to
metabolic disorders underscores the Company's commitment to
leveraging advanced AI technology to drive innovation and develop
impactful solutions that create substantial value for
investors.
About IGC Pharma (dba IGC):
IGC Pharma is an AI-powered, clinical-stage biotechnology
company focused on developing innovative treatments for Alzheimer's
disease and transforming patient care with fast-acting, safe, and
effective solutions. Our portfolio includes the TGR family,
including TGR-63, which targets amyloid plaques, a hallmark of
Alzheimer's. The IGC-C and IGC-M platforms are advancing in
preclinical studies, focusing on metabolic disorders, tau proteins,
early plaque formation, and multiple disease hallmarks. Our lead
therapeutic candidate, IGC-AD1, is a cannabinoid-based treatment
currently in a Phase 2 trial for agitation in dementia associated
with Alzheimer's (clinicaltrials.gov, NCT05543681). Interim data
for IGC-AD1 demonstrated that it has the potential to transform
patient care by offering faster-acting and more effective relief
compared to traditional medications. Additionally, our AI models
are designed to predict potential biomarkers for the early
detection of Alzheimer's, optimize clinical trials, and predict
receptor affinity, among others. With 28 patent filings and a
commitment to innovation, IGC Pharma is dedicated to advancing
pharmaceutical treatments and improving the lives of those affected
by Alzheimer's and related conditions.
Forward-looking Statements
This press release contains forward-looking statements. These
forward-looking statements are based largely on IGC Pharma's
expectations and are subject to several risks and uncertainties,
certain of which are beyond IGC Pharma's control. Actual results
could differ materially from these forward-looking statements as a
result of, among other factors, the Company's failure or inability
to commercialize one or more of the Company's products or
technologies, including the products or formulations described in
this release, or failure to obtain regulatory approval for the
products or formulations, where required, or government regulations
affecting AI or the AI algorithms not working as intended or
producing accurate predictions; general economic conditions that
are less favorable than expected; the FDA's general position
regarding cannabis- and hemp-based products; and other factors,
many of which are discussed in IGC Pharma's U.S. Securities and
Exchange Commission ("SEC") filings. IGC incorporates by reference
its Annual Report on Form 10-K filed with the SEC on June 24, 2024,
and on Form 10-Q filed with the SEC on August 7, 2024, as if fully
incorporated and restated herein. Considering these risks and
uncertainties, there can be no assurance that the forward-looking
information contained in this release will occur.
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version on businesswire.com: https://www.businesswire.com/news/home/20240820622433/en/
IMS Investor Relations Rosalyn Christian / Walter Frank
igc@imsinvestorrelations.com (203) 972-9200
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