Corning® Epic® System Enables Discovery of Novel Biological Processes
18 Junho 2009 - 9:30AM
Business Wire
Corning Incorporated (NYSE: GLW) today announced research
results using label-free Corning� Epic� technology to study new
areas of cell biology, which may yield important insights for basic
biological research and drug discovery applications.
According to research published recently in J Biol Chem
[284(2):1324, 2009], investigators from the University of Bonn have
uncovered a new way by which receptors regulate themselves and
limit the extent of their own cellular responses, thereby
preventing overstimulation. This is a significant development in
the current understanding of receptor biology and could help
discover better therapeutic drugs.
According to Professor Evi Kostenis, Ph.D, chair, Molecular,
Cellular and Pharmacobiology, Institute for Pharmaceutical Biology,
University of Bonn, Germany, and senior author of the J Biol Chem
study, �the novel technology is a breakthrough in both basic
research and drug development. To date, it has been impossible to
analyze activation of receptors and their various routes of
communication with the cell interior in living cells and real time.
The Epic biosensor has overcome this limitation: It captures
receptor-mediated rearrangements of intracellular components and
translates such rearrangements into specific optical signals. We
are pleased to take advantage of this technology to both discover
novel biological principles, but also to develop novel therapeutics
designed to interfere with very specific cellular functions.�
�This is a great example of how label-free technology is being
used to make new biological discoveries, and it underscores the
future potential of the technology,� added Ron Verkleeren, business
director, Corning Epic system.
Corning�s Epic system is the world�s first high-throughput,
label-free screening system. It uses patented optical biosensors
technology to measure a broad range of biochemical and cell-based
targets. The system was introduced in 2006 and has been deployed at
customer sites in North America, Europe, and Asia.
For additional information on the Epic system or any other
Corning Life Sciences products, please contact a customer service
representative at 1-800-492-1110, toll free in the United States,
(+1) 978-635-2200 internationally, or visit
www.corning.com/epic.
About Corning Incorporated
Corning Incorporated (www.corning.com) is the world leader in
specialty glass and ceramics. Drawing on more than 150 years of
materials science and process engineering knowledge, Corning
creates and makes keystone components that enable high-technology
systems for consumer electronics, mobile emissions control,
telecommunications and life sciences. Our products include glass
substrates for LCD televisions, computer monitors and laptops;
ceramic substrates and filters for mobile emission control systems;
optical fiber, cable, hardware & equipment for
telecommunications networks; optical biosensors for drug discovery;
and other advanced optics and specialty glass solutions for a
number of industries including semiconductor, aerospace, defense,
astronomy and metrology.
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