Gilead and Terray Therapeutics Announce Multi-Target Research Collaboration to Discover and Develop Novel Small Molecule Therapies
17 Dezembro 2024 - 9:00AM
Business Wire
-- Gilead and Terray Will Leverage Terray’s
tNova Drug Discovery Platform to Identify Small Molecule
Therapeutics Against Targets of Interest --
-- Gilead Has Exclusive Option to Develop and
Commercialize Products from the Collaboration --
Gilead Sciences, Inc. (Nasdaq: GILD) and Terray Therapeutics,
Inc. announced today that the companies have entered into a
strategic collaboration to discover and develop novel, small
molecule therapies across multiple targets.
This press release features multimedia. View
the full release here:
https://www.businesswire.com/news/home/20241217141411/en/
Terray’s tNova platform combines high-throughput chemical
experimentation and computational analysis with a generative
AI-driven drug discovery engine. The company’s iterative approach
applies AI-empowered methods to an extensive library of
quantitative, purpose-built, structure activity data to find the
right molecules to solve complex problems in drug discovery.
“Next-generation, AI-driven platforms using custom-generated
large, relevant data sets will serve as important tools in our
efforts to shape the future of drug discovery in our ongoing
pursuit of innovative treatments across our therapeutic areas of
focus,” said Flavius Martin, M.D., Executive Vice President,
Research, Gilead Sciences. “We are excited to collaborate with
Terray and explore how their integrated discovery platform will
complement our own internal research capabilities and
expertise.”
“We’re proud to strategically partner with Gilead,” said Jacob
Berlin, Ph.D., Chief Executive Officer, Terray Therapeutics. “We’re
very excited to put tNova’s unique blend of experimentation and
computation to work alongside the deep expertise of our
collaborators at Gilead to find transformational small molecule
therapeutics that bring relief to patients in need.”
Terms of the Agreement
Under the terms of the agreement, Terray will utilize the Terray
tNova platform to discover and develop small molecule compounds
against a set of targets selected by Gilead. If Gilead exercises
its option to exclusively license the compounds directed to a
target, Gilead will be responsible for further development and
commercialization activities for products resulting from the
collaboration. Terray will receive an upfront payment and is
eligible to receive milestone payments associated with the
achievement of preclinical, clinical, and sales milestones as well
as tiered royalties on net sales of products commercialized by
Gilead in connection with the collaboration.
Gilead does not exclude acquired IPR&D expenses from its
non-GAAP financial measures. This transaction with Terray is
expected to reduce Gilead’s GAAP and non-GAAP 2024 EPS by
approximately $0.01.
About Terray
Therapeutics
Terray is an AI-powered biotechnology company with the
technology, data, and mindset to radically change the way we
discover and develop small molecule therapeutics. The company
explores molecules and targets with a sophisticated integration of
ultra-high throughput experimentation, generative AI, biology,
medicinal chemistry, automation, and nanotechnology. Terray's
platform uniquely blends experimentation and computation to deliver
on the promise of generative AI for small molecule
discovery—finding solutions to the toughest therapeutic challenges.
To learn more about Terray, please visit terraytx.com and follow
Terray Therapeutics on LinkedIn.
About Gilead Sciences
Gilead Sciences, Inc. is a biopharmaceutical company that has
pursued and achieved breakthroughs in medicine for more than three
decades, with the goal of creating a healthier world for all
people. The company is committed to advancing innovative medicines
to prevent and treat life-threatening diseases, including HIV,
viral hepatitis, COVID-19, and cancer. Gilead operates in more than
35 countries worldwide, with headquarters in Foster City,
Calif.
Gilead Forward-Looking
Statement
This press release includes forward-looking statements within
the meaning of the Private Securities Litigation Reform Act of 1995
that are subject to risks, uncertainties and other factors,
including Gilead’s ability to realize the anticipated benefits from
the collaboration; difficulties or unanticipated expenses in
connection with the collaboration and the potential effects on
Gilead’s earnings; the ability of the parties to initiate, progress
or complete clinical trials within currently anticipated timelines
or at all, and the possibility of unfavorable results from ongoing
or additional trials, including those involving programs developed
pursuant to the collaborations; the ability of the parties to file
applications for regulatory approval or receive regulatory
approvals in a timely manner or at all for the investigational
programs developed pursuant to the collaborations, and the risk
that any such approvals may be subject to significant limitations
on use; the possibility that the parties may make a strategic
decision to discontinue development of any of the investigational
programs developed pursuant to the collaborations, and therefore
these programs may never be successfully commercialized; and any
assumptions underlying any of the foregoing. These and other risks,
uncertainties and other factors are described in detail in Gilead’s
Quarterly Report on Form 10-Q for the quarter ended September 30,
2024, as filed with the U.S. Securities and Exchange Commission.
These risks, uncertainties and other factors could cause actual
results to differ materially from those referred to in the
forward-looking statements. All statements other than statements of
historical fact are statements that could be deemed forward-looking
statements. The reader is cautioned that any such forward-looking
statements are not guarantees of future performance and involve
risks and uncertainties and is cautioned not to place undue
reliance on these forward-looking statements. All forward-looking
statements are based on information currently available to Gilead,
and Gilead assumes no obligation and disclaims any intent to update
any such forward-looking statements.
Gilead and the Gilead logo are trademarks of
Gilead Sciences, Inc., or its related companies.
For more information about Gilead, please visit
the company’s website at www.gilead.com, follow Gilead on X/Twitter
(@Gilead Sciences) and LinkedIn (@Gilead-Sciences).
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Gilead Info
Jessica Smith, Media public_affairs@gilead.com
Jacquie Ross, Investors investor_relations@gilead.com
Terray Info
press@terraytx.com
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