FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Herbert Timothy P.
2. Issuer Name and Ticker or Trading Symbol

Inspire Medical Systems, Inc. [ INSP ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
CEO and President
(Last)          (First)          (Middle)

C/O INSPIRE MEDICAL SYSTEMS, INC., 5500 WAYZATA BLVD., SUITE 1600
3. Date of Earliest Transaction (MM/DD/YYYY)

10/11/2022
(Street)

GOLDEN VALLEY, MN 55416
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 10/11/2022  M  27529 A$10.38 118679 D  
Common Stock 10/11/2022  M  41216 A$0.94 159895 D  
Common Stock 10/11/2022  M  42 A$42.15 159937 D  
Common Stock         22641 I By family trust (1)
Common Stock         22875 I By family trust (2)
Common Stock         113138 I By GRAT (3)
Common Stock         350 I By daughter 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy) $10.38 10/11/2022  M     27529   (4)4/9/2028 (5)Common Stock 27529 $0 85252 D  
Stock Option (Right to Buy) $0.94 10/11/2022  M     41216   (4)4/1/2027 Common Stock 41216 $0 0 (6)D  
Stock Option (Right to Buy) $42.15 10/11/2022  M     42   (7)12/18/2028 Common Stock 42 $0 84958 D  

Explanation of Responses:
(1) Shares held by the Timothy P. Herbert 2013 Family Irrevocable GST Trust U/A/D November 27, 2013.
(2) Shares held by the Margaret C. Herbert 2018 Family Irrevocable GST Trust.
(3) Securities held by the Timothy P. Herbert 2018 Grantor Retained Annuity Trust, under agreement dated December 12, 2018.
(4) The option is fully vested and exercisable.
(5) This option grant was previously reported as having an expiration date of April 8, 2028, which has been revised herein.
(6) Following the reported transactions, there are no remaining options held under this grant by the Reporting Person, either directly or indirectly.
(7) The option vested and became exercisable as to 25% of the underlying shares on the first anniversary of December 18, 2018 and the remaining 75% of the underlying shares have vested or will vest in 36 equal monthly installments thereafter, subject to the Reporting Person's continuous employment with the Issuer through the relevant vesting dates.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Herbert Timothy P.
C/O INSPIRE MEDICAL SYSTEMS, INC.
5500 WAYZATA BLVD., SUITE 1600
GOLDEN VALLEY, MN 55416
X
CEO and President

Signatures
/s/ Bryan Phillips, as Attorney-in-Fact for Timothy P. Herbert10/13/2022
**Signature of Reporting PersonDate


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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